Symptoms And Treatment Of Chronic Kidney Disease Mineral Bone Disorder

1562 Words Feb 29th, 2016 null Page
CKD-MBD
Chronic kidney disease can reck havoc on the bones. When the kidneys fail to regulate the balance of phosphorus, calcium, and vitamin D or when hypooclaemia dn hyperphopahtemia persist, parathyroid hormone will increase to compensate. Although the body is adaptable it will eventually fall behind. According to Ruf & Clifford (2010), "The cornerstone of management of chronic kidney disease-mineral bone disorder is to maintain normal bone turnover by maintaining adequate PTH and vitamin D receptor agonism" (p. 99). Ruf & Clifford (2010) explain how management of CKD-MBD is distinctly different from the regular treatment of osteoporosis (p. 99). The first step of treatment is finding the right drug regimen for the individual. The Primary care provider will educate the individual on their options, why they are taking each drug and possible side effects. One of the first drugs is a phosphate binder. "Phosphorus binders reduce levels of circulating phosphorus and subsequently decrease PTH levels" (Ruf & Clifford, 2010, p. 99). Vitamin D regulates bone turnover. It will increase intestinal absorption of calcium and phosphorus. A Calcimimetic may be given to reduce PTH secretion and thus lower calcium and phosphorus levels (Ruf & Clifford, 2010, p. 100). The last category of drug is a bisphosphonate. "Bisphosphonates inhibit osteoclast activity and decades the rate of bone resorption prevailing in osteoporosis" (Ruf & Clifford, 2010, p. 100). They reserved for…

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