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75 Cards in this Set

  • Front
  • Back
Central nervous system (CNS) makes up:
brain and spinal cord
Peripheral nervous system (PNS) makes up
all nerves that connect CNS to rest of body
Afferent division in PNS:
sensory
-peripheral nerves that carry sensory info from receptor to CNS (towar CNS)
Efferent division in PNS:
motor
-to muscles and glands
-exiting/leaving CNS and out to the body
Efferent division has two divisons:
1) somatic division
2) autonomic division
Somatic division:
voluntary control over skeletal muscles
autonomic division:
involuntary control
1)sympathetic "fight or flight"
-response to unusual stimulus
-remember "E" division: exercise, excitement, emergency, and embarrassment

2)parasympathetic: housekeeping activities (conserve energy)
-remember as "D" division: digestion, defecation, and diuresis
-maintain basic body functions
General functions of Nervous system:
1) sensory
2) motor
3) regulate physiologic processes
4) intellect- memory, problem solving
Sensory Function:
gathering information
-involves sensory receptors at end of peripheral nerves
-these pick up info inside and outside body
-change=stimuli
Integrative function:
-info picked up by receptors is converted into nerve impulses
-travel over PNS to CNS-afferent
-when 2 systems are integrated, results in perceptions

-we act either consciously or subconsciously by the motor function
Motor Function:
-impulses travel from CNS (efferent) over peripheral nerves to "effectors"
-effectors are responsive part and lie outside of the nervous system

-detect change -> make decision -> cause muscles and glands to respond
Nervous Tissue:
-neuron=single nerve fiber
-made up of neurons (nerve cells)=structural and functional units of nervous system
-also find neuroglial cells (surround and support) = accessory cells;act like CT
-brain and spinal cord
General features of Neuron Structure:
Excitable - transmit an action potential

Amitotic - do not divide
5 parts of the cell body (soma) of the Neural Structure
1) perikaryon
2) neurofibrils
3) nissal bodies
4) mononucleate
5) axon hillock
The Perikaryon of the cell body:
cytoplasm - found other organelles
The neurofibrils of the cell body:
network of fine threads; provides support
The nissal bodies of the cell body:
membranous sacs similar to rough ER - find ribosomes attached
The mononucleate of the cell body:
one nucleus and nucleolus
The axon hillock of the cell body:
connects axon to soma - where cell body tapers and joins axon
Two components of nerve fibers are:
1) Dendrites
2) axon
Dendrites function in the nerve fibers is:
usually many/nerve cell
-short and highly branched
-act as main receptive sites
-where processes from other neurons communicate
-some have dendritic spines - act as contact points
Axon function/structure in the nerve fiber is:
only 1 per cell
-slender cylindrival process with uniform diameter
-conducts impulses away from soma
-can give off branches called collaterals
-each collateral has extensions that end with a pre-synaptic (communicates with dendritic spines from the next)terminal that contacts receptive surfaces of another cell
Axonal transport in the axon has two types
1)anterograde
2)retrograde
The axonal transport in the axon is:
axoplasmis flow = intracellular movement
Anterograde is:
the movement away from soma; neurotransmitters, organelles, nutrients
Retrograde is:
movement toward soma; degrades materials to be recycled and extracellular substances
Axoplasm in the axon is:
the cytoplasm
-few organelles
-cytoskeletal proteins
-form cytoskeleton
-maintain shape
-generate axoplasmic flow
axolemma in the axon is:
the plasma membrane
the telodendria in the axon is:
fine branches at end of axon and collateral branches
The synaptic (axon) terminal in the axon is:
-find synaptic knob with synaptic vesicles (neurotransmitter)
Unipolar structural classification of Neurons is:
-several small dendrites converge onto one large dendrite
-dendrites and axon are continuous
-usually myelinated

ex: sensory neurons of PNS
bipolar structural classification of neurons is:
-several small dendrites converge onto one dendrite
-dendrite and axon separated by soma
-unmyelinated

ex: special sensory organs of CNS
Multipolar structural classification of neurons is:
-many dendrites extend from soma
-axon typically long
-usually myelinated

ex:lower motor neurons
anaxonis structural classification of neurons if:
-very small
-axons can not be visually distinguished from dendrites

ex:special sense organs of CNS
(especially in eye)
Sensory functional classification of Neurons is:
(afferent)
-carry impulses from peripheral body parts into brain or spinal cord
-have receptor ends on dendrites or dendrites are associated with receptor cells in sensory organs
-most are unipolar;few bipolar
-usually myelinated
Motor functional classification of Neurons is:
a) somatic - skeletal muscle
-innervate skeletal muscles
-multipolar and myelinated

b) visceral (autonomic)
-innervates all other effectors
-usually multipolar and myelinated
-everything else except skeletal muscle
interneurons functional classification of neurons is:
(associated; intercalated; internuncial)

-in CNS;brain and spinal cord
-most abundant
-act to link 2 neurons
-b/w 2 neurons
Anatomical organizations of neurons in NS in the PNS:
a) soma are located in ganglia
1)sensory neurons
2)autonomic neurons

b)axons located in nerves
Anatomical organizations of neurons in NS in the CNS:
a)soma located in nuclei

b) axons located in tracts
-2 or more tracts =column
The synapse is:
the site of communication between:
- neuron and an effector
- 2 neurons; most common; named based on structure
axodendrictic -
=0-----<=0-----<

dendrites forward
axosomatic -
=0----<0----<

dendrites on the side
axoaxonic -
0
-
-
-
-
>
0----------<
2 types of synapses:
1) chemical
2) electrical
Chemical synapses:
- most common
- AP in presynaptic cell -> neurotransmitter is released -> AP in post synaptic cell
Electrical synapse:
rare (only in CNS)
-AP's transmitted across gap junctions
four types of neuroglial cells in CNS:
1)astrocytes
2)oligodendrocytes
3)microglia
4)ependymal
Astrocytes (neuroglial cell) in CNS:
-star-shaped cells between neurons and blood vessels

1)structural support (holds parts together)

2)metabolism (glucose;brain food)

3)regulate concentration of ions in interstitial fluid (potassium)

4)respond to injury (in brain)
- responsible for scar tissue)

5)nutrition (oxygen, glucose)

6) guide developing neurons to targets (guide new neurons to targets)

7)help form blood-brain barrier (decide what gets and what stays)
Oligodendrocytes (neuroglial cells) in CNS:
-look like astrocytes but smaller
-arranged in rows along nerve fibers

1)form myelin in brain and spinal cord

2)sequester debris after injury
microglia (neuroglial cells) in CNS:
-smallest and least common

1)supports neurons

2)phagocytize basteria and debris

3)see increase numbers when brain and spinal cord is inflamed
ependymal (neuroglial cell) in CNS:
-columnar.cuboidal epithelium
-see microvilli and cilia on luminal surface
-joined by gap junctions

found:
1)covers ventricles (space in brain) of brain
2)inner lining of central canal in spinal cord

function:
1)help produce CSF (cerebral spinal fluid)
2)form porous layer for diffusion
3)circulate and monitor CSF composition
Two types of Neuroglial cell in PNS:
1)satellite cells

2)schwann cells
Satelite cell (neuroglial cell) in PNS:
-associated with soma
-assist with exchange of nutrients and wastes
-help isolate neuron from stimuli other than those provided at synapse
Schwann cell (neuroglial cell) in PNS:
=neurolemmocytes
-produce myeline in PNS

function:
1)support neurons
2)prevent contact between axons
3)myelinate large axons

-enclose the axons
-one schwann cell myelinates one axon
Unmyelinated axons:
appear gray

a)PNS axons
-many axons can associate with a single schwann cell

b)CNS axons
-no associated glia (schwann cell)
four functions in a Myelinated Axon:
1)myelin
2)neurilemma
3)nodes of ranvier
4)myelination process
5)in CNS & PSN
Myelin in a Myelinated Axon:
=plasma membrane of glial cell that wraps around axon

-membrane made of lipoprotain
neurilemma in a Myelinated Axon:
=part of schwann cell that contains sytoplasm

-surrounds myelin sheath
-outside where you find cytoplasm,etc...
node of ranvier in a Myelinated Axon:
=gaps in myelin sheath between adjacent schwann celss

-set up an action potential
myelination process in a Myelinated Axon:
-begins around week 14 (fetus)
-completed by 2-3 years
steps at chemical synapse:
a)AP reaches synaptic knob of presynaptic neuron

b)get released of neurotansmitter

c)neurotransmitter crosses cleft and binds to receptors in postsynaptic membrane

d)results in change in permeability of postsynaptic neuron
-degree of excitation may initiate an AP on postsynaptic membrane
-effects of neurotransmitter fades quickly
Neuronal pools:
-organized groups of neurons in CNS
-receives impulses from afferent nerve fibers (input)
-impulses processed based on characteristics of pool
-resulting impulses carried away on efferent fibers (output)
-an afferent fiber may divide many times as it enter a pool
Facilitation:
-due to different incoming impulses, one neuron may receive both excitatory and inhibitory stimuli
-outgoing only sent if net effect is excitatory and enough to reach threshold
-it net effect is excitatory but sub-threshold;no impulse sent but nerve is more excitable = facilitated
Convergence:
-a single nerve in a pool may receive impulses from 2 or more imcoming fibers
-when they lead to same nerve, they are said to converge
-allows a nerve to summate impulses
-allows nervous system to bring information together from a variety of sources
Divergence:
-when an impulses leaves a pool, it may spread into several output fibers
-allows an impulse to be amplified
Serial Processing:
-one neuron to another in series
Parallel Processing:
processing information from several neurons at once
Reverberation:
positive feedback continues activity of circuit
Ganglia:
collection of neuron cell bodies in PNS
nuclei:
collection of nerve cell bodies in CNS
center:
collection of neuron cell bodies working together in CNS
tracts:
bundles of axons in CNS
nerves:
bundles of axons in PNS
white matter:
myelinated axons
gray matter:
non-myelinated material