Evaluation Of The Physiologic Effects Of High-Flow Nasal Cannula Case Study

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Evaluation of the physiologic effects of high-flow nasal cannula (HFNC), which “is a heated, humidified, high-flow oxygen delivery system that can generate total gas flows of up to 60 L/min with an adjustable FIO2”, compared to conventional oxygen therapy (COT) for patients with hypoxemia and acute dyspnea in the emergency department was the focus of this study published in the American Association for Respiratory Care Journal (Rittayami, Tscheikuna, Praphruetkit, & Kijpinyochai, 2015). The study had two goals: (1) to evaluate the level of dyspnea after use of HFNC (2) to evaluate patient’s comfort, change in breathing rate, adverse effects, and frequency of hospitalization (Rittayami et al., 2015).
Forty randomized subjects participated in
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The positive effects of HFNC were seen as early as 5 minutes after intervention through the end of the study, except at 30minutes where there seemed to be no change (Rittayami et al., 2015). The comfort level of the subjects who used the HFNC was reported to be higher than that of the subjects who used COT (Rittayami et al., 2015). During the 10 minute to 30 minute period, a substantial reduction of breathing frequency was found in the HFNC subjects (Rittayami et al., 2015). The heart rate was

also notably lower in the HFNC group at the end of the study (Rittayami et al., 2015). There were no severe adverse effects at the end of the study (Rittayami et al., 2015). In the HFNC group, there were a slight reduction in hospitalization (Rittayami et al., 2015).
Overall, the study demonstrated that HFNC was better tolerated and more comfortable for the subjects than the use of COT. It showed an immediate improvement in the level of dyspnea, and a reduction of breathing frequency throughout the intervention period. The study also demonstrated a downward trend of hospitalization with the use of HFNC. In conclusion to the study, HFNC may be a benefit to patients in the emergency department who require oxygen therapy (Rittayami et al.,
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It was interesting to understand the effects of HFNC on acute dyspnea patients and the significant improvement it can have. The study explained the mechanics of the HFNC, which was clear and easy to understand. The study highlighted the importance of using HFNC to support the high inspiratory flows a patient with acute dyspnea and hypoxemia may need to decrease their work of breathing. The study flowed well, and the details were presented clearly and were easy to comprehend. The study was not overtaken by figures, calculations, and graphs that were too complicated to understand. The authors explained that this study was the first randomized study on patients treated in the emergency department with acute dyspnea and hypoxemia. They did mention that several other studies have been conducted in patients with acute respiratory failure, which has consistent results. I believe that another study with a greater number of participants may be needed to confirm satisfactory

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