Tranrectal ultrasound (TRUS) guided biopsy involves acquiring a small tissue specimen from the prostate gland for evaluation by a pathologist using the Gleason Scoring System. A Gleason score ranging from 1 to 5 is allocated by a pathologist based on the grade of each of the two most common tumor patterns, i.e. architectural and neoplasm patterns. A score of 5 for the architectural pattern signifies that the tissue is the least differentiated typical of cancerous tissue; whereas a neoplasm score of 5 denotes that the tumor looks like the most dominant neoplasm pattern. These two scores are summed together to decide the riskiness of the neoplasm where a score between 6 and 10 means the tumor is cancerous [11]. Although biopsy is the most precise
