Introduction
By definition Rhabdomylosis is a rare disease that causes a breakdown of muscle tissue that releases a damaging protein into the blood. Fewer than 200,000 people are diagnosed in the United States yearly. Rhabdomylosis causes an excess level of myoglobin, which can and eventually will cause further injury. There are multiple causes of this disease such as trauma, nontraumatic exertional rhabdomyolysis, and other miscellaneous causes. Risk factors range from seizures to alcoholism and early treatment is crucial to reduce the risk of kidney damage. Patients will feel pain, fatigue, have abnormal urine color and body aches. This disease is diagnosed through urine and blood tests looking for signs of muscle damage. Initial management …show more content…
Muscle compression or trauma is a common cause for the disease and seen primarily in car accidents and collapsed buildings. Children suffering from abuse, torture victims, and individuals unable to move due to coma, paralysis or individuals forced to lie in one position for hours either due to injury or surgery can see symptoms of rhabdomyolysis. Nontraumatic exertional rhabdomyolysis occurs when normal muscles lack the energy supply to meet demands. Rhabdomyolysis may arise if a person is physically untrained, exhaustion from heat, and hypokalemia caused by potassium loss from sweating. Nonexertional and nontraumatic causes include “drugs, toxins, infection, electrolyte abnormalities, endocrinopathies, and inflammatory myopathies.” Prescribed medications, drugs of abuse and alcohol can cause rhabdomyolysis through several different mechanisms. Overdoses, alcohol induced coma and CNS depressants can lead to immobilization and ischemic compression of muscle. Drug induced agitation like seizures will contribute to the excess muscle energy demands. Toxins other than medications can cause rhabdomyolysis for example: snake venom, mushrooms and certain fish (for example Haff
By definition Rhabdomylosis is a rare disease that causes a breakdown of muscle tissue that releases a damaging protein into the blood. Fewer than 200,000 people are diagnosed in the United States yearly. Rhabdomylosis causes an excess level of myoglobin, which can and eventually will cause further injury. There are multiple causes of this disease such as trauma, nontraumatic exertional rhabdomyolysis, and other miscellaneous causes. Risk factors range from seizures to alcoholism and early treatment is crucial to reduce the risk of kidney damage. Patients will feel pain, fatigue, have abnormal urine color and body aches. This disease is diagnosed through urine and blood tests looking for signs of muscle damage. Initial management …show more content…
Muscle compression or trauma is a common cause for the disease and seen primarily in car accidents and collapsed buildings. Children suffering from abuse, torture victims, and individuals unable to move due to coma, paralysis or individuals forced to lie in one position for hours either due to injury or surgery can see symptoms of rhabdomyolysis. Nontraumatic exertional rhabdomyolysis occurs when normal muscles lack the energy supply to meet demands. Rhabdomyolysis may arise if a person is physically untrained, exhaustion from heat, and hypokalemia caused by potassium loss from sweating. Nonexertional and nontraumatic causes include “drugs, toxins, infection, electrolyte abnormalities, endocrinopathies, and inflammatory myopathies.” Prescribed medications, drugs of abuse and alcohol can cause rhabdomyolysis through several different mechanisms. Overdoses, alcohol induced coma and CNS depressants can lead to immobilization and ischemic compression of muscle. Drug induced agitation like seizures will contribute to the excess muscle energy demands. Toxins other than medications can cause rhabdomyolysis for example: snake venom, mushrooms and certain fish (for example Haff