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101 Cards in this Set

  • Front
  • Back
What does CNS stand for?
Central nervous system
What does PNS stand for?
Peripheral Nervous System
What does the CNS include?
The brain and spinal cord
What does the PNS include?
cranial nerves, spinal nerves, ganglia, skin, and enteric plexuses
What organ contains the most receptors?
the skin
What does ENS stand for?
Enteric Nervous system
Where can you find the enteric plexuses?
In the small intestine
What are the 3 types of neurons in terms of their function?
1-sensory neurons
2-Motor neurons
3-Intermediate/relay/interneuron
Where are the intermediate/relay/interneurons usually found?
In the CNS
What are the afferent neurons?
sensory neurons
What type of functional neuron is this?
Motor neuron
Which neurons are efferent?
Motor neurons
Define Ganglia
Collections of neuron cell bodies
What is the ratio of neuroglia to cell bodies?
1 cell body for every 9 neuroglia
Define neuroglia
Nervous system cells
Define a bipolar neuron
There is one dendrite and 1 axon
What is another name for neuroglia?
Glia
Define a multipolar neuron
There is one axon and several dendrites attached to cell body
define unipolar neuron
Have dendrites and one axon that are fused together
Where would you find multipolar neurons?
in the brain and spinal cord
Where would you find bipolar neurons?
in the retina of the eye, in the inner ear, and in the olfactory area of brain
Where will you find Purkinje cells?
in the cerebellum
Where will you find pyramidal cells?
in the cerebral cortex of the brain
What are the 4 functions of astrocytes?
1- Maintain blood-brain barrier
2-Create 3-D framework for CNS
3-Perform repairs guiding neuron development
4-Control composition of extracellular fluid
What is the function of Olgiodencytes?
Myelination of neurons in the CNS
What is the purpose of myelination of neurons?
it insulates the neuron
Define Microglia
Specialized immune cells of the CNS
What are the 2 functions of ependymal cells?
1-to line the chambers and passage filled with CSF
2-to assist in the circulation of CSF
What is the function of Schwann cells?
Myelination of neurons in PNS
What does "gray Matter" represent?
Unmyelinated regions of the brain or spinal cord
What does "White Matter" represent?
Myelinated regions of the brain or spinal cord
What is the difference in how the gray and white matter is distributed in the spinal cord and the brain?
Spinal Cord: Gray matter is central
Brain: White matter is cenral
Define Driving Force
Natural tendency of flowing to and from cell body by concentration gradient
What are the 4 types of membrane channels?
1-Leakage Channel
2-Voltage-gated Channel
3-Ligand-gated Channel
4-Mechanically-gated ion Channel
Define Voltage-gated Channel
It responds to a direct change in membrane potential
When is an active transporter used as a bilayer channel?
If ions are needing to go against the natural flow
When is a passive transporter used as a bilayer channel?
If ions just need a passageway to flow through
At resting potential, what charge does the intermembrane of the excitable cell have?
Negative
At resting potential, what charge does the outermembrane of the excitable cell have?
Positive
Define Ligand-gated Channel
Channel that opens and closes in response to chemical messenger stimulus by binding to the gate to open it.
Define Ligand
Chemical messenger that results in neuron excitability
What are the two ways that axonal transport happens?
1-Slow Axonal Flow
2-Fast Axonal Flow
Explain what happens with slow axonal flow
1-movement is in one direction: away from cell body
2-moves only 1-5 mm a day
Explain what happens in fast axonal flow
1-movement of organelles and materials along surface of microtubules
2-moves at 200-400 mm a day
3-Transports in either direction
What is the Leakage channel mostly used for?
Much more of Potassium(K) than for Sodium(Na)
What does the Ligand-gated channel respond to?
a specific chemical stimulus
What does a mechanically-gated channel respond to?
a mechanical vibration or pressure
what are the structures called that are between axons?
Nodes of Ranvier
What are the 3 "types" of axons?
Type A
Type B
Type C
Which is the fastest type of axon?
Type A
Which is the biggest type of axon?
Type A
Which is the unmyelinated axon?
Type C
Which is faster, continuation or saltatory conduction?
saltatory
Define Agonist
Anything that enhances a transmitter's effects; Excites
Define Antagonist
Anything that blocks the action of a neurotransmitter; inhibits
When the word "potential" is said, what other word should come to mind?
Voltage
Is CO an antagonist or agonist?
antagonist
Define Synapse
Gap between cells
Which type of channel is necessary to respond to neurotransmitters?
Ligand-gated channels
What type of messenger is the neurotransmitter?
chemical messenger
Define Receptors
Structures to which chemical messengers combine in a lock and key fashion
Define Bind (in reference to the synaptic nerve)
The act of a chemical messenger occupying the binding site of a receptor
Define reuptake
(endocytosis) A mechanism used to take extra neurotransmitter back to presynaptic cell
What is the potential energy difference at resting potential?
-70mV
Give 2 reasons why resting membrane potential exists
1-Concentration of ions is different inside then it is outside
2-Membrane permeability differs for sodium and potassium.
How much greater is potassium's permeability than sodium's?
50-100 times
Define Hyper-polarization
the membrane has become more negative than at resting potential
Define Depolarization
The membrane has become more positive than at resting potential
Finish the sentence: There is a direct relationship between the strength of the stimulus and the__ _ __ ____ ___
size of the voltage change
Where do graded potentials occur most often in the neuron?
in the dendrites and cell body of the neuron
Define Action Potential
A series of rapidly occurring events that change and then restore the membrane potential of a cell to its resting potential.
What is the phase called when ion channels open and sodium rushes in?
Depolarization
What is the phase called when ion channels open and potassium rushes out?
Repolarization
What are the 2 gates in the sodium channel?
1-activation gate
2-deactivation gate
During the resting state which gates are open?
neither. Both are closed.
During the depolarization phase, which gates are open?
The sodium gate is open.
During Repolarization phase which gates are open?
potassium gate is open.
Which gates are open while repolarization phase is continuing?
neither. Both are closed.
What are the 2 types of refactory periods?
1-Absolute refactory period
2-Relative refactory period
What happens if an absolute refactory period happens?
another activation can't happen
What happens is a relative refactory period happens?
The inactivation gate is open and the cell is ready to fire again.
What tool gets the state back to resting potential?
the sodium/potassium pump
Define Spatial Summation
When the post-synaptic neuron receives chemical messages from pre-synaptic neuronS
Define Temporal summation
the times that a presynaptic neuron gives bursts to post-synaptic neuron.
Define EPSP
Excitatory post synaptic potential.
Define Excitatory Post Synaptic Potential.
Depolarizing post-synaptic potential that results from the opening of a ligand-gated sodium channel(s)
Define IPSP
Inhibitory Post Synaptic Potential
Define Inhibitory Post Synaptic Potential
Results from the opening of ligand-gated Cl- or K+ channels
What are the 4 different potential circuits?
1-Diverging
2-Converging
3-Oscillatory or reverberating
4-Parallel after-discharge
Explain a converging circuit
One cell is stimulated by many others
Give an example of a converging circuit seen in the body
the bipolar cells of the eye converging unto ganglion cells
Explain Diverging circuit
A single cell stimulates many others
Give an example of a diverging circuit seen in the human body
In visual circuitry (the eyes)
Explain Oscillatory or reverberating circuit
Impulses from later cells repeatedly stimulate early cells in the circuit.
Give a couple of examples of reverberating or oscillatory circuits seen in the body
1-waking
2-sleeping
3-short-term memory
4-breathing
Explain Parallel after-discharge circuits
A single cell stimulates a group of cells that all stimulate a common post synaptic cell
When would you use a parallel after-discharge circuit?
When attempting a math problem.
If a nerve is damaged, which part of the nerve is usually the damaged part?
the axon
How far does retrograde degeneration extend?
to the first neurofibril node
Define Wallerian Degeneration
Degeneration of the distal portion of the axon and myelin sheath
Define Chromatalysis
Break down of Nissl bodies into fine granular masses