Joseline Jacamo
To the Bitter End: A Case Examining the Genetics of PTC Sensitivity
First part : Questions
1. What L.H Snyder is inferred by using “Mendelian marker” is to convey that all Mendelian traits which is inherited from the parent and pass down to its offspring can be utilized as a maker.
2. Some question that Dr. Snyder could ask is “How would you know if PTC is an inherited trait?. In addition, “How are you going to test if PTC is an inherited trait or not?. Also, if “PTC tasting is inherited would it be considered a Mendelian Maker or not?”.
3. His hypothesis would be, If the ability to taste PTC is inherited, …show more content…
When both parents are taster and their children not that means that the parent has alleles that are heterozygous dominant therefore their children possess the capability of not being a taster of PTC.
4. The consequence of having a parent that cannot taste the PTC will result if having children that can taste the PTC means that the PTC has to be a dominant trait in at least one parent to be able to be a taster of PTC in their children.
5. With the provided data, I can conclude that people that are non-taster of PTC is a homozygous recessive trait. Since the results, supports that when neither parent can taste their offspring cannot taste PTC as well. As a result, the offspring can also be taste blind to PTC.
6. When doing a testcross the outcomes are the parents can taste the TTtt Tttt and the ratio zero: four: zero and zero: two :two. The genotype that one parent can taste ptc and the can’t is TTtt / Tttt and can’t taste is tt tt. The outcome zero: four: zero characterizes when a homozygous recessive and homozygous dominant when they are pair. As a result, the offspring will exclusively be heterozygous dominant. The other ratio and zero: two :two it characterizes the when homozygous recessive and the dominant are crossed. As a result, there will not be any homozygous dominant.
Third …show more content…
A collection of genes that share the same significant features is a family gene. For example, close relative such as brothers and sister share similar sequences of DNA.
2. SNPs ( Single nucleotide Polymorphism) is the greatest mutual form of genetic variation between humans (Thieman,2013). As a result, it makes up to ninety percent of human genetic variation and if SNPs happens in a gene sequence, it can cause a change in protein structure which can be detrimental. Moreover, a haplotype is referred as a combination of alleles or a set of SNPS that can be found in the same chromosome.
3. If PAV which codes for proline, alanine and valine is the original, therefore the AVI which codes for alanine, valine, and isoleucine is the missense codon (Overath, 2011). As a result, when there is an alteration in which a only one nucleotide changes to a different amino acid it’s a missense mutation. The “functional enzyme hypothesis” is the idea that every a gene codes for a only one enzyme and that as a result alters a stage in the metabolic pathway. Therefore, if there is any type of mutation happens, it will affect the enzyme that is made and the metabolic pathway.
4.
5. The ones that can taste PTC has a phenotype of PAV/AVI or PAV/PAV, and the ones that cannot taste the PTC have a phenotype of
To the Bitter End: A Case Examining the Genetics of PTC Sensitivity
First part : Questions
1. What L.H Snyder is inferred by using “Mendelian marker” is to convey that all Mendelian traits which is inherited from the parent and pass down to its offspring can be utilized as a maker.
2. Some question that Dr. Snyder could ask is “How would you know if PTC is an inherited trait?. In addition, “How are you going to test if PTC is an inherited trait or not?. Also, if “PTC tasting is inherited would it be considered a Mendelian Maker or not?”.
3. His hypothesis would be, If the ability to taste PTC is inherited, …show more content…
When both parents are taster and their children not that means that the parent has alleles that are heterozygous dominant therefore their children possess the capability of not being a taster of PTC.
4. The consequence of having a parent that cannot taste the PTC will result if having children that can taste the PTC means that the PTC has to be a dominant trait in at least one parent to be able to be a taster of PTC in their children.
5. With the provided data, I can conclude that people that are non-taster of PTC is a homozygous recessive trait. Since the results, supports that when neither parent can taste their offspring cannot taste PTC as well. As a result, the offspring can also be taste blind to PTC.
6. When doing a testcross the outcomes are the parents can taste the TTtt Tttt and the ratio zero: four: zero and zero: two :two. The genotype that one parent can taste ptc and the can’t is TTtt / Tttt and can’t taste is tt tt. The outcome zero: four: zero characterizes when a homozygous recessive and homozygous dominant when they are pair. As a result, the offspring will exclusively be heterozygous dominant. The other ratio and zero: two :two it characterizes the when homozygous recessive and the dominant are crossed. As a result, there will not be any homozygous dominant.
Third …show more content…
A collection of genes that share the same significant features is a family gene. For example, close relative such as brothers and sister share similar sequences of DNA.
2. SNPs ( Single nucleotide Polymorphism) is the greatest mutual form of genetic variation between humans (Thieman,2013). As a result, it makes up to ninety percent of human genetic variation and if SNPs happens in a gene sequence, it can cause a change in protein structure which can be detrimental. Moreover, a haplotype is referred as a combination of alleles or a set of SNPS that can be found in the same chromosome.
3. If PAV which codes for proline, alanine and valine is the original, therefore the AVI which codes for alanine, valine, and isoleucine is the missense codon (Overath, 2011). As a result, when there is an alteration in which a only one nucleotide changes to a different amino acid it’s a missense mutation. The “functional enzyme hypothesis” is the idea that every a gene codes for a only one enzyme and that as a result alters a stage in the metabolic pathway. Therefore, if there is any type of mutation happens, it will affect the enzyme that is made and the metabolic pathway.
4.
5. The ones that can taste PTC has a phenotype of PAV/AVI or PAV/PAV, and the ones that cannot taste the PTC have a phenotype of