White Sponge Nevus Case Study

1577 Words 7 Pages
White sponge nevus (WSN) is a rare autosomal dominant disorder that results in soft, white, and spongy plaques in the oral cavity. The buccal mucosa is the most commonly affected site, followed by lips, alveolar ridges and floor of the mouth. The histopathologic features of WSN include epithelial thickening, hyperkeratosis and vacuolization of the keratinocytes in the suprabasal layers. Because of lack of clinical complaint, no treatment has been proposed, thus clinical follow-up is used as the chosen means of management. Here is a case report of white sponge nevus in a 25 year old male patient affecting the right buccal mucosa.
Key words: Dyskeratosis, white lesion, white sponge nevus
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It was smaller in size but has gradually attained its present size during the span of 5-6 years. There is no relevant past dental history or medical history. In the family history, patient’s brother also had similar type of patch in relation to his left buccal mucosa since 25 years (Figure 2). On general physical examination all the vital signs were in normal range. No abnormality was detected on systemic evaluation and extra-oral examination. On intra-oral examination a white plaque with well defined margins, which is translucent measuring approximately 2.5 x 2.0 cm was present in relation to right buccal mucosa extending anteroposteriorly 0.5 cm away from retro commissural area to middle of buccal mucosa and supero-inferiorly above and below occlusal line. On palpation it was smooth and shiny, soft, non-tender and non–scrappable. Based on history and clinical examination a provisional diagnosis of White sponge nevus was given with a differential diagnosis homogenous leukoplakia, pseudomembranous candidiasis and dyskeratosis congenita. On haematological investigations all the values were within normal limits and a punch biopsy was performed as an investigative procedure. The histopathological report revealed hyperplastic epithelium with hyperparakeratinization and acanthosis, broad, and elongated rete …show more content…
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