Complications Of Acetylcholinesternase (Ache)

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There are billions of neurons in our brain that sends signals from the axon to the spinal cord. In the spinal cord the axon on will send signals to many neurons from other cells and then it will generate an order. The membrane potential is an electrical state of the cell membrane and it allows gradients that cause ions to move across the cell membrane. The dispersal of charge across the cell membrane is measured in (mV). The resting membrane potential is the difference between the charges inside and outside the sarcolemma. The intracellular concentration consists of sodium (Na+), potassium (K+), and Chlorine (Cl-). The concentration of potassium is high inside the cell and the concentration of sodium outside is high. The ion channels are …show more content…
The nervous membrane is an all-or-none event due weak stimuli that does not reach threshold and does not produce an action potential. Developmental and learning studies have also shown that the threshold adapts to slow changes in input characteristics (Platkiewicz J, Brette R (2010). The action potential will always have the same amplitude and duration. Acetylcholinesternase (AChE) is an enzyme that breaks down Ach and make sure there is no muscle contraction. Propagation is when depolarization spreads in adjacent areas and continues down the sarcolemma. The propagation reaches the T-tubules and terminal cisternae and the calcium is released into the sarcoplasm. The next step is repolarization and that is when the sodium channels close and the potassium channels open. The sodium potassium pump moves sodium and potassium in to restore the resting membrane potential (Michael, Cryder). The resting membrane potential becomes negative again. There is less sodium moving into the cell and more potassium moving out of the membrane …show more content…
The membrane potential is negative and all the potassium channels are closed due to the repolarization of potassium. The absolute refractory period occurs during repolarization and the muscle fibers cannot respond to a stimulus. The cell can regenerate anther action potential, but only id it is depolarized to a value more positive than the normal threshold. After the action potential is generated at the axon hillock it is then propagated down the axon. The other step is the action potential travels down the T-tubules. Then the action potential triggers the terminal cisternae to release calcium ions into the sarcoplasm. In sliding filament mechanism of contraction the relax state is when ATP binds to the myosin head and is cleaved into

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