Rhabdomyolysis causes the myosin and actin to degenerate into smaller proteins, and he body reacts by increasing swelling to the injured tissue, in this case the legs, to send repair cells to the area. Myoglobin can now be releases from the tissue. Unfortunately, it leaves the tissue and enters the bloodstream where it travels to the kidneys. Also, when myoglobin is released, intracellular potassium, sodium, and chloride find their way into the circulatory system which results in an irregular heartbeat, another symptom of rhabdomyolysis. (Jordan, K. S., & Mannle, S. E.
