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24 Cards in this Set

  • Front
  • Back

Cellular Respiration

- Process by which cells acquire energy by breaking down nutrient molecules produced by photosynthesizers with the concomitant production of ATP (Includes aerobic and anaerobic respiration)


-Consumes O2 and produces CO2, opposite of photosynthesis


- Involves complete breakdown of glucose to CO2 and H2O, and energy to produce 36-38 ATP molecules


- Oxidation-reduction enzymes include NAD+ and FAD as coenzymes

C6H12O6 + 6 O2 => 6 CO2 + 6 H2O + energy




C6H12O6 Oxidizes to 6 CO2


6 O2 Reduces to 6 H2O

Cellular Respiration Equation




And which one is oxidized? Which one is reduced?

NAD+


( Nicotinamide adenine dinucleotide)

- Coenzyme of oxidation-reduction (Redox)


- Oxidized when it gives up electron


- Reduced when it accepts electrons and associated with hydrogen proton

FAD

- Redox Coenzyme, sometimes used instead of NAD+


- Accepts 2 electrons and 2 H+ to become FADH2

Glycolysis (Anaerobic)


Pyruvate Oxidation (Aerobic)


Citric Acid Cycle (Aerobic)


Electron Transport Chain (Aerobic)

4 Phases of Cellular Respiration GPCE

Aerobic

- Take place inside the mitochondria


- Oxygen is final acceptor of electrons


- Require oxygen

Glycolysis

- Breakdown of glucose (6C) to 2 pyruvate (3C)


- Glucose oxidation results in reduced NADH and provides enough energy for the net gain of 2 ATP molecules


- Takes place outside of mitochondria in cytoplasm and does not require oxygen (anaerobic)


- Energy investment and Energy payoff phase

Pyruvate Oxidation

- Inthe presence of O2, pyruvate enters matrix of the mitochondrion


- Pyruvate (3C) is oxidizes to acetyl CoA (2C) and CO2 [By a multienzyme complex that catalyses 3 reactions]


- NAD+ Reduces to NADH


- Occurs twice per glucose since there are 2 pyruvate

Citric Acid Cycle

- Takes place in the matrix of the mitochondrion


- Each (2C) acetyl CoA matches up with a (4C) oxaloacetate, forms (6C) citrate


- (6C) citrate oxidizes to reduce to 3 NADH and 1 FADH2, 2 CO2 per citrate are released


- Able to produce 1 ATP per turn to make 2


- 2 acetyl CoA enter cycle per glucose molecule, so cycle turns twice


[8 steps catalyzed by specific enzyme]

Electron Transport Chain

- Series of carriers on the cristae of the mitochondria


- NADH and FADH2 oxidizes to give up their high-energy electrons to the chain


- Energy is released and captured as the electrons move from a higher-energy to a lower-energy state during each redox reaction


- O2 receives electrons and combines with H+ to become H2O


- Energy from exergonic flow of H+ down ATP synthase used to drive phosphorylation of ATP into 32-34 ATP (chemiosmosis)

Chemiosmosis

- Term used to refer to the movement of hydrogen protons down its concentration gradient through the ATP synthase from the cristae to matrix to drive cellular work



Oxidative Phosphorylation

- Term used to refer to the releasing of electrons by oxidizing NADH and FADH2 to the electron transport chain for chemiosmosis


- Powers ATP synthesis

6 C Glucose


2 NAD+


2 ATP


4 ADP + 4 P




2 (3C) Pyruvate


2 NADH


4 ATP

Inputs of Glycolysis (4)




Outputs of Glycolysis (3)

Glycolysis - 2 ATP


Citric Acid Cycle - 2 ATP


ETC - 32~34 ATP

ATP Net yield per glucose by each stage

Inputs: Glucose [ 2 ADP + 2 P]


Outputs: 2 Lactate in animals and bacteria (Or 2 alcohol, 2 CO2 in plants/yeast) [2 ATP net gain from gycolysis]

Inputs and outputs of Fermentation

34%

Glucose is about 686Kcal and the energy yield of 36 ATP is about 263 Kcal.




Glucose metabolism is therefore only about ___ efficient and the rest of energy is lost as heat; rather inefficient.



2 (2C) acetyl CoA


6 NAD+


2 FAD


[2 ADP + 2P]




4 CO2


6 NADH


2 FADH2


[2 ATP]

Inputs of the Citric Acid Cycle (4)




Outputs of the Citric Acid Cycle (4)

Exergonic Reaction
- Reaction where there is a breakdown of organic molecules and releases heat
Fermentation
- Enables cells to produce ATP without O2, ETC ceases to operate

- Glycolysis couples with anaerobic respiration or this to produce ATP


- Partial degradation of sugars/organic molecules to regenerate NAD+, which can be reused by glycolysis


- Alcohol or lactic acid producing

Oxidation


Reduction

- Losing of electrons


- Gaining of electrons

Alcohol Fermentation

- Pyruvate is converted to ethanol in two steps


- First step releases CO2


- Second step produces ethanol


Ex: Yeast used in brewing, winemaking and baking

Lactic Acid Fermentation

- Pyruvate is reduced by NADH, forming this as an end produce, with no release by CO2


Ex: Fungi and bacteria can make cheese and yogurt; human muscles use this to generate ATP when oxygen is scarce

Cytochromes

Proteins that act as electron transfer agents in many metabolic pathways, especially cellular respiration

2 Pyruvate (From Glycolysis)




2 Ethanol




2 Lactate

Input of Alcohol Fermentation and Lactic Acid Fermentation?




Output of Alcohol Fermentation




Output of Lactic Acid Fermentation