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61 Cards in this Set

  • Front
  • Back

Gastrointestinal tract (alimentary canal)

•Continuous tube open at both ends


• Function = digest and absorb nutrients


• Includes: Mouth,pharynx, esophagus, stomach, large intestine

Accessory organs

•Function = production of secretions that aid digestion, mastifucation of food


• Includes: Teeth, tongue, salivary glands, liver, gall bladder, pancreas

Basic 4 layers of tissue

1) Mucosa = Simple Columnar ET


2)Submucosa = Consists of areolar connective tissue


3)Muscularis = Smooth muscle


•Inner circular


•Outer longitudinal


4) Serosa = Connective tissue (outermost layer)

4 types of teeth

Incisors: Cut


Canines: Shred/Tear


Pre Molars: Grind


Molars: Grind

Mastication

Mechanical breakdown of food by teeth

Deglutition

Swallowing

Peristalsis

Radially symmetrical contraction/relaxation of muscles that propagates in a wave down a tube, in a forward direction beginning in the esophagus

Parotid gland location

Anterior to ear and external to masseter muscle

Function of paotid/sublingual/submandibular glands

•Produce secretions to dissolve food chemicals for taste


•Moistens food; compacts into bolus


•Begins breakdown of starch with enzyme salivary amylase

Salivary Amylase

Starts carb digestion



•lingual lipase = starts fat breakdown

Esophagus

•propels food to stomach where peristalsis begins


•Stratified Squamous epithelium


•Muscularis changes to smooth muscle


•Outer layer termed adventitia attaches esophagus to surrounding structured (trachea)

Stomach Mucosa: Mucus glands do what?

Secrete mucus for auto-protection from acidic gastric juices

Stomach Mucosa: Parietal cells

Secrete HCL to activate pepsinogen and kill bacteria ; and intrinsic factor

Stomach Mucosa: Chief cells

Secrete pepsinogen for protein digestion

Stomach Mucosa: Enteriendocrine Cells (G Cells)

Secrete Gastrin (hormone) that stimulates gastric juice secretion

Muscularis of stomach

Expands to 3 layers to churn foos and for peristalsis:



Inner oblique


Circular


Outer longitudinal

Chemical digestion of protein is done by...

Protein by pepsin

Gastrin(hormone)

Stimulates HCL release and thus the conversion of pepsinogen to Pepsin, and gastric churning

Only stomach function essential to life is...

Secretion of intrinsic factor for vitamin B12 absorption


•B12 needed for rbc maturity


•Lack of intrinsic factor causes pernicious anemia

Chime is

A semi-fluid mass of partly digested food that is expelled by the stomach

3 regions of the small intestine

Duodenum = contains hepatopancreatic sphincter (of Oddi) which regulates entry of bile and pancreatic secretions



Jejunum = contains cells that produce brush border enzymes; major absorption of nutrients



Ileum = contains ileocecal valve at large intestine to stop bacteria entering small intestine

Circular folds (plicae circularis)

Mucosa and submucosa folds that's slow down chyme movement to maximize absorption

Villi

Fingerlike mucosal projections that increase surface area



Contains lacteals(lipids) and capillaries for absorption

Microvilli (brush border) secrete...

Secrete carb and protein enzymes to complete digestion

Takes time to modify acidity =

Bicarbonate from pancreas neutralizes acid

Disaccharides

Maltase, sucrase, lactase



Complete carb digestion to monosaccharides

Dipeptides: dipeptidase does what?

Dipeptidase = completes protein digestion to amino acids

Liver receives blood from

Hepatic artery = O2



Hepatic portal vein = nutrients hormones, ect. From stomach, intestines, spleen, pancreas

Liver: at lobule corners you find

Portal triad = composed of Hepatic artery, Hepatic portal vein, bile duct

Sinusoids

Capillary like vessels that empty into central vein

Central veins

United to form Hepatic vein which empties into inferior vena cava

Liver function

•Process nutrients from small intestine


•synthesize plasma proteins


•detoxify alcohol and drugs in blood from stomach and SI


•store glucose as glycogen



Produce bile = alkaline solution containing bile salts and pigments; transports cholesterol out of body and conjugated bilirubin (RBC end products)



Bile = digestive aid - not enzyme = emulsify fat

Gall bladder location and function

Location = inferior surface of right liver lobe


Function = store and release bile

Hepatic duct

Carries bile to gall bladder

Cystic duct

Carries bile from gall bladder

Common bile duct does what?

Carries bile to duodenum

Pancreatic duct joins common bile duct to form __ which empties into duodenum through ___

Hepatopancreatic ampulla (of vater)


Hepatopancreatic sphincter (of Oddi)

Pancreas: Acini cells

Produce pancreatic juices

Pancreatic amylase

Breaks down starch to disaccharides

Pancreas: Trypsin, Chymotrypsin

Polypeptide to a dipeptide

Pancrease: Carboxypeptidase

Cleaves the carboxyl group off the end of the AA chain

Pancrease: Lipase

Breaks down triglyceride to glycerol and fatty acids

pancrease: DNAse, RNAse become

DNA and RNA to nucleotides

Pancrease: bicarbonate

Neutralize gastric juice in small intestine

Islets (of lamgerhans) cells

Produce insulin and glucagon

LI : Haustra

Sacs formed from smooth muscle bands

LI subdivisions

•Cecum = lies below ileocecal valve, contains appendix



●Colon


•Ascending colon


•Transverse colon


•Descending colon


•Sigmoid colon



•Rectum = anal sphincter at end to regulate defecation

Large intestine general functions

Very little food breakdown



Contains E.coli


•Produce vitamin B and K



Reabsorbs H2O electrolytes, fat soluble vitamins



Major Job = store and form feces

Gastrin

•Stimulus is food in the stomach


•Stimulates HCL release in the stomach

Secretin

•Stimulus is acidic chyme in the duodenum



•Stimulates release of bicarbonate when acidic (HCL) chyme enters intestine and bile



•Inhibits gastrin

CCK (Cholecystokinin)

•Stimulus is fatty chime in duodenum



•Targets hepatopancreatic ampulla and sphincter to relax



•Stimulates release of pancreatic enzymes and bile to be secreted into S.I.

Chemical digestion occurs by....

Hydrolysis

Must digest all foods into simplest unit for absorption:

Carbs = monosaccharides


•Proteins = amino acids


•Lipids = triglycerides (fatty acids and glycerol)


•Nucleic acids = nucleotides

Salivary amylase is _____ in stomach by HCL

Denatured

Lipid digestion occurs predominantly in

Small intestine

Bile salts from liver emulsify fat =

Increase surface area of lipids exposing bonds

DNAse and RNAse from pancrease digests DNA and RNA into...

Nucleotides

Most absorption occurs before...

Ileum

The ileum absorbs bile salts and...

Recycles them to liver

Monosaccharides, amino acids, nucleic acids absorbed into...

Capillaries

Fatty acids,glycerol, triglycerides absorbed by _____ enter lymph system, renters blood by heart

Lacteals