Hepatitis B And Its Effect On The Liver Essay

1187 Words Mar 14th, 2015 null Page
The Microbe
Hepatitis B virus belongs to a group called, Hepadnaviridae which consists of diseases that contain deoxyribonucleic acid (DNA) and affect the liver. Hepatitis B is a virus therefore; hepatitis B requires a living host to replicate viral particles. Hepatitis B consists of a nucleic acid core, a protein coat, and a lipid envelope. The hepatitis B virus contains a partially double-stranded DNA within the nucleic acid core because one of the full-length strands is linked to the viral DNA polymerase. The lipid envelope that surrounds the capsid contains glycoprotein spikes which are used to attach to receptors found on the host cell. Once the virus enters the body, it is adsorbed to the host cell via the glycoprotein spikes. The virus then penetrates into the host cell by fusing into the host cell membrane. The virus’ nucleic acid is uncoated inside the host cell resulting in, a release of the viral DNA. The viral DNA is expressed to generate more viral DNA and proteins. The viral proteins and DNA, assemble to create new viruses within the host cell. The new viruses bud out of the host cell and continue to infect other host cells within the body. The hepatitis B virus can only replicate in, “humans and chimpanzees” (Kenyon College Microbe Wiki, 2010). Hepatitis B virus is, “highly polymorphic, ranging from inapparent forms to acute hepatitis and severe chronic liver disease.” (Tiollais, Pourcel, & Dejean, 1985). Acute hepatitis lasts less than six months,…

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