Momordica Chaaranti: The Adverse Effects Of Bitter Melon?

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1. Momordica charanti, also known as bitter melon, is a green colored vegetable/fruit that has a bumpy and rough surface to it. It is an unripe fruit that resembles a small cucumber and is used as a vegetable and tastes very bitter. People often use the roots, leaves, seeds, and the seeds oil as part of cooking purposes and often use it for medicinal purposes. Bitter melon is commonly found and used in Asia, South America, India, and East Africa.

2. Many people use bitter melon for multiple reasons such as treating, asthma, cancer, high blood pressure, viral infections such as HIV and AIDS, and GI disorders such as gastric ulcers. But overall, the primary use of bitter melon is in reducing blood glucose levels in type 2 diabetes. Bitter melon
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There are many side effects of bitter melon such as nausea, vomiting, abdominal pain, headache, and low blood sugar. The CNS adverse effects of bitter melon are coma, fever, and headache. The GI adverse effects are abdominal pain and diarrhea. The GU adverse effects are uterine bleeding and uterine contractions. There is also a hematologic adverse effect that leads to hemolytic anemia. The hepatic adverse effect is hepatotoxicity. The vicine, which is the seed inside the bitter melon, can cause toxicity if ingested. Bitter melon can also activate a hypersensitivity reaction in some people. Some drug interactions with the use of bitter melon any hypoglycemic drugs along with insulin, which can cause a rapid decrease in blood sugar levels when used simultaneously. It also has a known drug interaction with P-glycoprotein that increases the chance of toxicity. Lastly, any cytochrome P450 substrates are inhibited with the use of bitter melon extract because it interferes with the metabolism of the drug. The patients that should avoid bitter melon are pregnant women and children. In pregnant women, this herb can cause uterine bleeding and uterine contractions, which can lead to miscarriage. Children are to use this herb with caution because the red arlis around the bitter melon seeds has a toxic effect on them that can lead to death. Bitter melon is also contraindicated in people who already have low blood sugar levels (hypoglycemia) because this herb drops their blood sugar

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