Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
80 Cards in this Set
- Front
- Back
processes of urine formation |
filtration, reabsorption, secretion |
|
What are the most important nitrogenous wastes found in the blood? |
urea, uric acid, creatinine |
|
urea |
formed by the liver as an end product of protein breakdown when amino acids are used to produce energy |
|
uric acid |
released when nucleic acids are metabolized |
|
creatinine |
metabolism in muscle tissue |
|
Glomerular filtration |
nonselective, passive process in which fluid passes from the blood into the glomerular capsule part of the renal tube |
|
filtrate |
fluid in the capsule part of filtration |
|
tubular reabsorption |
begins as soon as the filtrate enters the proximal convoluted tubule. |
|
tubule cells |
"transporters" taking up needed substances from the filtrate and then passing them out their posterior aspect into the extracellular space |
|
tubular secretion |
essentially tubular reabsorption in reverse |
|
What is the kidney's role in fluid and electrolyte balance? |
volume and composition of bodily fluids |
|
aldosterone |
hormone that helps to regulate blood composition and blood volume by acting on the kidney |
|
Major factor regulating _______ ion content of the ECF and in the process helps regulate the concentration of other ions __+ and ____+ as well. |
sodium, K, Mg2 |
|
antidiuretic hormone |
Released when nerve impulses are sent to the posterior pituitary. This hormone prevents excessive water loss in the urine. |
|
ADH |
antidiuretic hormone |
|
_____ travels in the blood to its main target, the kidney's collecting ducts, where it causes the duct cells to reabsorb more water. |
ADH |
|
renin-angiotensin mechanism |
Most important trigger for aldosterone release, mediated by the juxtaglomerular apparatus, consists of a complex of modified smooth muscle cells in the afferent arteriole plus modified epithelial cells forming part of the distal convoluted tubule. |
|
Some things that might alter the color or urine. |
food, medication, stomach acidity, water intake |
|
specific gravity |
term used to compare how much heavier urine is than distilled water |
|
The specific gravity of pure water is __.__. |
1.0 |
|
The specific gravity of urine usually ranges from __.__ - __.__. |
1.001 - 1.035 |
|
Solutes normally present in urine. |
sodium and potassium ions, urea, uric acid, creatinine, ammonia, bicarbonate ions |
|
Glycosuria indicates abnormal levels of ________ in the urine. |
glucose |
|
Possible causes of Nonpathological Glycosuria |
excessive intake of sugary foods |
|
Possible causes of Pathological Glycosuria |
diabetes mellitus |
|
Proteinuria indicates abnormal levels of ________ in the urine. |
proteins |
|
Possible causes of Nonpathological Proteinuria |
physical exertion, pregnancy |
|
Possible causes of Pathological Proteinuria |
Glomerulonephritis, hypertension |
|
Pyuria indicates abnormal levels of ________ in the urine. |
Pus (WBCs and bacteria) |
|
Possible causes of Pyuria |
Urinary tract infection |
|
Hematuria indicates abnormal levels of ________ in the urine. |
RBCs |
|
Possible causes of Hematuria |
bleeding in the urinary tract (due to trauma, kidney stones, infection) |
|
Hemoglobinuria indicates abnormal levels of ________ in the urine. |
Hemoglobin |
|
Possible causes of Hemoglobin |
various: transfusion reaction, hemolytic anemia |
|
Bilirubinuria indicates abnormal levels of ________ in the urine. |
Bile pigment |
|
Possible causes of Bilirubinuria |
liver disease (hepatitis) |
|
renal calculi |
When urine becomes extremely concentrated, solutes such as uric acid salts form crystals that precipitate in the renal pelvis. |
|
>____ml is the maximum volume of urine a bladder can hold. |
1000 |
|
The female urethra is about ____inches long. |
1 1/2 |
|
What is the disadvantage of a short urethra? |
easy for bacteria to get to |
|
hypospadias |
found in male babies only, occurs when urethral orifice is located on the ventral surface of the penis |
|
What is the average adult daily urine output? (L) |
1.0-1.8 |
|
Babies and toddlers don't have control over their micturition because they have not yet gained control over their ___________ ____________. |
voluntary sphincter |
|
Significant dilation of the ______ calyces, _________ and __________ is one of the structural changes found in the urinary system of a pregnant woman's body. |
renal, pelvis, ureters |
|
During pregnancy, a woman's ureters _________ and become more tortuous. |
elongate |
|
The ureters may contain as much as _____ mL of urine by the third trimester. |
300 |
|
As pregnancy progresses, the ________ are compressed at the ________ brim by the _______ arteries, enlarging _______ vein complexes, and the growing _______, leading to further marked dilation and urinary _______. |
ureters, pelvic, iliac, ovarian, uterus, stasis |
|
A primipara's abdominal wall can be firmer than a woman with previous pregnancies which may increase the __________ and ________ on the ureters. |
resistance, pressure |
|
In most women, the _________ ureter is dilated to a greater extent than the ________. |
right, left |
|
Because of the effects of progresterone on smooth muscle, bladder tone __________. |
decreases |
|
The bladder mucosa becomes _________ with increased size and tortuosity of the blood vessels. |
hyperemic |
|
The mucosa becomes more edematous and vulnerable to _________ or _________ after engagement of the presenting part. |
trauma, infection |
|
The baseline intravesical pressure _______ due to the enlarged uterus. |
double |
|
How does urine output change in pregnancy? |
increases |
|
The bladder tone decreases as a result of the effects of progesterone on smooth muscle. What are the effects of this? |
increased risk of UTIs, urinary frequency and incontinence, alteration in accuracy of 24hr urine collections |
|
Urine output increases from a mean of ______ to _____mL per 24 hours primarily because of changes in sodium excretion. |
1475, 1919 |
|
Water and other substances appear in the urine in ________ quantities than were originally filtered due to reabsorption in the tubules. |
smaller |
|
Extracellular and intravascular volumes ______ during pregnancy. |
expand |
|
The accumulation of _________ in pregnancy is accompanied by accumulation of water. |
sodium |
|
Anatomic development of the ______ begins early in gestation of the fetus. |
kidneys |
|
Formation of the adult number of nephrons in a fetus by around ___ to ___ weeks. |
34, 36 |
|
Urine formation in the fetus begins by ___ to ___ wks. |
9, 10 |
|
Renal function does not reach levels comparable to adults until about ___ years of age. |
2 |
|
The kidneys arise from a ridge of _______ tissue that runs along the posterior wall of the abdominal cavity on either side of the primitive aorta. |
mesodermal |
|
The pronephros arises in the cervical region in the ______ week. |
third |
|
The pronephric ducts are incorporated into the __________ kidneys. |
mesonephric |
|
The mesonephros appears late in the _____ week forming forming a large, ovoid organ on either side of midline next to the developing gonads in the ________ and ________ regions. |
fourth, thoracic, lumbar |
|
The mesonephric ducts persists in the ______ as the wolffian duct and gives rise to the genital ducts. |
male |
|
The rest of the mesonephros regresses by ___ to ____ weeks as the metanephros begins to function. |
8, 10 |
|
The permanent kidneys arise during the ______ week from the ureteric bud at the caudal end of the mesonephric duct. |
fifth |
|
Formation of the permanent kidney involves ____ separate, interrelated processes. |
two |
|
The _____ bud grows out into the surrounding mesoderm, dilates and branches to form the urters, renal pelvis and collecting ducts. |
ureteric |
|
The first 9 branch generations by _____ weeks' gestational age and the remainder by 20 to 22 weeks. |
15 |
|
The growth of the ureteric bud into the surrounding mesoderm induces formation of small vesicles that elongate to form primitive _______ _________. |
renal tubules |
|
The proximal ends of the renal tubules form the _______ _______. |
Bowman capsule |
|
The ________ end comes into contact with the blind ends of the collecting ducts and fuses. |
distal |
|
Nephron formation begins at about ___ weeks in the juxtamedullary area and progresses toward the cortex. |
8 |
|
By ____ to ____ weeks, branching of the collecting ducts is complete and one third of the nephrons have been formed. |
20, 22 |
|
Nephrons continue to develop until ____ to ____ weeks, when adult numbers of nephrons are reached. |
34, 35 |
|
Initially the kidneys are in the ____ area. |
pelvic |