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80 Cards in this Set
- Front
- Back
Bacillus cereus and anthracis; Clostridium - tetani, botulinum, perfringens, difficile |
Spore formers |
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These rascals may microscopically lack color - treponema, ricketssiae, mycobacterium, mycoplasma, legionella, chlamydiae |
Bacteria not seen in gram stain |
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Borrelia burgdorferi |
Largest medically significant bacteria |
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BLT - Borrelia, Lepstospira, Treponema |
Spirochetes |
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Superoxide dismutase, Catalase, Peroxidase |
Enzymes needed to survive aerobic environment |
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Tetanospasmin |
Protease that cleaves proteins involved in the release of glycine from Renshaw cells in spinal cord |
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Botulinum toxin |
Heat labile neurotoxin that blocks acetylcholine release causing descending pattern flaccid paralysis |
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Triad of Botulism |
Symmetric descending flaccid paralysis with prominent bulbar involvement, absence of fever, intact sensorium |
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Alpha toxin |
Lecithinase that cleaves cell membranes, contributing to gas gangrene |
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Clostridium difficile |
Exotoxin detected by cytopathic effect on cultured cells or ELISA; associated with suppression of normal flora by use of Clindamycin, 2nd and 3rd gen cephalosporin, ampicillin |
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Corynebacterium diphtheriae |
Chinese characters; with toxigenicity detected using modified elek test |
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Babes-Ernst granules/volutin granules |
Metachromatic granules in Corynebacterium diphtheriae |
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ShigA-like, Botulinum, Cholera, Diphtheriae, Erythrogenic toxins |
Beta prophage encoded toxins |
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Staph aureus |
Gram +, catalase +, coagulase + |
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Staph epidermidis |
Gram + catalase + coagulase - novobiocin S |
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Staph saprophyticus |
Gram + catalase + coagulase - Novobiocin R |
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Strep pneumoniae |
Gram +, catalase -, green/partial hemolysis, optochin S with capsule and bile soluble |
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Viridans streptococci |
Gram +, catalase -, green/partial hemolysis, optochin R, not bile soluble, no capsule |
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Strep pyogenes |
Gram + catalase - clear hemolysis, bacitracin S |
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Strep agalactiae |
Gram +, catalase -, clear hemolysis, Bacitracin R |
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Enterococcus |
Gram +, catalase -, no hemolysis, aerobe |
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Peptostreptococcus |
Gram +, catalase -, no hemolysis, anaerobe |
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Clostridium (anaerobic), Corynebacterium, Listeria, Bacillus |
Gram positive bacilli |
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Strep pyogenes: exotoxin B |
Facilitates necrotizing fasciitis |
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Strep pyogenes: erythrogenic toxin |
Causes scarlet fever: strawberry tongue, sandpaper like rash, Pastia's lines, desquamation |
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Strep agalactiae |
Most common cause of neonatal pneumonia, sepsis and meningitis; CAMP test +, grown in LIM broth |
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Strep pneumoniae |
MCC CAP, presenting with rust-colored sputum and lobar pattern; gram + diplococci with positive Quellung reaction |
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Some killers have pretty nice and sexy bodies: Strep pneumoniae, Klebsiella pneumoniae, Haemophilus influenzae, Pseudomonas aeruginosa, Neisseria meningitidis, Salmonella typhi, Group B strep |
Encapsulated bacteria |
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Strep pneumoniae |
MCC otitis media, sinusitis, bacterial meningitis |
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Strep mutans |
MCC of Dental caries |
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Strep sanguis |
MCC of subacute and native valve endocarditis |
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Strep intermedius |
Bacteria in brain abscess |
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Staph aureus |
MCC acute endocarditis |
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Waterhouse-Friderichsen Syndrome |
Most severe form of meningococcemia, with high fever, shock, widespread purpura, DIC, thrombocytopenia and adrenal insufficiency |
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Neisseria meningitidis |
MCC of meningitis among 2-18 year olds |
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Neisseria gonorrhoeae |
MCC of urethritis, PID and septic arthritis in sexually active adults |
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Fitz Hugh Curtis Syndrome |
Complication of PID causing violin string adhesions and perihepatitis |
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Haemophilis aphrophilus, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, Kingella kingae |
Organisms causing subacute infective endocarditis in patients with pre-existing heart disease |
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Haemophilus influenzae |
Satellite phenomenon around S. Aureus colonies; type B polyribitol phosphate = 95% invasiveness of this disease; affects children from 6mos to 1 year and is MCC of epiglottitis |
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Salmonella, Brucella, Mycobacterium, Listeria, Francisella, Legionella, Yersinia |
Facultative Intracellular Bacteria |
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Bordetella pertussis |
With filamentous hemagglutinin, pertussis toxin, false adenylate cyclase and tracheal cytotoxin |
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Escherichia coli |
Green sheen on EMB; with O and H antigens, HST and HLT enterotoxins and HUS-causing verotoxin; MCC of community acquired UTI, 2nd MCC of neonatal meningitis |
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Salmonella spp |
Widal test to detect antibodies in serum |
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Salmonella typhi |
Multiplies in peyer's patches then RES; predilection for gallbladder; presents with stepwise fever, abdominal pain, jaundice and hepatomegaly; incubation of 5-21 days |
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Shigella sonnei |
MCC of bacillary dysentery |
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Shigella dysenteriae |
MCC of epidemic dysentery and most severe form of bacillary dysentery |
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Campylobacter jejuni |
MCC of bacterial gastroenteritis; causes histologic damage to mucosa of jejenum |
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Reiter's syndrome |
Uveitis, urethritis, arthritis; this and Guillain Barre syndrome are associated with C. Jejuni infection |
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Klebsiella pneumoniae |
Currant jelly sputum; with ESBL activity; MCC of pneumonia in alcoholics |
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Pseudomonas aeruginosa |
MCC of otitis externa, malignant otitis externa in diabetics, CSOM; disease spectrum includes ecthyma gangrenosum and febrile neutropenia; with pyocyanin |
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Bacteroides fragilis |
Predominant anaerobe of human colon; with foul-smelling discharge and short chain fatty acids |
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Nosy and Nagging Pests Must Breathe Lots of MP: Nocardia, Neisseria, Pseudomonas, Bordetella, Brucella, B. cereus, Legionella, Leptospira, Mycoplasma pneumoniae |
Obligate aerobes |
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Mycoplasma pneumoniae |
Most common infectious cauae of SJS |
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SHiNe My Gong: Strep pneumo, Haemophilus Influenzae, Neisseria Meningitidis, Neisseria Gonorrhea |
Bacteria with IgA protease |
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Staphylococcal enterotoxin |
Only exotoxin that is not heat-labile |
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A, C, Y, W135 |
Strains of N. Meningitidis in meningococcal vaccine |
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Lipid A |
Toxic component of LPS that activates the complement and the coagulation cascades |
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Bacillus anthracis |
Box-car like gram + rods with edema toxin and lethal toxin |
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Bacillus cereus |
Gran positive rod with heat-labile and heat-stable enterotoxins causing diarrhea and emesis respectively |
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Clostridium perfringens |
Double hemolysis on blood agar, alpha toxin causes gas gangrene |
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Clostridium difficile |
Infections can precipitate flare-ups of ulcerative colitis |
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Listeria monocytogenes |
Tumbling motility with internalin and actin rockets; associated with ingestion of unpasteurized milk products |
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Eikenella corrodens |
MCC of human bite infection |
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Legionella pneumophila |
Causes atypical pneumonia and pontiac fever through aerosol from water source |
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Salmonella |
Produces H2S, Widal test detects antibodies in serum; infective dose 10^6 organisms |
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Vibrio spp |
Comma-shaped gram neg rods with shooting star motility with enterotoxin that activates Gs |
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Camylobacter jejuni |
Associated with GBS and Reiter's syndrome; produces watery foul-smelling diarrhea followed by bloody stools, fever and severe abdominal pain |
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Helicobacter pylori |
Damages goblet cells if gastric mucosa; detected via EGD and urease breath test |
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Particular kinds have urease: Proteus mirabilis, Klebsiella pneumoniae, Helicobacter pylori, Ureaplasma uralyticum |
Urease positive bacteria |
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Klebsiella pneumoniae |
Currant jelly sputum; MCC of pneumonia in alcoholics; |
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Proteus mirabilis |
Urease positive gram neg rod with swarming motility; forms struvite stones |
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Pseudomonas aeruginosa |
With pyocyanin and aninoacetophenone; MCC of otitis externa and CSOM; causes ecthyma gangrenosum and febrile neutropenia |
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Bacteroides fragilis |
Predominant anaerobe of the colon that spreads to blood or peritoneum during bowel trauma perforation or surgery |
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Brucella abortus |
Small gram neg rods without a capsule transmitted via contaminated dairy or direct contact causing undulated fever |
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Francisella tularensis |
From rabbits or deer; causes tularemia |
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Yersinia pestis |
Causes bubonic, pneumonic and septicemic plague through flea bite; gram negative bipolar staining |
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Pasteurella multicocida |
Gram neg rod that exhibits bipolar staining and butterfly colonies with musty odor; from animal bites |
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Mycobacterium tuberculosis |
Cord factor is its most important virulence factor; with Ghon's focus, Ranke's complex and Simon's focus |
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Actinomyces israeli |
Hard nontender swelling with sinus tracts draining sulfur granules |
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Nocardia asteroides |
Gram + rod with aerial hyphae and manifests as mycetomas and brain abscesses |