Vertigo Research Paper

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Central nervous system disease that cause vertigo include disease of the brainstem. vascular nervous system causes malformations, tumor of the brainstem and cerebellum ,multiple sclerosis, , vertebrobasilar migraine.
Vertigo of central origin often becomes disabling. The associated nystagmus is often non fatigable, the orientation of this type of vertigo is vertical rather than horizontal, without latency, and unsuppressed by visual fixation. ENG is useful in documenting these characteristics. There are commonly other signs of brainstem dysfunction (eg, cranial nerve palsies; motor, sensory, or cerebellar deficits in the limbs or of increased intracranial pressure. Auditory function is generally spared. The underlying cause should be treated.(9)
1. Vestibular Epilepsy: It is a rare cortical vertigo syndrome
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Vertigo lasting more than a few days is suggestive of permanent vestibular injury (e.g., stroke), and medications should be stopped to allow the brain to adapt to new vestibular input.
A wide variety of medications are used to treat vertigo and the frequently concurrent nausea and emesis. These medications exhibit various combinations of acetylcholine, dopamine, and histamine receptor antagonism. The American Gastroenterological Association recommends anticholinergics and antihistamines for the treatment of nausea associated with vertigo or motion sickness (22). Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter in the vestibular system. Benzodiazepines enhance the action of GABA in the central nervous system (CNS) and are effective in relieving vertigo and anxiety. Older patients are at particular risk for side effects of vestibular suppressant medications (e.g.,

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