B&b Quiz 4: Substance Abuse

Front 1

nucleus accumbens (NA)

Back 1

a small nucleus in the basal ganglia associated with addiction

Front 2

mesolimbic dopaminergic tract

Back 2

Dopaminergic neurons in the tegmentum of the brain stem that project to the nucleus accumbens and frontal cortex

Front 3

substance abuse

Back 3

Maladaptive pattern of substance use for 12+ months that leads to impairment of occupational, physical, or social functioning.

Front 4

substance dependence

Back 4

Substance abuse plus withdrawal symptoms, tolerance, or a pattern of compulsive use

Front 5

tolerance

Back 5

Need for increased amounts of the substance to achieve the same positive physical and psychological effects

Front 6

withdrawal

Back 6

Development of physical or psychological symptoms after the reduction or cessation of intake of a substance

Front 7

cross-tolerence

Back 7

Development of tolerance to one substance because of using another substance

Front 8

detoxification

Back 8

treatment of withdrawal symptoms of substance abuse

Front 9

alcohol

Back 9

The most commonly abused sedative psychoactive substance

Front 10

benzodiazepines

Back 10

Prescription sedatives used as anxiolytics and hypnotics.

Front 11

barbituates

Back 11

Prescription sedatives with high abuse potential. Used as hypnotics, though rarely any more.

Front 12

heroin

Back 12

Opioid with no legal therapeutic use, often used IV.

Front 13

prescription opioids

Back 13

the most commonly abused class of prescription drugs.

Front 14

amphetamines

Back 14

Prescription stimulants used in ADD and nacolepsy. They stimulate the release of dopamine.

Front 15

methamphetamine

Back 15

a powerfully addictive amphetamine derivative, referred to as "crystal meth"

Front 16

MDMA

Back 16

aka ecstasy. A synthetic street drug with amphetamine-like and hallucinogenic properties.

Front 17

cocaine

Back 17

Stimulant that blocks the reuptake of dopamine and has no legal therapeutic use

Front 18

caffeine

Back 18

Found in beverages, has mild stimulant effects and significant withdrawal sx

Front 19

nicotine

Back 19

Found in tobacco products, with mild stimulant effects and significant withdrawal sx

Front 20

marijuana/cannabis

Back 20

Substance with euphoric and mild hallucinogenic proprerties, which is legal for use as a thepeutic agent in some states

Front 21

hashish

Back 21

is a cannabis product composed of compressed or purified preparations of stalked resin glands

Front 22

THC-Tetrahydrocannabinol

Back 22

is the principal psychoactive constituent (or cannabinoid) of the cannabis plant

Front 23

amotivational syndrome

Back 23

syndrome associated with chronic marajuana use, characterized by decreased desire to work and increased apathy

Front 24

LSD-lysergic acid diethylamide

Back 24

Hallucinogenic street drug with no therapeutic indications. Serotonergic.

Front 25

PCP-phencyclidine

Back 25

aka Angel Dust. Hallucinogenic street drug with no therapeutic indications. Glutamineric

Front 26

Psilocybin

Back 26

aka shrooms. allucinogenic street drug with no therapeutic indications which is derived from mushrooms.

Front 27

Mescaline

Back 27

an abused hallucinogen derived from cactus, which has some societally condoned use in traditional Native American cultures.

Front 28

ketamine

Back 28

aka special K. hallucinogenic drug used in anaesthesia which has a glutaminergic effect.

Front 29

flumazenil

Back 29

benzodiazepine receptor antagonist used in the treatment of benzodiazepine overdose

Front 30

disulfram

Back 30

Tx to prevent alcohol use that blocks the breakdown of alcohol and results in acetaldehyde accumulation. Concomittent ingestion of alcohol results in intense nausea, headache, and flushing.

Front 31

naltrexone

Back 31

an opioid receptor antagonist used as a pharmacologic treatment of alcohol abuse that works by blunting the positive effects of alcohol

Front 32

naloxone

Back 32

opioid antagonist used in the treatment of opioid overdose

Front 33

MICA patients

Back 33

mentally ill chemically adicted patients

Front 34

CAGE questionnaire

Back 34

a frequently used screening tool used to identify patinets who may have alcohol abuse; have you tried to cut down on drinking, do you get angry when people ask about your drinking, do you feel guilty, do you ever need an eye-opener

Front 35

positive CAGE

Back 35

Yes to last question or 2 others

Front 36

delirium tremens

Back 36

Life-threatening alcohol withdrawal syndrome characterized by altered mental status. May also occur with benzodiazepine withdrawal. Seen on day 3 of withdrawal.

Front 37

treating DT

Back 37

fluids, thiamine, folate, glucose, benzos **lorazepam for pt w/ liver failure

Front 38

opioids OD

Back 38

manifests as coma, respiratory depression, miosis

Front 39

buprenorphine

Back 39

a mixed opioid agonist/antagonist approved for treatment of opioid addiction