Clostridium Difficile Research Paper
difficile can be colitis, which causes the colon to be inflamed, cause diarrhea, fever and abdominal cramps. The discovery of C. difficile was John Bartlett, he began trials investigating the problem of antibiotic-associated diarrhea and pseudomembranous (a layer which resembles a membrane, especially one forming over a mucosal surface) the discovery of Clostridium difficile and he identified it as the leading cause of hospital-associated infections.
The prognosis for C. difficile is being able to recover even without treatment and if not it is perforation (rupture) of the colon and death. If you have had C. difficile infection before, you have a one in four chance of the infection returning, so it is important to get treated right away properly by your physician.
I have looked up on an article that there is current research on the bacterium C. difficile. There is a couple antibiotics that NIAID (National Institute of Allergy and Infectious Diseases) is currently supporting. First, there is “CRS3123” which inhibits an enzyme required by C. difficile to make proteins and then there is “Amixicile” which targets an enzyme found in anaerobic bacteria, like in C. difficile. The NIAID is supporting research that focuses on understanding basic mechanisms of C. difficile spore-formation and spore germination and also the spread within health care facilities. The major difference between C. difficile is that usually you contract it from antibiotic use. It is really tough to tell the difference from C. difficile to other digestive system infections because they usually have all the same symptoms, but C. difficile is more common in hospitals and health care