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75 Cards in this Set
- Front
- Back
Central nervous system (CNS) makes up:
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brain and spinal cord
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Peripheral nervous system (PNS) makes up
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all nerves that connect CNS to rest of body
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Afferent division in PNS:
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sensory
-peripheral nerves that carry sensory info from receptor to CNS (towar CNS) |
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Efferent division in PNS:
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motor
-to muscles and glands -exiting/leaving CNS and out to the body |
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Efferent division has two divisons:
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1) somatic division
2) autonomic division |
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Somatic division:
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voluntary control over skeletal muscles
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autonomic division:
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involuntary control
1)sympathetic "fight or flight" -response to unusual stimulus -remember "E" division: exercise, excitement, emergency, and embarrassment 2)parasympathetic: housekeeping activities (conserve energy) -remember as "D" division: digestion, defecation, and diuresis -maintain basic body functions |
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General functions of Nervous system:
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1) sensory
2) motor 3) regulate physiologic processes 4) intellect- memory, problem solving |
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Sensory Function:
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gathering information
-involves sensory receptors at end of peripheral nerves -these pick up info inside and outside body -change=stimuli |
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Integrative function:
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-info picked up by receptors is converted into nerve impulses
-travel over PNS to CNS-afferent -when 2 systems are integrated, results in perceptions -we act either consciously or subconsciously by the motor function |
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Motor Function:
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-impulses travel from CNS (efferent) over peripheral nerves to "effectors"
-effectors are responsive part and lie outside of the nervous system -detect change -> make decision -> cause muscles and glands to respond |
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Nervous Tissue:
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-neuron=single nerve fiber
-made up of neurons (nerve cells)=structural and functional units of nervous system -also find neuroglial cells (surround and support) = accessory cells;act like CT -brain and spinal cord |
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General features of Neuron Structure:
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Excitable - transmit an action potential
Amitotic - do not divide |
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5 parts of the cell body (soma) of the Neural Structure
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1) perikaryon
2) neurofibrils 3) nissal bodies 4) mononucleate 5) axon hillock |
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The Perikaryon of the cell body:
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cytoplasm - found other organelles
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The neurofibrils of the cell body:
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network of fine threads; provides support
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The nissal bodies of the cell body:
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membranous sacs similar to rough ER - find ribosomes attached
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The mononucleate of the cell body:
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one nucleus and nucleolus
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The axon hillock of the cell body:
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connects axon to soma - where cell body tapers and joins axon
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Two components of nerve fibers are:
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1) Dendrites
2) axon |
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Dendrites function in the nerve fibers is:
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usually many/nerve cell
-short and highly branched -act as main receptive sites -where processes from other neurons communicate -some have dendritic spines - act as contact points |
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Axon function/structure in the nerve fiber is:
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only 1 per cell
-slender cylindrival process with uniform diameter -conducts impulses away from soma -can give off branches called collaterals -each collateral has extensions that end with a pre-synaptic (communicates with dendritic spines from the next)terminal that contacts receptive surfaces of another cell |
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Axonal transport in the axon has two types
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1)anterograde
2)retrograde |
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The axonal transport in the axon is:
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axoplasmis flow = intracellular movement
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Anterograde is:
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the movement away from soma; neurotransmitters, organelles, nutrients
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Retrograde is:
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movement toward soma; degrades materials to be recycled and extracellular substances
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Axoplasm in the axon is:
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the cytoplasm
-few organelles -cytoskeletal proteins -form cytoskeleton -maintain shape -generate axoplasmic flow |
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axolemma in the axon is:
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the plasma membrane
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the telodendria in the axon is:
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fine branches at end of axon and collateral branches
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The synaptic (axon) terminal in the axon is:
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-find synaptic knob with synaptic vesicles (neurotransmitter)
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Unipolar structural classification of Neurons is:
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-several small dendrites converge onto one large dendrite
-dendrites and axon are continuous -usually myelinated ex: sensory neurons of PNS |
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bipolar structural classification of neurons is:
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-several small dendrites converge onto one dendrite
-dendrite and axon separated by soma -unmyelinated ex: special sensory organs of CNS |
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Multipolar structural classification of neurons is:
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-many dendrites extend from soma
-axon typically long -usually myelinated ex:lower motor neurons |
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anaxonis structural classification of neurons if:
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-very small
-axons can not be visually distinguished from dendrites ex:special sense organs of CNS (especially in eye) |
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Sensory functional classification of Neurons is:
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(afferent)
-carry impulses from peripheral body parts into brain or spinal cord -have receptor ends on dendrites or dendrites are associated with receptor cells in sensory organs -most are unipolar;few bipolar -usually myelinated |
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Motor functional classification of Neurons is:
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a) somatic - skeletal muscle
-innervate skeletal muscles -multipolar and myelinated b) visceral (autonomic) -innervates all other effectors -usually multipolar and myelinated -everything else except skeletal muscle |
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interneurons functional classification of neurons is:
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(associated; intercalated; internuncial)
-in CNS;brain and spinal cord -most abundant -act to link 2 neurons -b/w 2 neurons |
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Anatomical organizations of neurons in NS in the PNS:
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a) soma are located in ganglia
1)sensory neurons 2)autonomic neurons b)axons located in nerves |
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Anatomical organizations of neurons in NS in the CNS:
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a)soma located in nuclei
b) axons located in tracts -2 or more tracts =column |
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The synapse is:
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the site of communication between:
- neuron and an effector - 2 neurons; most common; named based on structure |
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axodendrictic -
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=0-----<=0-----<
dendrites forward |
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axosomatic -
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=0----<0----<
dendrites on the side |
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axoaxonic -
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0
- - - - > 0----------< |
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2 types of synapses:
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1) chemical
2) electrical |
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Chemical synapses:
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- most common
- AP in presynaptic cell -> neurotransmitter is released -> AP in post synaptic cell |
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Electrical synapse:
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rare (only in CNS)
-AP's transmitted across gap junctions |
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four types of neuroglial cells in CNS:
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1)astrocytes
2)oligodendrocytes 3)microglia 4)ependymal |
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Astrocytes (neuroglial cell) in CNS:
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-star-shaped cells between neurons and blood vessels
1)structural support (holds parts together) 2)metabolism (glucose;brain food) 3)regulate concentration of ions in interstitial fluid (potassium) 4)respond to injury (in brain) - responsible for scar tissue) 5)nutrition (oxygen, glucose) 6) guide developing neurons to targets (guide new neurons to targets) 7)help form blood-brain barrier (decide what gets and what stays) |
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Oligodendrocytes (neuroglial cells) in CNS:
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-look like astrocytes but smaller
-arranged in rows along nerve fibers 1)form myelin in brain and spinal cord 2)sequester debris after injury |
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microglia (neuroglial cells) in CNS:
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-smallest and least common
1)supports neurons 2)phagocytize basteria and debris 3)see increase numbers when brain and spinal cord is inflamed |
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ependymal (neuroglial cell) in CNS:
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-columnar.cuboidal epithelium
-see microvilli and cilia on luminal surface -joined by gap junctions found: 1)covers ventricles (space in brain) of brain 2)inner lining of central canal in spinal cord function: 1)help produce CSF (cerebral spinal fluid) 2)form porous layer for diffusion 3)circulate and monitor CSF composition |
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Two types of Neuroglial cell in PNS:
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1)satellite cells
2)schwann cells |
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Satelite cell (neuroglial cell) in PNS:
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-associated with soma
-assist with exchange of nutrients and wastes -help isolate neuron from stimuli other than those provided at synapse |
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Schwann cell (neuroglial cell) in PNS:
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=neurolemmocytes
-produce myeline in PNS function: 1)support neurons 2)prevent contact between axons 3)myelinate large axons -enclose the axons -one schwann cell myelinates one axon |
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Unmyelinated axons:
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appear gray
a)PNS axons -many axons can associate with a single schwann cell b)CNS axons -no associated glia (schwann cell) |
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four functions in a Myelinated Axon:
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1)myelin
2)neurilemma 3)nodes of ranvier 4)myelination process 5)in CNS & PSN |
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Myelin in a Myelinated Axon:
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=plasma membrane of glial cell that wraps around axon
-membrane made of lipoprotain |
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neurilemma in a Myelinated Axon:
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=part of schwann cell that contains sytoplasm
-surrounds myelin sheath -outside where you find cytoplasm,etc... |
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node of ranvier in a Myelinated Axon:
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=gaps in myelin sheath between adjacent schwann celss
-set up an action potential |
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myelination process in a Myelinated Axon:
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-begins around week 14 (fetus)
-completed by 2-3 years |
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steps at chemical synapse:
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a)AP reaches synaptic knob of presynaptic neuron
b)get released of neurotansmitter c)neurotransmitter crosses cleft and binds to receptors in postsynaptic membrane d)results in change in permeability of postsynaptic neuron -degree of excitation may initiate an AP on postsynaptic membrane -effects of neurotransmitter fades quickly |
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Neuronal pools:
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-organized groups of neurons in CNS
-receives impulses from afferent nerve fibers (input) -impulses processed based on characteristics of pool -resulting impulses carried away on efferent fibers (output) -an afferent fiber may divide many times as it enter a pool |
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Facilitation:
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-due to different incoming impulses, one neuron may receive both excitatory and inhibitory stimuli
-outgoing only sent if net effect is excitatory and enough to reach threshold -it net effect is excitatory but sub-threshold;no impulse sent but nerve is more excitable = facilitated |
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Convergence:
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-a single nerve in a pool may receive impulses from 2 or more imcoming fibers
-when they lead to same nerve, they are said to converge -allows a nerve to summate impulses -allows nervous system to bring information together from a variety of sources |
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Divergence:
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-when an impulses leaves a pool, it may spread into several output fibers
-allows an impulse to be amplified |
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Serial Processing:
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-one neuron to another in series
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Parallel Processing:
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processing information from several neurons at once
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Reverberation:
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positive feedback continues activity of circuit
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Ganglia:
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collection of neuron cell bodies in PNS
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nuclei:
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collection of nerve cell bodies in CNS
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center:
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collection of neuron cell bodies working together in CNS
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tracts:
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bundles of axons in CNS
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nerves:
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bundles of axons in PNS
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white matter:
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myelinated axons
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gray matter:
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non-myelinated material
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