Alzheimer Disease (AD) occurs when fibrous proteins accumulate in the brain causing neural dysfunction (Pulawski et al. 2012). Scientists have identified some key characteristics known as Risk Genes, used in this study, to measure the influence of these Genes on clinical and pathological measures of AD (Karch et al. 2012). 112 Parietal lobes of deceased European American were divided into a control (39) and case group (73). The percentage of males in treatment was 42% and in control 44%. Finally the mean age for treatment was 87±7 and for control was 86±9. Then, RNA was extracted, processed and recorded to create a database of AD (Karch et al. 2012). Finally, the study was replicated. Results showed that genes such as ABCA7 are associated with high levels of CDR (Clinical Dementia Rating) and genes related in function, might be related in RNA composition (Karch et al. 2012).
Although this research did not violate any ethical guidelines to the participants, the outcomes might be compromised due to a problematic procedure. First, we will analyze sample and structure and then consent to participate. …show more content…
Also, there are more participants in the treatment (73) than in the control group (39) and the age range varies too. Because this study is not focusing on AD in women but in general, distribution should had included an equal number of females and males. Furthermore, when replicated, the proportion of participants changed. However, the conclusion was the same. According to past literature, there is a higher prevalence of AD in women (14.2%) compared to men (8.8%) both aged 85-89 years old (Schmidt et al. 2008), which might suggest a reason for the sample distribution. As a consequent the results obtained by the study can be
Although this research did not violate any ethical guidelines to the participants, the outcomes might be compromised due to a problematic procedure. First, we will analyze sample and structure and then consent to participate. …show more content…
Also, there are more participants in the treatment (73) than in the control group (39) and the age range varies too. Because this study is not focusing on AD in women but in general, distribution should had included an equal number of females and males. Furthermore, when replicated, the proportion of participants changed. However, the conclusion was the same. According to past literature, there is a higher prevalence of AD in women (14.2%) compared to men (8.8%) both aged 85-89 years old (Schmidt et al. 2008), which might suggest a reason for the sample distribution. As a consequent the results obtained by the study can be