The Effect Of Microbiota On Human Health Through A Commensal Interaction

1153 Words Nov 16th, 2015 null Page
Microbiota are microscopic organisms such as viruses, bacteria, archaea, and eukaryotes that influence human health through a commensal interaction. Location of microbiota can be internal or external such as the gut, mouth, placenta, skin, and vagina. These microbes are classified into four major phyla: Firmicutes, Bacteriodetes, Actinobacteria, and Proteobacteria. Microorganisms in the Firmicute phylum are typically Gram positive bacteria, either rod-shaped or spherical and function as obligate or facultative anaerobes. Firmicutes are predominately found in the vagina. Microorganisms under the phylum Bacteriodetes are typically Gram negative bacteria and are strictly anaerobes. These are mainly found in the gut microbiome including 100 trillion others not mentioned here! Microorganisms in the Actinobacteria phylum are non-motile, anaerobic Gram positive bacteria that are able to form branching rods that radiate outwards. Actinobacteria are most commonly located on the skin. Finally, Proteobacteria are also Gram negative and can either be aerobic or anaerobic and are mainly located in the placenta (4). Some of the technology used to identify the different microbiota include DNA microarrays, quantitative PCR, fluorescence in situ hybridization (FISH), denaturing gradient gel electrophoresis (DGGE), and terminal restriction fragment length polymorphism (T-RFLP). A key feature of all these techniques is that they utilize sequence divergences of the 16S rRNA known as the small…

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