Relative Effectiveness Of Penicillin, Neomycin And Erythromycin On The Inhibition Of Growth Of Streptococcus Pneumoniae

1659 Words 7 Pages
Sydney Meyers
Relative effectiveness of penicillin, neomycin and erythromycin on the inhibition of growth of Streptococcus pneumoniae
Introduction:
An approximate 1.1 million annual deaths worldwide are attributed to the to bacteria known as Streptococcus pneumoniae. Today, S. pneumoniae is among the most significant causes of bacterial disease in humans and remains to be one of the top 10 causes of death in the U.S (Hoskins, 2001). This pathogenic bacteria causes a variety of clinical issues and is the leading cause of meningitis and bacterial pneumonia in the United States (Hoskins, 2001). This bacteria has also been found to be a major cause of ear/sinus infections, bloodstream infections and even sepsis. (Hoskins, 2001). Researchers estimate that S. pneumoniae is responsible for over 3000 cases of meningitis, 500,000 cases of pneumonia and kills upwards of 40,000 persons in this country annually (Abrutyn & Fuchs, 2000).
S. pneumoniae is a gram-positive coccus bacterial pathogen that grows in pairs and chains and colonizes the human upper respiratory tract (Abrutyn & Fuchs, 2000). This bacteria belongs to the Firmicutes phylum and has the ability to invade host cells and cause many life-threatening infections such as meningitis, bacteremia and sepsis (Hoskins, 2001). S. pneumoniae is an alpha-hemolytic bacteria and has the ability to oxidize hemoglobin (Abrutyn & Fuchs, 2000). The virulence factors in the cell wall of S. pneumoniae is what make it a very…

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