Importance Of Precision Medicine 's Success Essay
During the State of the Union, President Obama said, “one size does not fit all when it comes to disease”; this statement could not be more accurate (Secretary, 2015a, p. 1). By identifying what makes each patient unique through genomic variation, physicians could identify mutations that make a patient more susceptible to disease, allowing physicians to help prevent the mutation in question from harming the patient (Leonard, 2015). Pinpointing efficacy could also help identify the most valuable treatment for the particular condition.
As medical technology and clinical research have progressed, it has been found that a majority of disease states are largely genetically based (Wright, 2014, p. 2). Seemingly minute abnormalities in the genome can be devastating to the health of the individual. By focusing on the genome, the cause of disease and the subsequent effect of treatment can be clarified. Presently, researchers are focusing on the cancer-immunity cycle—the identification of cancer cells by the immune system and the subsequent effector immune response, sent to kill the tumor cells (Kaufman MD, 2014).
The immune system plays a substantial role in cancer. Cells transformed by either oncogenic viruses or point mutations develop genetically distinct characteristics. The adaptive immune response involves the patient’s immune system responding to tumor-specific antigens.
Current cancer treatments are moving towards…