Symptoms And Treatment Of Alzheimer 's Disease Essay example

896 Words Dec 24th, 2016 4 Pages
Cancer is one of the most life-threatening diseases requiring a lot of development in cures and preventative therapies. A wide variety of anticancer drugs including those that directly or indirectly act on the cells causing cell death have been developed,. Nowadays, natural products have received increasing attention for their potential as novel cancer preventive and therapeutic agents [1,2].
Alzheimer’s disease (AD) is one of the most common causes of mental deterioration in elderly people. It is a progressive degenerative neurological disorder resulting in impaired memory and behavior. Several studies proposed that the degeneration of cholinergic neurons in the basal forebrain and the associated loss cholinergic neurotransmission in the cerebral cortex and other significantly deteriorated the cognitive function as obsereved in the patients with AD [3]. One of the most promising approaches for treating this disease is to enhance the acetylcholine level in the brain using acetylcholinesterase (AChE) inhibitor [4].
The genus Phlomis, perennial herbs of the Lamiaceae family, consists of more than 100 species distributed throughout Asia, Africa, and Europe [5]. Phlomis umbrosa is distributed in several countries of the Southeast Asia. The root of P. umbrosa has been traditionally used for the treatment of hemorrhage, bronchitis, cold, and bone fractures [6]. Previous phytochemical investigations of the genus Phlomis have shown that they contain phenolics, iridoids, flavonoids,…

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