A vaccine is a substance developed from minimal, and weak amounts of the disease-causing agent used to increase the production of antibodies and provide immunity against the disease, without giving rise to the disease. Limited research has been conducted on active vaccinations against methamphetamine. The research that has been done has shown to have very little to no success in behavioral studies. Consequently, studies have been redirected to passive vaccination. Even though passive vaccination has shown efficacy in reduced METH-related behavior, the expense is high. Active vaccination, however, creates an immunological memory upon recurrent introduction of the conjugate drug. The key feature allows for longer protection, decrease in costs of treatment, and a possible way of preventing relapse (Moreno et al. 2011). The urgency for developing an effective approach to a vaccine against methamphetamine addiction is therefore imperative.
According to the National Institute for Drug Addiction (NIDA), a successful anti-drug vaccination is one …show more content…
Out of six potential vaccines, three of them were showed promising results by causing a strong antibody response to meth. Janda and his lab performed two experiments, one of which was to screen the three promising vaccines from their earlier experiment, and the other experiment was to utilize the MH6 vaccine to determine its effects on meth-induced hypothermia with rats (Miller, et al. 2013). In summary, the study found that active vaccination diminished the METH-induced physiological, and behavioral effects. Additionally, the distribution of METH to the brain was lowered due to the accumulation of antibodies in the peripheral brain, which further confirms the efficacy of the MH6 vaccine (Miller,
According to the National Institute for Drug Addiction (NIDA), a successful anti-drug vaccination is one …show more content…
Out of six potential vaccines, three of them were showed promising results by causing a strong antibody response to meth. Janda and his lab performed two experiments, one of which was to screen the three promising vaccines from their earlier experiment, and the other experiment was to utilize the MH6 vaccine to determine its effects on meth-induced hypothermia with rats (Miller, et al. 2013). In summary, the study found that active vaccination diminished the METH-induced physiological, and behavioral effects. Additionally, the distribution of METH to the brain was lowered due to the accumulation of antibodies in the peripheral brain, which further confirms the efficacy of the MH6 vaccine (Miller,