Breast Cancer: Knocking Out A Killer

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BRCA1 can be found in the breast tissue. It is normally used to help regulate the cell cycle so the cell can restore DNA that has been damaged. The gene also prevents the cell from reproducing to fast. When BRCA1 has been mutated, it produces an unreliable protein that predisposes the breast to cancer. Even though not everyone with BRCA1 or BRCA2 form cancer , people with these gene mutations should seek the best preventative treatments to eliminate their high risk of breast cancer because there is a distinct connection to people with this mutation that have also contracted cancer. Just one inherited, mutated gene greatly increases the risk of cancer. In the first article, Breast Cancer: Knocking out a Killer, it discusses the key factors of the breast cancer genes, BRCA1 and BRCA2. These genes are responsible for 30 to 80 percent of all hereditary forms of the disease. Although, the absence of the BRCA1 protein does not directly cause cancer, it does make cells more susceptible to mutations that in turn can lead to malignant transformations. (Pistoi, 2001) Further more, scientist realized that in order to recreate a more exact example of the studies in the growth of cancer, they needed to use living models. They used mice to carry out these …show more content…
Some of their common factors are that they both deal with the investigation on research regarding the deadly gene mutation, BRCA1. Both studies continued searching for more options for the effected women. Throughout their trials, the scientist also used mice as their living models. Some of the differences in these articles are that one deals with a specific drug along with the further research on that drug. Unlike the other article, that mostly explained the factors of the mutative gene and the hopes to find more research. One of the reasons for this difference would be the time frame in which these studies were

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