Essay about Iga Nephropathy And Berger 's Disease

1315 Words Jul 29th, 2016 6 Pages
IgA nephropathy or Berger’s Disease, is a kidney disorder that arises when IgA settles in the kidneys. More specifically, when the IgA protein accumulates or clumps in the small blood vessels of the kidney, triggering inflammation which damages the glomeruli tissue (Mayo Clinic). Your kidneys are two bean-shaped organs located on the posterior abdominal wall. One of the kidneys main functions is to filter toxic waste from the blood; the glomeruli play an important role in this process. The more IgA that damages the glomeruli, the more it forces the kidneys to lose its ability to clear waste.

IgA is an immunoglobulin or antibody developed by the immune system that helps fight infections within our body. It is produced in the mucous, saliva, tears, and breastmilk and found in areas exposed to the environment. IgA neutralizes foreign substances such as bacteria or viruses mainly in the respiratory and gastrointestinal tract to prevent them from infecting epithelial tissue (McKinley).
IgA nephropathy is generally termed silent because symptoms potentially don’t start occurring for years. The first sign of IgA nephropathy in many people is blood in the urine, which is caused from the damaged glomeruli. The blood is most likely to appear during a cold or other infection. As the blood increases it may turn the urine pink or similar to the color of cola. However, only doctors or nurses can detect and diagnose when blood is present in the urine by performing a urinalysis…

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