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142 Cards in this Set

  • Front
  • Back

Largest living structure on Earth and it's size

Great Barrier Reef of Australia. 2,600km/133,000 sq/ miles

How many cells make up the body

75 to 100 trillion

All cells are derived from a single cell known as a

Zygote

Characteristics Shared by All Living Things



Organization

Living things are highly organized and expend a large amount of energy to maintain order

Characteristics Shared by All Living Things



Metabolism

Chemical reactions occurring in cells


Organisms acquire energy from their environment


Use energy to maintain internal order

Characteristics Shared by All Living Things


Homeostasis

Maintenance of relatively stable internal conditions



P.h. of blood is maintained by homeostasis.

Characteristics Shared by All Living Things



Respond to Stimuli

Organisms react to environmental changes that promote their survival

Characteristics Shared by All Living Things


Growth

Produces more or larger cells

Characteristics Shared by All Living Things


Development

Series of changes in state of a cell, tissue, organ, or organism.

Characteristics Shared by All Living Things


Reproduction

Produces organisms with defined set of characteristics.


Organisms reproduce to sustain life over many generations.


DNA provides blueprint for the organization, development, and function of living things.

Characteristics Shared by All Living Things


Adapt and Evolve

Evolution: Change in Allele frequencies in populations of organisms over time.


Pesticide resistant insects


Antibiotic resistant bacteria

Bacteria

Most primitive cells


Lack a nucleus


Have cell wall (outside of plasma membrane)

Archaea

Cells lack a nucleus


Have cell wall


Some live in extreme environments

Eukarya

Cells have a nucleus

Protista

Most are single celled organisms


Autotrophic or Heterotrophic


Usually no cell wall

What is science?

Observation, identification, experimental investigation, and theoretical explanation of natural phenomena.

What is the scientific method?

The general method used by scientific investigators to gather information about the natural world. Every reputable investigator adheres to this method.

Steps in the scientific method

1. Observation


2. Hypothesis


3. Design an Experiment (control group and experimental group)


4. Collect data


5. Draw a conclusion (hypothesis is supported or rejected).


6. Theory formation

Analyzing graphs

results plotted on Y axis


experimental value is plotted on X axis

What is standard error?

The statistical information that tells us how certain a particular variable is.

Define an Atom

Smallest unit of matter indivisible by normal chemical and physical means.


Can divide by chemical measures

Molecule

Two or more atoms joined together.

Cell

Smallest unit of life

Organelle

Compartmented regions of cytoplasm where specific reactions occur.

Species

Similarly constructed organisms capable of producing fertile offspring.

Population

All members of the SAME SPECIES living in a specific location.

Community

All of the members of different species living in a specific location.

Ecosystem

Composed of the living and non-living components of a given area.

Biosphere

The region above, on, and below the earth's surface capable of sustaining life.

How many atoms make up the human body?

At least 7 octillion

These chemicals make up over 90% of the human body

Hydrogen, Oxygen, Carbon, and Nitrogen

Matter

Anything that has a mass and takes up space

Elements

Basic building blocks of matter. Composed of the same type of atom.

Atomic symbol

Shorthand method for representing an element.

Atomic Number

Number of protons an atoms contains

Atomic Mass

Sum of the number of protons and neutrons in an atom

Proton

Positively charged subatomic particle


Located within the nucleus.

Neutron

Subatomic particle with no charge


Located within the nucleus

Electron

Negatively charged subatomic particle.


Atoms have the same number of protons as electrons.

Isotope

Atoms of the same element with same number of protons but a different number of neutrons.

Molecules

Forms when two or more atoms join together.


Can be made of the same atom or different atoms.

Octet Rule

Atoms most stable with eight electrons in outermost shell. (Exceptions is Hydrogen with only one shell and is full with only two electrons).

Ionic Bonds

Gain or loss of electrons that results in net electrical charge of an atom.


Not very strong bonds


A charged atom is an Ion.

Cations

Positively charged ions

Anions

Negatively charged ions.

Covalent Bonds

Strong bonds


Atoms share electrons


Electro-negativity: The ability of atoms to attract electrons in a bond with another atom.


Represented by a solid line.

Non-polar Covalent Bonds

Electrons are shared equally


No partial charges develop on atoms


Polar Bonds

Separation of charges in resulting molecule


Electrons are not shared equally


One atom "tugs" electron closer to it's nucleus.

Hydrogen Bonds

Weak chemical attraction b/w a partially positive atom of a polar molecule and a partially negative atom of another polar molecule.


Individually weak bonds.

Water

Solvent that serves as the medium in which chemical reactions occur.


Water molecules cling together


High Heat of Vaporization


Able to absorb heat without increasing much in temperature.

Acid

Releases hydrogen ions in solution

Base

Releases hydroxyl ions in solution

pH scale

Measure of H+ concentration of a solution.


pH can affect:


Shape and Function of Molecules


Chemical reaction rates


Ability of molecules to bind together


Ability of ions/molecules to dissolve in water.

Acidic Solution


Basic Solution


Neutral Solution

Acidic: pH<7


Basic: pH>7


Neutral: pH=7

Salt

Forms when an acid and base react

Buffer

Prevents drastic changes in pH of body fluids.

Organic molecules

Composed of carbon atoms in the form of chains or rings and also contain hydrogen.

4 Organic Macro-molecules of Life

Carbohydrates (starches/sugars)


Proteins


Lipids (fats)


Nucleic Acids

Carbohydrates

Sugars and Starches


Function:


Energy sources


Structural Elements


Recognition sites on membrane surfaces


Contain 1 C, 2 H, 1 O


Monosaccharides

Simple Sugars


Contain monomers (building blocks)


Contain glucose (fuel molecule burned to make quick energy) Ex: Fructose

Disaccharides

Polymers of mono-saccharides


2 mono-saccharides joined


Contain sucrose (table sugar)


Contain lactose (milk sugar)

Polysaccharides

Polymers of monosaccharides


Long chains of monosaccharides


Contains Glycogen (branched)--Primary storage form of glucose in animals


Contains Cellulose (unbranched)--Primary storage form of glucose in plants

Proteins

Composed of 20 commonly occurring amino acids (monomers).


Functions:


Structural Elements


Transport of Molecules and Ions


Enzymes (speed up chemical reactions and required to maintain homeostasis)


Defense of the body


Cell Signaling


Gene Expression and Regulation

Lipids

Fats and fat-like substances


Will not dissolve in water


Functions:


Primary component of biological membranes


hormones (testosterone, estrogen)


energy sources


body contour (adipose) and insulation (guards against excessive heat loss)

Triglycerides

Composed of glycerol and 3 fatty acids


Burn as fuel molecules to help meet long-term energy needs


Saturated Triglycerides

Each C in fatty acid is attached to 2 H atoms


Solid @ room temperature


Butter, lard, margarine

Unsaturated Triglycerides

Double bonds between some C atoms in fatty acid


Tend to be liquid @ room temperature


Corn oil, Sunflower Oil

Phospholipids

Primary component of membranes


Resemble triglycerides with one fatty acid replaced by a phosphate group


Phosphate group is charged :Head (polar)


Remainder of molecule is not charged: Tail (non-polar)

Steroids

Alcohols with fat-like properties


Composed of 4 fused carbon rings


Examples are:


Cholesterol


Testosterone


Estrogen


Progesterone


DNA (Deoxyribonucleic Acid)

Storage of all information required for protein synthesis; repository of genetic information.

Ribonucleic Acid (RNA)

Transcription (copying) of code in DNA and translation of the code (protein synthesis).

Carbon

Can form bonds with many other atoms.


Can form strong stable bonds with other carbon atoms.


Distance b/w carbon atoms is short


Shorter bonds more stable than longer bonds

Levels of Protein Organization (4)


Primary Structure


Secondary Structure


Tertiary Structure


Quaternary Structure

Primary Structure: Linear sequence of amino acids. Genetically determined.



Secondary Structure: Folding or pleating of the primary structure.



Tertiary Structure: Involves 1 polypeptide bending and folding of the secondary structure.



Quaternary Structure: Association of multiple polypeptides

What is the cell range size?

1 to 100 micrometers

Size of average human cell

50 micrometers or 0.05mm in diameter

Why are cells made up of many tiny cells instead of fewer larger cells?

When a cell increases in size, the volume (contents) of the cell increase at a higher rater than the surface area.

Prokaryotic Cells

Most primitive cell type. No nucleus or membrane bound organelles.

Archea

Can live in diverse environments.

Eukaryotic Cells

Nucleus containing the genetic material (DNA).


Have membrane bound organelles.

Organelles of Eukaryotic Cells



Plasma Membrane

Composed of a phospholipid bi-layer and proteins.


Regulates movements into/out of cell


Selectively permeable

Organelles of Eukaryotic Cells


Nucleus

Part of endomembrane system


Storage of genetic information (DNA)


Usually large 10-20% of cell volume

Part of nucleus


Chromatin

DNA and Protein


When condensed called chromosomes

Part of nucleus


Nuclear Envelope

Double membrane


Defines boundaries of nucleus


Part of endomembrane system


Part of nucleus


Nuclear Pores

Allow molecules to pass into/out of nucleus

Part of nucleus


Nucleolus

Ribosomal components made here

Organelles of Eukaryotic Cells


Endoplasmic Reticulum

Rough ER: System of membranes


Studded with Ribosomes (protein synthesis)


Functions: Protein synthesis and attachment of sugars to proteins & lipids (aka, glycosylation).



Smooth ER: Continuous with Rough ER


Lacks ribosomes


Functions: Lipid synthesis and detoxification

Organelles of Eukaryotic Cells


Golgi Apparatus

Part of endo-membrane system


Stack of membranes


Receives material from ER


Functions: Sorts, modifies and packages ER products


vesicle formation

Organelles of Eukaryotic Cells


Vesicle

Part of endo-membrane system


Membrane bound sac


Function: Storage/transport, detoxification, and digestion.

Lysosome

Digest worn-out cells parts, pathogens, and debris.


Contain hydrolytic enztymes

Cytoskeleton

Microtubules: Long, hollow, cylindrical structures.


Composed of protein tubulin


Maintain cell shape, movement, and organelles and chromosomes



Intermediate Filaments: Mechanical strength


Maintain cell shape.



Actin Filaments: Maintain cell shape


Movement

Mitochondrion

Power house of the cell


Site of ATP synthesis (inner-membrane)


Double membrane


Self-replicating


Mitochondrial DNA

Centriole

Composed of microtubules, separation of chromosomes during division.

Flagella

Composed of mictrotubules


Usually long and singular


Movement of entire cell (requires ATP

Cilia

Compose of microtubules


Usually short and multiple


In humans, move material across cells

Adhering Junctions

Join plasma membranes of adjacent cells together.


Cytoskeletal elements extend from one cell to the next.


Anchor cells together


Common in skin cells


Two types:


Zonula Adherent (adhesion junction and wrap around cell in belt like fashion)


Desmosome (spot welds, small circular junctions).

Occluding Junctions

Prevent material from passing between adjacent cells. Forms a seal b/w cells


Zips cells together


Common in Kidney


Type of this junction:


Zonula Occludens "tight junctions". Wrap around cell in belt like fashion.

Communicating Junctions

Allows material to pass from cell to cell.


Type:


Gap Junction (small circular complexes,forms channels b/w adjacent cells).

How things move across the plasma membrane:

1. Diffusion


2. Osmosis


3. Facilitated Transport


4. Active Transport


5. Endocytosis


6. Exocytosis

Diffusion

Random movement of molecules from a higher concentration to a lover concentration.


No energy required.

Osmosis

Diffusion of water molecules across a selectively permeable membrane.


Higher concentration to lower concentration


No energy required


Fluids may be able to alter the shape of cells

Isotonic fluids

Have sole solute concentration as water concentration. No net movement of water.


Cell shapes no altered.

Hypotonic fluids

Have lower solute concentration and higher water concentration than cells. Water enters cells. Cell may swell and burst. Ex: Distilled water.

Hypertonic fluids

Have higher solute concentration and lower water concentration than cells. Water leaves cells.


Cells shrivel (crenate). Ex: Sea water.

Tonicity

Ability of a fluid to change cell shape by altering water content.

Solute

Particles dissolved in a fluid.

Solvent

Fluid in which the solute is dissolved.

Facilitated Transport

Transport of molecules requiring a carrier protein


Molecules moved from higher concentration to lower concentration.


No energy required.

Endocytosis

Transports molecules or cells into the cell.


Plasma membrane invaginates around material


Vesicle forms and is incorporated into cell.

Exocytosis

Transport molecules out of the cell.


Vesicle containing molecules fuses with plasma membrane.


Vesicle opens releasing contents.

How much dust does dead skin in the atmosphere make up?

1 billion tons

How many skin cells per minute does a person shed

50,000

What is the span, weight and number of blood vessels contain in an adult's skin?

21 square feet, weighs 9 pounds, and contains > 11 miles of blood vessels.

How much seat per day does skin release in hot weather?

3 gallons

Tissues

Groups of similar cells working together to perform a specific function.

4 basic types of cells

1. Epithelial


2. Connective


3. Muscle


4. Nervous

Epithelial Tissue

Two types: Epithelium


Glandular Epithelium

Epithelium Tissue

Cover body surfaces and line body cavities


Function:


Secretion


Absorption


Protection

Glandular Epithelium

Derived from epithelial tissue


Contains:


Exocrine Glands--Equipped with ducts to transport product


Endocrine Glands--Ductless Glands. Highly vascular, product (hormones) transported by blood

Connective Tissue

Cartilage, bone, fat, etc.


Function:


Bind tissues, structures together (Ex: tendons/ligaments)


Protection


Support (bones of skeleton)


Insulation of body (adipose tissue)


Transport of vital materials (blood)

Connective Tissue


Cells

Fibroblasts---Most common, secrete matrix and fibers


Macrophages--Engulf debris


White Blood Cells--Defend body from disease


Plasma Cells--Secrete antibodies

Fibers

Secreted by fibroblasts


Collagen Fibers--Imparts great tensile strength to tissues


Elastic Fibers--Responsible for elasticity of tissue


Reticular Fibers--Structural framework for liver, lymph organs

Extracellular Matrix

Gel like consistency


Prevents invasion by bacteria


Allows water soluble materials to diffuse through


Types of muscle tissue

Skeletal (most attached to skeleton)


Cardiac (Heart)


Smooth (Walls of organs/glands)

Neuron

Only cell in nervous system capable of conducting nerve impulses.


Structural and functional unit of nervous system.

Integumentary System

Functions:


Protection


Prevention of Water Loss


Regulation of Body Temperature


Excretion of Waste Products


Synthesis of Vitamin D


Sensory Reception

Epidermis

Outer layer of skin


Composed of epithelial tissue

Types of Skin Cells

1. Keratinocytes


2. Melanocytes


3. Merkel Cells


4. Langerhan Cells


5. Dermis

Keratinocytes

Most common


Produce Water insoluable protein (keratin)


Arranged in 4 zones in thick skin


1. Stratum Basale: Inntermost layer of epidermins, single layers of living cells.


2. Stratum Spinosum: Next layer up. Spiny shaped living cells.


3. Straum Granulosum: Mixture of live and dead cells.


4. Stratum Lucidum: Only seen in thick skin, cells are dead.


Melanocytes

Produce pigment/melanin (black, brown, yellow)


Protects DNA from damage by UV light


Beta Carotene: Derived from diet--yellow orange. Stored in adipose tissue (fat)


Hemoglobin: Located in red blood cells, O2 transporting protein is Bright Red but pink when combine with O2

Merkel Cells

Touch receptors (b/w epidermis and dermis). Ex: Fingertips

Langerhan Cells

Defensive cells


Protection from disease causing agents

Dermis

Inner layer of skin


Highly vascularized


Contains sensory structures, lymph vessels, nerves, glands

Sensory Structures of the Dermis

Meissner's Corpuscles--Light touch (finger tips)


Pacinian Corpuscles--Deep pressure (large, look like an onion cut in half).

Hypodermis

Lies beneath dermis


Not a layer of the skin


Contains much adipose (fat) tissue


Function. Body contour, insulation


Females have a thicker layer of adipose tissue than males.

Glands

Derived from epithelial tissue

Sweat Glands

Eccrine: 2.5 million in the body. Function in temperature regulation


Apocrine: Function in humans is unknown. No role in temperature regulation.

Sebaceous Glands

Oil Glands


All regions of the body except for the palms and soles have these.


Large on face, neck, and upper chest. Produce sebum which lubricates skin and hair.


Clogged ducts with bacterial invasion is know as ACNE.

Hair Follicles

Organs that produce hair

Hair

Dead, Keratinized cells


Dark hair color is due to melanin production


If melanin contains iron and sulfur blonde or red hair results.


Gray hair has a lack of melanin


White hair is when air is trapped in hair shaft.

What causes goose pimples?

Contraction of arrector pili muscles


These attach to the hair follicles causing the hairs to contract and "stand on end"

Nails

Protective covering of distal part of fingers and toes.


Grows from special epithelial cell @ base of nail known as the nail root.

Lunula

White colored half moon shape at the nail based that results from the thick layers of cells there.


As nail grows over the nail bed it hardens becoming karatinized.