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56 Cards in this Set

  • Front
  • Back

Total Body Water (TBW)

The sum of fluids within all body compartments. About 60% of body weight in adults.

Intracellular Fluid (ICF)

All fluid within the cells. About 2/3 of TBW.

Extracellular Fluid (ECF)

All fluid outside the cells. About 1/3 TBW. Includes interstitial fluids and intravascular fluids.





Interstial Fluids

Fluid in the space between the cells and outside the blood vessels.



Intravascular Fluid

Blood plasma



Sodium, chloride, potassium, and calcium



The most prominent electrolytes and solutes in ECF.

Phosphates and Magnesium

The most prominent electrolytes and solutes in ICF.

Starling Forces or net filtration

The 4 forces that determine if fluid moves into or out of capillary spaces.

Capillary Hydrostatic Pressure (Blood Pressure)

facilitates the outward movement of water from the capillary to the interstitial space.

Capillary (plasma) Oncotic Pressure


osmotically attracts water from the interstitial space back into the capillary


Interstitial Hydrostatic Pressure

facilitates the inward movement of water from the interstitial space into the capillary.

Interstial Oncotic Pressure

osmotically attracts water from the capillary into the interstitial space.

Aquaporins

A family of water channel proteins that provide permeability to water.

Sodium

Maintains ECF osmotic balance



Potassium

Maintains ICF osmotic balance

ADH (vasopressin)

primary regulator of water balance in the body

Aldosterone

regulates sodium concentration in the body

Renin

stimulates Angiotensin I, which stimulates Angiotensin II, which stimulates ADH and aldosterone who are vasoconstrictors.



Natriuretic Peptides

Hormones primarily produced by the myocardium. Antagonist to the renin- angiotensin-aldosterone system.

Chlorine

Anion in the ECF that provides electroneutrality, particularly in relation to sodium.



Osmoreceptors

Cause thirst and signal the posterior pituitary to release ADH. Triggered by increased osmality due to water deficit or sodium excess

Baroreceptors

Nerve endings that are sensitive to changes in pressure.

Hypertonic

Imbalances that result in ECF concentrations greater than 0.9% salt solution; causes cells to shrink


Hypotonic

Imbalances that result in ECF concentrations less than 0.9% salt solution; causes cells to swell

Isotonic Alterations

Occur when TBW changes are accompanied by proportional changes in the concentrations of electrolytes

Isotonic Fluid Loss

Symptoms are weight loss, dryness of skin and mucous membranes, decreased urine output, and symptoms of hypovolemia

Hypovolemia

Symptoms are rapid heart rate, flattened neck veins, and normal or decreased blood pressure

Isotonic Fluid Excess

Symptoms are decreased hematocrit, decreased, decreased plasma protein, edema, increased blood pressure, distended neck veins, and weight gain

135mEq/L - 145mEq/L

Normal range for sodium levels

Hypernatremia

Symptoms are thirst, weight gain, bounding pulse, hypertension, hyperflexia, confusion, coma, convulsions, and cerebral hemorrhage

Hyponatremia

Symptoms are low hematocrit, cerebral edema, increased intracranial pressure, depressed reflexes, n/v, weakness, hypotension, tachycardia, weight gain, ascites, and jugular vein distention

Hyperkalemia

Dysrhythmias,, peaked T waves, absent P wave with widened QRS complex, bradycardia, heart block, cardiac arrest, anxiety, tingling, numbness, n/v/d, colicky pain, oliguria, kidney damage

3.5 mEq/L - 5.0 mEq/L

Normal ECF concentration levels of potassium

Hypokalemia

Dysrhythmias, flattened T waves, U waves, peaked P wave, cardiac arrest, weak pulse, lethargy, fatigue, confusion, parasthesias, n/v, decreased bowel sounds, thirst, weakness, bladder dysfunction, respiratory distress

Metabolic Acidosis

concentrations of non-carbonic acids increase or bicarbonate is lost from extracellular fluid or cannot be regenerated by the kidney

metabolic acidosis

Symptoms are ha, lethargy, hyperventilation, anorexia, n/v/d, abdominal discomfort, dysrhythmias, diarrhea

metabolic alkalosis

When excessive loss of metabolic acids occur and bicarbonate increases

Metabolic alkalosis

Symptoms include weakness, muscle cramps, hyperactive reflexes, tetany, confusion, convulsions, shallow and slow respirations, and atrial tachycardia

Respiratory acidosis

When there is alveolar hypoventilation resulting in increased carbon dioxide in the blood

Respiratory acidosis

Signs and symptoms are ha, blurred vision, breathlessness, restlessness, and apprehension followed by lethargy, disorientation, muscle twitching, tremors, convulsions, and coma. Respirations are tachy at first and then become depressed. The skin may be warm and flushed.

Respiratory alkalosis

Occurs when there is respiratory hyperventilation resulting in decreased amounts of carbon dioxide in blood.

Respiratory alkalosis

Symptoms are dizziness, confusion, tingling of extremities, convulsions, coma, cardopedal spasm, tetany, and cerebral vasoconstriction

Calcium

Normal lab value 8.8 - 10.5 mg/dl
Hypocalcemia
Symptoms are intestinal cramping, hyperactive bowel sounds, tingling and muscle spasms particularly in hands, feet, and facial muscles

Hypercalcemia
Symptoms are bone pain, osteoporosis, lethargy, weakness, nausea, anorexia, constipation, impaired renal function, and dysrhythmias

Phosphate
Normal lab value 2.5-5.0 mg/dl
Hypophosphotemia
Reduced capacity for O2 transport by red blood cells, leukocyte and platelet dysfunction, deranged nerve and muscle function
Hyperphosphotemia
Symptoms primarily related to low calcium levels, when prolonged calcification of soft tissues in lungs, kidneys, and joints

Magnesium
Normal lab values of 1.8 - 3.0 mEq/L

Hypomagnesemia
Symptoms are behavioral changes, irritability, increased reflexes, cramps, tetany, tachycardia, hypotension
Hypermagnesemia
Skeletal smooth muscle contraction, weakness, excess nerve function, hypotension, bradycardia, respiratory distress, and loss of DTR

Normal body pH

7.35-7.45
Normal range for pCO2
35-45mmHg

Normal range for pO2
80-100mmHg
Normal O2 saturation
95 - 100%
Normal HCO3- levels
22-26 mEq/L