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165 Cards in this Set
- Front
- Back
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Carcinoma Epidermóide queratinizante |
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Birefringent uric acid crystals in urine |
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Candida spp. in voided urine |
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cels uroteliais reativas |
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celulas basais do urotélio |
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celulas normais do urotelio |
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citologia normal com negatividade para neoplasia |
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Citologia normal |
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CMV-infected cells with large eosinophilic intranuclear inclusion surrounded by clear halo |
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Columnar cells in voided urine |
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Corpora amylacea-voided urine. Corpora amylacea are laminated structures, staining blue-green here; they occur more with advancing age and are derived from degenerate cells |
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Degenerated atypical urothelial cells showing slight anisonucleosis and bland chromatin in bladder catheterized specimen |
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Endometrial cells—voided urine |
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few cells exhibit classic features of high-grade urothelial carcinoma- HGUC |
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Group of malignant cells from high-grade urothelial carcinoma of bladder. The nuclei display an irregular chromatin pattern and contain nucleoli. The cytoplasm is focally eosinophilic |
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HGUC |
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High-grade urothelial carcinoma (HGUC) displays coarse chromatin and nuclear membrane irregularity |
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High-grade urothelial carcinoma (HGUC) present as a cohesive group of malignant cells |
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High-grade urothelial carcinoma (UC). A cluster of malignant urothelial cells, some with prominent nucleoli |
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High-grade urothelial carcinoma (UC). Numerous isolated malignant cells have enlarged nuclei with coarsely textured chromatin and an increased nuclear-to-cytoplasmic ratio |
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High-grade urothelial carcinoma Cluster of malignant cells exhibiting many diagnostic features including pleomorphism |
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High-grade urothelial carcinoma Cluster of malignant cells with hyperchromatic nuclei. |
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High-grade urothelial carcinoma coarse chromatin pattern |
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High-grade urothelial carcinoma marked nuclear hyperchromasia |
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High-grade urothelial carcinoma of bladder. Large pleomorphic tumor cells with irregular nuclei and a coarsely granular chromatin pattern |
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High-grade urothelial carcinoma of bladder. The nuclei are very large and contain prominent nucleoli |
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High-grade urothelial carcinoma with squamous differentiation |
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High-grade urothelial carcinoma. Considerable nuclear pleomorphism and hyperchromasia are seen. The nucleocytoplasmic ratio is high |
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High-grade urothelial carcinoma—voided urine. |
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Histiocyte-containing intracytoplasmic laminated inclusions consistent with malakoplakia |
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Large superficial umbrella and smaller pyramidal or basal cells. Some of the superficial cells are multinucleated and contain nucleoli |
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low-grade urothelial lesion (catheterized specimen). Benign cell clusters have a smooth outline (“collared” groups). |
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low-grade urothelial lesion Low-grade lesions tend to exfoliate as clusters with irregular edges |
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Multinucleated superficial urothelial cell. |
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Normal urothelial cells. A papillary cluster of urothelial cells with rounded edge is often seen in patients with proven ureteric calculi |
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Normal urothelial cells. The large cells are from the superficial and the small cells from the basal layers |
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Normal voided urine. Most benign voided urine samples show a mixture of urothelial cells and squamous cells In voided urine, most of the urothelial cells are of intermediate type, with an oval or pyramidal shape |
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Polyoma virus infected cell. The cell in the centre of the field has an eccentrically placed nuclei, the chromatin of the cell appears glassy |
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Polyoma virus infected cells |
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Polyoma virus |
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Polyomavirus infection. Some enlarged, round nuclei are virtually replaced by a glassy, homogeneous inclusion. |
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Polyomavirus-infected cells with large intranuclear homogeneous inclusions |
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Reactive urothelial cells (catheterized urine). Coarsely vacuolated cytoplasm is characteristic of benign, reactive changes and uncommon in malignancy. |
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Reactive urothelial cells |
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reativas uroteliais |
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Renal tubular epithelial cells. The cells are of a size similar to that of immature urothelial cells and have uniform, round nuclei |
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Schistosoma haematobium. Ova of the Schistosoma haematobium. Voided urine |
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Single abnormal urothelial cells with enlarged hyperchromatic nuclei in urothelial carcinoma in situ of bladder |
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Aspeto das umbrella cells em urotélio |
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Spermatozoa-voided urine |
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Superficial umbrella cells, with a multinucleated cell in an umbrella configuration |
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Superficial urothelial (arrow) and superficial squamous cell. Superficial urothelial cells (umbrella cells) are often bi- or multinucleated and have abundant cytoplasm |
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Triple phosphate crystals.typical coffin lid appearance |
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Umbrella cell com duas celulas pavimentosas |
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Umbrella cells. These are the largest urothelial cells and cover the surface of the urothelium. Normal columnar urothelial cells are also present |
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Uric acid crystals—voided urine. Uric acid crystals showing large variation in appearance |
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uroteliais reativas |
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Urothelial carcinoma (UC) variants. Some of the malignant cells show squamous differentiation, manifested by cytoplasmic orangeophilia |
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Urothelial carcinoma (UC) variants. Some UCs have foci of adenocarcinoma |
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Urothelial cells in a papillary group from a patient with calculus disease. Note smooth borders that suggest a benign process |
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Urothelial cells with prominently vacuolated cytoplasm |
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Voided urine in a case of high-grade urothelial carcinoma of bladder. The loose cluster of cells shows large, moderately irregular nuclei with a high nucleocytoplasmic ratio |
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Agrupamento de baixo grau |
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Alto grau com elevada hipercromasia formação papilas pleomorfismo e escasso citoplasma |
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ALTO GRAU |
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Alto grau |
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Baixo grau |
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Baixo grau |
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Baixo grau |
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Basais reativas com inflamação |
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Basais reativas |
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Cândida hifas e esporos |
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Cel umbrella |
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Citologia suspeita |
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Citologia suspeita |
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Esporos e hifas |
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Baixo grau |
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Baixo grau |
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Baixo grau |
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Suspeito |
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Baixo grau |
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Suspeito |
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Baixo grau |
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Cocos e esporos de candida |
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Baixo grau |
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Baixo grau |
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Baixo grau |
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Suspeito |
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Lesão baixo grau |
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Pavimentosa à esquerda e uroteliais á direita |
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Proteína com PMN |
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Suspeito |
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Suspeita célula isolada |
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Citologia suspeita |
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Citologia suspeita |
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Umbrella cell |
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Umbrella com PMN e uroteliais degeneradas |
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Uroteliais a de baixo um pouco reativa |
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Uroteliais com aspeto colunar |
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Uroteliais intermédias |
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Uroteliais normais |
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Uroteliais reativas |
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Urotelial umbrella |
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Urotelial reativa núcleos aumentados |
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Adenocarcinoma
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Alto grau em urina
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Alto grau urina
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Bacterias
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Candida
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Carcinoma epidermoide queratinizante
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Células uroteliais de aspecto colunar
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Células uroteliais num fundo inflamatório
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Cluster urotelial benigno- contornos nucleares normais núcleo central cromatina granular aumento nuclear e celular uniforme
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Grupo de células uroteliais com aumento nuclear e cromatina grumosa – sugestivo de Lesão de Baixo Grau
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Lesao de alto grau em urina
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Lesão de alto grau urina
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Lesão de alto grau
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Lesão de alto grauu
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Lesao de baixo grau - Células isoladas e em pequenos grupos
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Umbrella cell
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Urina normal- Células pavimentosas, uroteliais benignas e PMN
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Urina normal- celulas uroteliais reativas
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Urina normal- uroteliais em agrupamento
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Urina por cateterização cristais
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Uroteliais
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pavimentosas e uroteliais
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Umbrela cell dta e e urotelial esq devido ao aspeto citoplasma e ligeiro reforço que o citoplasma faz á periferia
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Umbrella cell- multiplos nucleos com nucleolos proeminentes
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candida com esporos e hifas e inflamção com PMN
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pavimentosas quetainizadas com cocos e esporos candida
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Urina- agrupamento uroteliais basais, com uroteliais intermedias
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cocos á dta com hifas á esq e PMN (inflamação)
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Urina- PMN (inflamção) com urrotelial e pavimentosa
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Urina- uroteliais basais
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Urina- uroteliais devido ao formato cuboidal e citoplasma espumoso
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uroteliais dta e urotelial esq devido ao citoplasma e forma cuboidal
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Urina - lesão de baixo grau
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Lesao de baixo grau urina
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Urina - metaplasia uroteliais
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Urina- carci queratinizante
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Urina lesao baixo grau
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Lesão de alto grau
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alto grau Cells of high grade urothelial carcinoma are pleomorphic and nuclei may contain a prominent, irregular nucleolus
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alto grau Cells of high grade urothelial carcinoma have high N-C ratios
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alto grau Cells of high grade urothelial carcinoma may be clustered
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alto grau Chromatin in nuclei of high grade carcinoma is coarse and hyperchromatic
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alto grau Chromatin in nuclei of high grade carcinoma is coarse, hyperchromatic and often irregularly dispersed
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alto grau Nuclei may be pointed in high grade urothelial carcinoma
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alto grau Nuclei of high grade urothelial carcinoma are often eccentric with convoluted, thickened membranes
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alto grau Nuclei of high grade urothelial carcinoma may have multiple irregular nucleoli
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alto grau urina
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alto grau Urothelial tumors may be papillary or non-papillary
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alto grau
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baixo grau cells in the clusters of low grade urothelial carcinoma have high N-C ratios
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baixo grau Cells of low grade urothelial carcinoma may be in small groups with some single cells
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baixo grau Chromatin in low grade urothelial carcinoma is usually granular and evenly distributed
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baixo grau clusters in low grade urothelial carcinoma may or may not be papillary
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baixo grau Compare the normal urothelial on the right to the crowded cluster on the left.
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baixo grau loose cluster of cells from low grade urothelial carcinoma can be compared to reactive urothelial cells
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baixo grau Nuclei in low grade urothelial carcinoma sometimes bulge out of the cytoplasm
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baixo grau Nuclei of low grade urothelial carcinoma are irregular and may appear to have notches or grooves
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baixo grau Nucleoli are usually indistinct or absent in low grade urothelial carcinoma
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benigno clusters of cells
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Lesão de alto grau. High grade urothelial carcinomas often are abundantly cellular
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uroteliais reativas nuclear enlargement, hyperchromasia, prominent nucleoli and occasiona
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