Causes And Effect Of Ergot Poisoning Essay

1181 Words Nov 22nd, 2016 5 Pages
Due to its miniscule size and the fact Claviceps purpurea is an unknown to these people, many commoners that consumed the bakery products made from the flour that was recently made became very ill and fell into the hands of Ergot of rye poisoning, a disease given the nickname back then “holy fire" or "St. Anthony’s fire (Schumann 2016). While ergot poisoning is no longer a concern to us due to the cleansing process harvested grain must undergo through to remove any such parasites or anything that could have been on the agriculture, the uses of ergot fungi began to be realized and thus, medicine/drug to precipitate childbirth was the first product created from this parasite. However, this discovery was not beneficial in the later years once the side effects of uterine spasms and dangers to the child started to be noticed and taken in according, but this negative outbreak quickly became irrelevant once W. A. Jacobs and L.C. Craig of the Rockefeller Institute of New York succeeded in isolating and characterizing the nucleus common to all ergot alkaloids, later naming it “lysergic acid” (May 1998). Albert Hoffman took it one step further in the late 1930s’, experimenting on lysergic acid with other reagents to create numerous amounts of derivatives (solutions); one of these derivatives was diethylamide, made by the addition of the -N(C2H5)2 group, forming lysergic acid diethylamide or otherwise known as “LSD-” (May 1998). LSD does acquire a decent amount of history behind it,…

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