The Use Of Laboratory Animals Of Shanghai Slac Essay
1658 Words Sep 3rd, 2016 null Page
2.2 Ethics considerations
Animal study was carried out strictly in accordance with the Guidelines for the Care and Use of Laboratory Animals of Shanghai Jiao Tong University. The protocol was approved by Shanghai Municipal Laboratory Animal Management Office, Shanghai Municipal Science and Technology Commission (Permit Number: 11ZR1416200).
2.3 Construction of vitamin B6 deficient mouse model
In order to investigate the influence of vitamin B6 deficiency on the immune system and the subsequent remediation by vitamin B6 supplementation, three-week-old BALBc mice, weighing an average of 10 g, were randomly divided into 4 dietary groups, namely the control group (+VB6+), the deficiency group (-VB6-), the recovery group (-VB6+), and the excess group (-VB6++). Each group contained 7 mice. They were housed in the standard…