Antiemetics Research Paper

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Antiemetics

Overview:
Antiemetics are used for nausea and to prevent vomiting and also used for motion sickness. These drugs can be bought over the counter. (OTC)
Action:
Dimenhydrenate or Dramamine is an antihistamine. It should be taken one hour before travelling, and will prevent motion sickness. The antihistamine is available in children’s liquid formula and in a Less Drowsy Formula that may have fewer sedative side effects.
Meclizine hydrochloride (Bonine) treats vomiting and dizziness and do not operate machinery while taking this medication. This is available over the counter.

Anticholinergics

Hyoscine hydrobromide may be prescribed as a skin patch to relieve motion sickness and it is also available over the counter as tablets. Side effects may include dry mouth, drowsiness, difficulty
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It takes 15-20 to take effect and lasts for 4-8 hours. Salicylates cross the blood brain barrier. It is metabolized in the liver and excreted in the urine.
Side Effects
Hypersensitivity to aspirin type drugs are to an accumulation of prostaglandins, after pathways break down prostaglandins are blocked. Inhibition of prostaglandin synthesis may result in some serious side effects like peptic ulcers, and problems with blood clotting. Liver damage sometimes occurs with aspirin and renal or kidney toxicity with NSAIDs. Aspirin is also the cause of Rye Syndrome, a degenerative disease of the brain and fatty tissue of the liver.
Contraindications of acetylsalicylic acid aspirin (ASA)
People who are allergic to aspirin or NSAIDS should not take it. Taking low dose 81mg daily aspirin should not be taken by healthy people to prevent a first heart event or stroke. There is an increased risk of bleeding in the stomach, intestines and in the brain. So do not take it if you have a serious allergy or a history of

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