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311 Cards in this Set

  • Front
  • Back
opioids are __ or pain relieving medications
analgesic
studies have shown that properly managed medical use (taken exactly as prescribed) of opioid analgesics is __.
safe
__ and __ are used to alleviate severe pain, while __ is used for milder pain
Morphine, fentanyl, codeine
along with pain, opioids can be used to relieve ____
severe diarrhea and severe coughs
an opiate drug that is synthesized from morphine
heroin
opioids stimulate the opiate receptors __, __, and __ producing pleasure and pain relief.
delta, mu, and kappa
___ use of opioids can cause nerve cells to lose their ability to carry messages without presence of an opiate.
long term
opioids act on the __ system (controls emotions), the __ (controls coughing and breathing), and the __ (transmits pain signals).
limbic, brainstem, spinal cord
a pain relieving drug
analgesic
cough suppressing drug
antitussive
drug that stops diarrhea
antidiarreal
opioids can treat __ dependence
narcotic
opioids relieve all kinds of pain by __ the transmission of pain through the spinal cord or brain stem and alters the perception of pain in the pain center of the brain
blocking
kinds of pain opioids can block
visceral (internal organs of the body), somatic (skeletal muscles, bone, skin, teeth), the intense pain of cancer
in the past, narcotics were advertised as a cure for __
addiction to tobacco
refers to naturally occurring substances derived from the opium poppy (1600's) and their synthetic substitutes
narcotic
CNS depressants that produce insensibility or stupor, induce sleep, numbing, dull senses, relieves anxiety, dreamlike state, very dependancy producing
narcotics
give you the feeling of being wrapped in a warm cozy blanket on a cold morning
narcotics
the poppy (papaver somniferum) is known as the __
plant of joy or plant that brings sleep
the opium poppy has only __ days to manufacture opium
10
with the development of the __ and its use during the civil war, heroin addiction became more prevalent and more severe
hypodermic needle
1906-opium and its derivatives were found in ___ medicines; bought in local stores, and order through catalogs
50,000
in 1906 the rate of opiate use was ___ than today
higher proportionally
___ made narcotics illegal without a prescription
1914 Harrison Act
in 1980 a $10 bag of heroin was __ pure, by 2000 it was __ pure
<10%, 60-70%
heroin used during the Vietnam war was inexpensive and 95% pure; led to operation ____ where all soldiers were tested before being allowed to return to the US
golden flow
narcotics come to the US from:
Southeast Asia, Middle East, South America
the primary global producers of heroin
Afghanistan
the __ is the main source of of nonsynthetic narcotics
poppy
raw opium is changed by a __
heating process
milky substance from the opium plant is incised out of the __ and air-dried to form brown gummy substance
poppy capsule
___ references opium when the main character Dorothy falls asleep in the midst of a poppy field
The Wizard of Oz
opium came to the US in the mid-1800's when ___ came to build railroads and work in mines
chinese workers
morphine has been used in all wars since ___ to treat pain, dysentery, and fatigue
civil war
__-the hypodermic syringe boosted the abuse of opium
1853
individuals who use narcotics on a occasional or weekend basis
chippers
relapse
recidivism
eliminating drugs from the body (THE FIRST STEP in most treatments)
detoxification
condition caused by an allergic reaction to contaminants used to cut or dilute drugs
anaphylactic shock
drugs derived from opium
opioid
combining heroin and cocaine
speed balling
"women's tonic"
laudanum
injecting a drug of abuse intravenously
mainlining
these people:
-called chippers
-seldom use drug more than once a day
-can keep drugs around without using them
-avoid drugs when known addicts are present
-seldom, if ever binge
-know the source and dealer
-take fro recreation or relaxation
-do not take drug to escape from life's daily hassles
-do not use drugs to alleviate depression
controlled users
natural narcotics
derived from the opium poppy
modified natural narcotics
semisynthetic narcotics
synthetic narcotics
made in a lab
endogenous opioids
originate within the body
derived from the opium poppy, the pod is slit and allowed to ooze overnight, then scrapped. done since 3000 BC
opium
created in 1803 by Friedrich Serturner of Germany
-used for moderate to intense pain
-used medically
-the standard that other narcotics are measured by
-named after morpheus, the greek god of dream
morphine
created in 1832, low potency (12x<morphine), used to treat mild to moderate pain, atitussives, most widely used naturally occurring narcotic
Codeine
stimulant vs depressant, minor component of opium, converted into other compounds
theloaine
opium derivative used uas an antispasmodic
papaverine
created in 1832, low potency (12x<morphine), used to treat mild to moderate pain, atitussives, most widely used naturally occurring narcotic
Codeine
stimulant vs depressant, minor component of opium, converted into other compounds
theloaine
opium derivative used uas an antispasmodic
papaverine
opium __x <Morphine
10
heroin __x > Morphine
2-3
fentanyl __x > Morphine
1000-6000
semisynthetic narcotics are __ of the synthetic opioids
half
substances that have been derived indirectly from a natural narcotic
semisynthetic narcotic
derived from morphine, 2-8x more potent then morphine
hydomorphine
derived from thebaine, moderate level
oxycodone (pecodan)
strong painkiller, derived from thebaine
oxycontin
derived from thebaine, 1000x potent as morphine, high danger of overdose, used to subdue animals
etorphine
discovered in 1874, derived from German word meaning "herotic"
heroin
derived from morphine, 90% of opioid abuse in the US, illegal, no longer medicinal, 2-3x more potent as morphine and faster, high danger of dependency
heroin
users who __ feel intense immediate reactions; euphoria (rush similar to a sexual orgasm) followed by anesthetizing sensations, then sleep and lethargy
inject
"black tar"
40-80% pure
china white
90% pure
immediate intense euphoria or sense of well being following a hit of heroin
heroin rush
__ depends on how heroin is produced and cut
color
crude heroin is __
dark
purified heroin is __
white
narcotics produced in a lab
synthetic narcotics
created in 2002, mild to moderate narcotic
buprenophrine
derived from morphine, 90% of opioid abuse in the US, illegal, no longer medicinal, 2-3x more potent as morphine and faster, high danger of dependency
heroin
users who __ feel intense immediate reactions; euphoria (rush similar to a sexual orgasm) followed by anesthetizing sensations, then sleep and lethargy
inject
"black tar"'s purity
40-80% pure
china white
90% pure
immediate intense euphoria or sense of well being following a hit of heroin
heroin rush
__ depends on how heroin is produced and cut
color
crude heroin is __
dark
purified heroin is __
white
narcotics produced in a lab
synthetic narcotics
created in 2002, mild to moderate narcotic
buprenophrine
substituted for heroin (detox) in 1943, 3-4 million users, up to 24 hours in duration, same potency as morphine
methadone (dolophine)
used for some heroin addiction treatment, 48-72 hours in duration
levo-alpha-acetyl-methadol (LAAM)
made in 1957, low ptency
propoxyphene (darvon)
made in 1968, 200x more potent than morphine, used in surgery, designer heroins have been formulated (200-3000x more potency of morphine), immediate and short duration, over dosers die with needles in their arms
fentanyl
talwin
pentazocaine
gradual withdrawal from narcotics use
detoxification
clonidine, naltexone, naloxone, methadone
drugs used to ween people of of strong narcotics
naloxone and naltrexone
narcotic antagonists, negates the effects of heroin
constipation, drowsiness, mental clouding, respiratory depression, nausea, vomiting, itching, inability to urinate, constipation, decrease blood pressure, constricted pupils, abuse potential (heroin), drop in temperature, dilate blood vessels
side effects of heroin use
ways heroin enters the body
oral, intramuscular, smoked, sniffed, snorted, subcutaneous (skin popping), intravenous (mainlining)
over __% of heroin users are also HIV positive
50
how heroin is __ and the __ that is taken have a bearing on its effectiveness
administered, dosage
effect of heroin last about __ hours and wears off completely within about 24 hours
4-6
__ people are injecting heroin but __ are smoking it.
fewer, more
the drug used most frequently to treat heroin
methadone
from __ then number of prescription for painkiling drugs has grown dramatically (especially oxycontin)
1996
a natural opioid made in the body
endogenous opioids
naturally occurring neruochemicals, euphoria, painkiller (100x more potent than morphine) (runners high)
enkephalins and endorphins
help moderate your perception of pain
endogenous opioids
__ develops rapidly leading to incredibly large doses, abuse, psychological and physical addiction, severe withdrawal symptoms
tolerance
exaggerated pain, agitation, anxiety, stomach cramps, vomiting, muscle aches, runy nose, flu-like symptoms begins about 12 hours after last use, loss appetite, chills, fever, lasts for 5+ days)
severe withdrawal (dope sickness)
HIV, collapsed veins, blood poison, abscesses, hepatitis, injecting an air bubble
problems because of methods of administration
made in 1960, OTC cough syrup
detromethorphan
made in 1978, antihypertensive
clonidine
nerotransmitter that causes sedation, relaxation, drowsiness, and depression (decreases the normal level of function)
GABA (gamma-aminobutyric acid)
the brain and spinal cord
central nervous system (CNS)
depressants __ the normal activity that goes on in the brain
slow down
the three groups of CNS depressants
barbituates, benzodiazepines, and sleep medications
sleep inducing, anxiety, nervousness, anestheitc, convulsions, mental disorders, epilepsy, schitzophrenia, back aches, multiple sclerosis, muscle strain, parkinsons
medical uses for depressants
depressants found on the illicit market are usually __ manufactured pharmaceuticals that have been diverted for illegal uses
legitamantly
produce relaxation and sometimes sleep, depending on the dose, inhibits CNS, decreases neural activity, slows down mental and body functions, calms, relaxes muscles, soothes, relieves feelings of tension, anxiety and irritability
depressants
a __ of depressants gives relaxation, calm, tranquility
low dose
relieve anxiety, fear and apprehension
sedative
a __ of depressants induces sleep
high dose
induces drowsiness, encourages sleep
hypnotic
depressants at the __ can cause anesthesia and are used during surgery
highest dose
depressants are __ dependent
dose
developed in germany in 1864, marketed in 1903 and are categorized by how long tehy act and how fast they work
barbituaites
at one point, over __ different barbituates existed. today its about a dozen
50
a derivative of barbituric acid that acts as a sedative or hypnotic
barbituites
-act by depressing the respiratory rate, BP, temperature, CNS
-have a high addictive potential
barbituites
-prescribed primarliy for sleep; treatment of convulsions, diabetes, anxiety, anesthetic
-effects are modified by differences in users, previous experience, dosage, set and setting, and how administered
-effects coordination, attention span, reaction time and can be fatal because they alter heart rate, blood pressure, and respiration
-no longer used by most clinicians because of their severe side effects and high potential for abuse
-still used as a general anesthetic
barbitaits
-chemically different from barbituates but produce the same effects
-increase sedation and sleep while reducing anxiety
-many are no longer used by most clinitians
nonbarbituates
chloral hydrate: knockout drops, induces sleep
paraldehyde: used with severely disturbed metal patients, produces horrible smell and bad breath
methaqualone" relieves tension and anxiety without barbiturate like aftereffects; but is extremely addictive and has severe withdrawal effects; removed from the market in 1985
meprobamate: nonbarbiturate that is a minor tranquilzer used to treate psychosomatic conditions; low margin of safety; physical dependence; rarely prescribed today
nonbarbiturates
currently 14 on the market: valium, ambien, xanax, halcion, librium
tranquilizers
most common and safeset prescribed drug to relieve anxiety, induce sleep, relaxation of muscles and lower back pain, reduce panic attacks and epilepsy and controls seizures
tranquilizers
penzodiazepines are often used as __ medications but certain ones are promoted as hypnotics or as anticonvulsant drugs
antianxiety
drugs used to treat allergies (dihenhydramine, hydroxyzine, promethazine)
antihistamines
nausea, lethargy, vomiting, upset stomach, blurred vision, hangover, fever, skin rash, impaired judgment, slurred speech, loss of motor coordination, vertigo, diarrhea, violent behavior, repiratory failure, disruptive personality changes, loss of memory
depressant side effects
profuse sweating, insomnia, muscular twitching, paranoia, vomiting, aches and pains, cramps, quick temper, nightmares, hallucinations, seizures
withdrawal symptoms
__ of patients who are severly dependent on CNS depressants can be very unpleasant and even dangerous
detoxification
LONG TERM USE OF ANY DEPRESSANT WILL LEAD TO ___
DEPNDANCE, TOLERANCE, AND WITHDRAWAL
a plant that contains naturally occurring CNS depressants included in herbal teas
kava kava
ordinairy __ are misused as inhalants
household products
methods of administration for inhalents
-squeezed into a bag, on a hankerchifs, socks or rags, placed over teh nose and inhavled
-spraying aerosols directly into the mouth or nose
-rapidly absorbed through the lungs and into teh bloodstream and quickly distributed to teh brain and other organs
-used in dental practices
-used in minor surgery
-nitrates: diatlate blood vessels and relax muscles
-treat for congestive heart failure
-antidote for cyanide poisoning
medical uses for inhalents
inhalants have __ like properities
anesthetic (sedative-hypnotic depressant)
inhalants are often the __ drugs kids abuse because they are legally obtained, inexpensive, and easy to conceal
first
inhalants are dangerous because a person can die on the first use from serious __
cardiac arrhythmia (sudden sniffing death syndrome)
___: joseph priestly (british chemist) synthesized nitrous oxide (used as an anesthetic)
1776
__: inhalants were highly abused in teh US because you could get a drunkenness without consuming alcohol
1800's
__: inhalants were first used as an anesthetic in dental practice, spread to use in other surgeries
1840
__: OTC nitrates were abused to enhance sexual stamina and pleasure
1960
__: saw an increase of teh use of inhalants in the US
1960's
__: products sold as aromas or incense containing butyl nitrite
1968
__: nitrates were banned in OTC forms
1991
inhalants are the __ leading type of substance abuse among high schools in the US
4th
psychoactive ingredient found in aerosols and solvents
toluene
an early inhalant, dating back to teh 1700's, a volatile, highly flammable liquid
ether
laughing gas, a sweet colorless inorganic gas used as an anesthetic
nitros oxide
brain damage resulting from inadequate supply of oxygen to the brain
hypoxia
inhalant used to treat angia pectoris and congestive heart failure
amyl nitrate
type of nitrate used to treat angina causes vasodilation, flusing, and warmth
isobutyl nitrate
found in perfume and antifreeze
butyl nitrate
readily evaporated at low temperatures
volatile
ability to cause feelings of pleasure and well being
euphorigenic
an irregular heartbeat
arrhythmia
sniffing rags soaked in solvent fluid and held over nose
huffing
inhaling vapors from a bag
bagging
inhaling vapors directly from their origial containers
sniffing or snorting
volatile substances that produce chemical vapors that are inhaled or sniffed
inhalant
dilate blood vessels and relax muscles
nitrates
inhalants are classified by __
how they are used
four classifications of inhalants:
-volatile hydrocarbon solvents
-aerosols
-anesthetics (gases)
-nitrates
-liquids that vaporize at room temp
-adhesives, glues, household solvents
volatile hydrocarbon solvents
-sprays that contain propellants and solvents
-spray paints, hair sprays, fabric sprays
Anesthetics (gases)
-vasodilators, amyl, butyl, and isobutyl
-used to enhance sex
nitrates
short term effects of inhalants. these last about ___
-drooling, hazy, nausea, sneezing, euphoria, gidiness, reduced inhibitions, coughing hypersensitivity, loss of coordination, intoxication, red and watery eyes, haedaches, slurred speech and sniffles
30-40 min
two severe reactions and long term effects of inhalants are__, __ and __
liver and kidney damage, possible brain damage, and cardiac arrest
drugs used at all night raves, parties, dance clubs and bars or trance scenes to enhance sensory experience
club drugs
fairly cheap with an intoxicating high
club drugs
called "drug assisted assault" drugs, colorless, odorless, tasteless drugs that leaves victim powerless, helpless, defenseless, vulerable and unable to recall details, affects short term memory
date rape drugs
most date rape drugs are __
benzodiazepines
teh effects of date rap drugs are greatly enhanced when mixed with __
alcohol
increased use of date rape drugs have led to the passage of the __. this increased federal penalties for use of any controlled substance to aid in sexual assult
drug induced rape prevention and punishment act of 1996
gamma y-hydroxybutyrate; (liquid ecstasy, soap, easy lay, vita-G, Georgia home boy) neurotransmitter that produces relaxation and sleepiness, coma and seizures, also found naturally in the body (GABA)
GHB
-euphoric, sedative, availible OTC until 1992, purchased by body builders to aid in fat reduction and muscle building, body builders to stimulate release of growth hormone
-general anesthesia, treatment for insomnia and narcolepsy, treatment for alcohol and narcotic dependence
GHB
(benzodiazepine) roofies, roach, and rope, powerful depressant (5-10x more than valium
-incapacitaion, amnesia, can be lethal if dose is high enough, not allowed for sale in US, brought in from other countires
rohypnol
dissociative anesthetic; feel sepearated from reality, an out of body experience, an anesthetic that has been approved fro both human and animal used in medical settings since 1970 about 90% legally sold is for veterinary use
ketamine
causes dreamlike states and hallucinations, in high doses can cuase delirium, amnesia, impoaired motor funcitons, high BP, depression and potentially fatal respiratory problems
-frequently used as a general anesthtic for ventrinary procedures
ketamine
a synthetic psychoactive drug chemically similar to the stimulant methamphetamine and the hallucinogen mescaline
MDMA (ecstacy)
__: ecstacy was found on teh streets
1912
characterized by a sharp increase in body temp resulting in liver, kidney, and cardiovascular system failure; leads to changes in brain function affecting cognitive tasks andmemory, leads to bouts of depressoin
-affects neurottransmitter serotonin (possibly depleats is supply semi permenantly)
MDMA ecstacy
the dissociative drugs act by altering teh distribution of teh neurotransmitter __ throughout the brain
glutamate
__ is involved in perception of pain, responses to the environment, and memory
glutamate
drugs such as PCP and ketamine which were originally developed as general __ distort perceptions of sight and sound and produce feelings of detachment, dissociation from the environment and self.
anesthetics
a widely availibly cough suppressant, when taken in high doses can produce effects similar to those of PCP and ketamine
dextrometorphan
stimulants are drugs that cause __.
the heart to beat faster, and BP and metabolism to increase
-treat asthma, narcolepsy, fatigue, short-term weight loss, ADHD, nasal congestion, depression sometimes used to maintain cancer pain
some medical uses for stimulants
stimulants work on the neruotranmitter
__
dopamine
long term use of stimulnants may __ the amount of dopamine or number of dopamine receptors in the brain.
reduce
when a person stops taking a stimulant they crave the drug because without it he or she can't feel much pleasure. they __
dont feel normal
minors chewed __ a mild stimulant to keep them going during the work day
coca
__ Niemann purified cocaine added to lozenges, teas, wine, and eventually coca-cola (kola nuts and cocaine) and tobacco
1859
cocain re-emerged in teh 1960's-70's to replace __
amphetamine
a combination of tobacco and cociane
cocarettes
a stable compound of cocaine, this is a fine powerder that can be snorted through the nasal passage. it cannot be smoked
cocaine hydrochloride
having contaminating substances mixed in to dilute the drug (sugar, talc, arsenic, liocaine, strychnine, etc.)
adulterated
__ caused more premature births, miscarriages, low birth weight, abnomalities, hyperactivity, and possible brain damage to children of women taking the drug
cocaine
-addiction
-irritability and mood disturbances
-resltessness
-paranoia
-auditroy hallucinations
long term effects of cocaine
-increased energy
-decreased appetite
-mental alertness
-increased heart rate and blood pressure
-constricted blood vessels
-increased temp
-dilated pupils
short term effects of cocaine
-cardiovascular disturbances in heart rhythm and heart attacks
-respiratory pain and failure
-strokes
-seizures and headaches
-abdominal pain and nausea
medical consequences of taking cocaine
__ cocaine appears as a white crystaline powder
pure
crack cocaine is the __ form of cocaine and appears as white gravel, slivers, or rocks
most addictive
year that crack cocaine was sythesized
1985
crack cocaine is __ , as opposed to cocaine hydrochloride
smokable
intesnsified form of cocaine now considered one of the most addictive, called poor mans cocaine
-usually smoked in a pipe or mixed with marijuana
-feeling is short, intense, electifying, euphoria
crack
crack is __ then cocaine
cheaper
made by mixing cocaine with baking soda and water and then heating the mixture
crack
-synthetic, developed as a decongestant
-marketed in 1932 as an inhaler (benzedrine) to treat asthma and congestion
amphetamines
amphetamines where synthesized in what year
1887
potent stimulant used to treat narcolepsy, obesity, ADHD
amphetamine
-abuse high in the military, truck drivers, students studying for exams, diet pills high profile individuals
-lasts several hours
causes an arousal alertness, elevates mood, incresese HR and BP
-cause one to be hypersensitive which turns to anxiety, extreme mood swings
-hallucinations, involuntary shaking, severe apprehension, and panic
amphetamines
abuse of amphetamines peaked in the __
late 60's
the from an amphetamine has been compared to an intense __
"whole body" orgasm
a more potent amphetamine
-cheaper, high lasts longer
-powerfully addictive CNS stimulant
even single doses can cause permanent damage to nerve terminals
methamphetamine
both crack and meth lead to __
binging
pysical activity skyrockets, loose appetite, loose desire to sleep, paranoi, aggressive behavior, violnce, nausea, vomiting, diarrhea, muscle twitches, uncontrolled movments, jow clenching, acne, elevates R, BP, HR, BT, convusions
short term effects of meth
sores, tooth decay, anxiety, paranoia, insomnia, psychotic behavior, violence, homicidal or suicidal thoughts, elevated BP, strokes, heart infections, kidney and liver damage, brain damage similar to alzheimers, increaed risk of HIV and hepatitis, death
long term effects of meth
-caffeine (coffee, cola)
-theophyline (tea)
-theobomine (chocolate)
xanthine family (minor stimulants)
caffeine's effects peak __
30-40 minutes
bitter tasting, odorless compound -extracted from the fruit of the coffee arabica plant
-found in coffee, cocoa, chocolate, colas, medications, etc
caffeine
pysical activity skyrockets, loose appetite, loose desire to sleep, paranoi, aggressive behavior, violnce, nausea, vomiting, diarrhea, muscle twitches, uncontrolled movments, jow clenching, acne, elevates R, BP, HR, BT, convusions
short term effects of meth
-increases cellular activity, increases in temp, BP, and general body chemistry, respiration, alertness and mood, opens air passage ways
caffeine
sores, tooth decay, anxiety, paranoia, insomnia, psychotic behavior, violence, homicidal or suicidal thoughts, elevated BP, strokes, heart infections, kidney and liver damage, brain damage similar to alzheimers, increaed risk of HIV and hepatitis, death
long term effects of meth
development of __ aka the consumption of 500-700 mg of caffeine daily led to mood swings, anxiety, insomnia, headaches, laxative/diarrhea, shaking, ned to urinate and cuase hydration, excessive urnation, sweating, feelings of tiredness, irregular HR, changes in BP, stomach pain, and ulcers
caffenism
-caffeine (coffee, cola)
-theophyline (tea)
-theobomine (chocolate)
xanthine family (minor stimulants)
caffeine's effects peak __
30-40 minutes
caffeine can be __
fatal
bitter tasting, odorless compound -extracted from the fruit of the coffee arabica plant
-found in coffee, cocoa, chocolate, colas, medications, etc
caffeine
the impure form of caffeine is __
unsafe
you should keep caffeine consumption to __ mg daily
300
-increases cellular activity, increases in temp, BP, and general body chemistry, respiration, alertness and mood, opens air passage ways
caffeine
development of __ aka the consumption of 500-700 mg of caffeine daily led to mood swings, anxiety, insomnia, headaches, laxative/diarrhea, shaking, ned to urinate and cuase hydration, excessive urnation, sweating, feelings of tiredness, irregular HR, changes in BP, stomach pain, and ulcers
caffenism
caffeine can be __
fatal
the impure form of caffeine is __
unsafe
you should keep caffeine consumption to __ mg daily
300
the solvent used to take the caffeine out of the coffee bean is a potential __
carcinogen
the number one drug of choice for many americans
caffeine
coffee is the __ consumed beverage in the world
most
multiple administratoins of a stimulant every 1-2 hours over a period of days
fan
short intense generalized sensation of total well-being experienced within minutes after intravenous injection racing HR and elevated BP
rush or flash
disturbing period of mental depression when person stops taking a CNS stimulant, ends with prolonged sleep (48 hours)
crash
conversion of cocaine into an alkaline form for smoking, reduces impurities
free basing
__ is a smokable form of methamphetamine
ice
a freebase form of methamphetamine that is smoked in pipe at a temp of around 100 degrees
ice
injectable methamphetamine
speed
injecting combination of cocaine and heroin
speedballing
someone who uses meth over a period of time; goes on binges, shooting up every few hours over the course of several days
speed freak
drugs that suppress appetite for food
anoreximants
regular use of stimulants leads to __, __, and __
tolerance, addiction, and withdrawal
-effects CNS/cardiovascular systems
-depression
-sleep abnormalities
-cravings
-agitaion
-mood swings
distortions
delusions (called a crash)
-can last from hours to 8-10 days but depressions that follows can last for weeks, months, or years
cocaine withdrawal and addiction
-excessive prolonged use leads to weight loss
-sores and nonhealing ulcers
-liver disease and kidney damage
-hypertensive disorders, cerebral hemorrhage and heart attack
-seizures, aggression, and unpredictable behavior
-delusions of extraordinary abilities
-violence, reslessness, and agitaion
-hallucinations and paranoia
side effects of using stimulants
the dose, purity, the method of administration mid set of user and the social and psychological setting
what the side effects of stimulants are dependant on
methods of administration for stimulants
-ingestion (swallow, drink tea)
-inhalation (snorting, most common method; peak effects in 10-15 min)
-intravenous (peaks effects in 30 sec)
-smoked (peak effects in seconds)
-absorbion (chewing or rubbing in mouth or around gential area)
the most common method of stimulant administration
inhalation (snorting)
synthetic powerful stimulant the produces a burst of energy and a prolonged euphoria
metcathinone (KAT) 1991
natural extract of shrub, approved as decongestant but used as diet pill, used by athletes to make weight
ephedrine
mild CNS stimulant used for depression, narcolepsy, ADHD (hyperactivity, impulsivity, inattention) in children, schedule II drug
methylphenidate (Ritalin) 1937
ADHD is the __ identified childhood psychotic behavior
number 1
hallucinogens affect the neurotranmitter receptor of __ which is an inhibitory leading to rapid emotional swings and altered perceptions delusions and visual hallucinations
seratonin
substance that produces psychological effects that are normally asociated only with dreams, schizophrenia, or religous exaltation
hallucinogen
produces changes in perception, thought, and feeling, ranging from distortions of what is sensed (illusions) to sensing objects where none exist (hallucinations)
-highten sensory signals but this is often accompanied by loss of control over what is experienced
hallucinogens
hallucinogens have __ medical uses
no accepted
LSD is listed as a Schedule _ drug
I
used in veterinary medicine as an analgesia and tranquilizer
LSD
a drug which reduces (or blocks) signals to the conscious mind from other parts of the brain, typically but not necessarily limited to the physical senses
dissociative
agent which produces a local or general loss of sensation including pain
anesthetics
there is little evidence of physical dependance for these:
hallucinogens
-heavily used in the 60's and declined in the 70's
-"trip" depends on dose, mind set emotional make-up, and expectations
hallucinogens
-heightened senses
-loss of sensory control
-self-reflection or introspection
-loss of identity or sense of cosmic merging
four major effects of hallucinogens
__: LSD introduced to US to treat mental illness, used by artists and musicians to enhance creativity, and by government as a mild control agent and truth serum
1949
__ (harvard professor) and league of spirtual discovery attempted to legalize LSD in 1960's
timothy leary
__: FDA appealed LSD as a new drug for investigation for mental illness, especially schizophernia to help them develop personal insight and to recall forgotten or repressed experiences also to treat migrane headaches
1953
__: nonmedical interest to deal with problems of society, social upheaval, vietnam war, the establishment, turn on and tune in
1960's
as popularity of LSD grew, so did the __ effects
negative
__: LSD, peyote/mescaline, muschroom/psilocybin and similar drugs became illegal
1963
used as a sacramental plant by members of the native american church as part of their religious ceremony
peyote
class of drug that induce distortion in time, space, alters sensory processing in the brain, causing changes in thought processing
hallucinogen
term used to describe hallucinogenic drugs, stimulating and inebriating
phantasticants
mind manifesting, mind altering properties of naturally occurring hallucinogenic plant substances, heighten perception and consciousness
psychedelic
refer to drugs that produce psychotic-like symptoms
psychotomimetic
drugs that generate psychosis
sychoteogenic
mingling of senses exaggerated seeing sounds and hearing colors, walk on water and fly through the air
synesthesia
repetitions of teh drugs effect without use of drug, often times called a free trip, days, weeks or months later
flashbacks
ergot poisoning muscle tremors, burning, mania, delirium, hallucinaitons, gangrene, convulsions, death
ergotism
body image is distorted, user becomes one with something or someone else, repressed memories
depresonalization
intense nightmarish loss of emotional control with delusions, panic attacks and catatonic seizures
freakout
intense fear, panic, paranoid, delusions, confusion, depression, bodily disomfort
psychotic experience
lucid or clear thought, ability to view problems from a unique perspective
cognitive experience
fascinating changes in sensations and perceptions, intensificaiton of senses
esthetic experience
emergence of unconscious or forgotten material into ones consciousness, reliving
psychodynamic experience
feeling of unity, joy, peace, reverence, wonder, insight
transcendental/mystical experience
there is __ that supports that psychedelic drugs increases creativity
no research
3 types of psychedelic agents
1. LSD types: produce pharmacological effects of tradition psychedelics
2. Phenylethlamines: amphetamine like effects
3. anticholinergics: block receptors for the neurotransmitter acetylcholine
lysergic acid
LSD
derived from ergot fungus,
diethylanide
created LSD in 1938 while trying to synthesize a drug to study psychosis
albert hofmann
-euphoria with crying or laughing: 1-2 hours
-visual hallucinations (2-3 horus)
-distortion of time, disintegration, mood swings, panic: 3-4 hours
stages of LSD
-sold in form of pellets, gelatin chips, and squares of absorbant paper
-ordorless, colorless, tastless
-usually taken orally
-no fatal overdose has been documented but people die b/c of their behavior while on the drug
LSD
derived from cactus (the fleshy green tips are dried for use, low potency short and less intense
Peyote/mescaline
-derived from "magic mushrooms considered sacred, ingested, short and less intense hallucinogen
-more potent than mescaline and less toxic, unpleasant taste
mushroom/psilcybin
-new hallucinogenic drug
-derived from sage family
-used spirtiually in mexico
-produces psychoactive effect when smoked
-when ingested are less intense but but last longer
-no illegal yet but may be soon
salvia divinorum/salvinorin A
-derived from various plant oils including sassafras, is very similar to both mescaline and amphetamines
-ingested, sniffed, or injected
MDA....Phenylethylamine?..
-bitter alkaloid substances
-removed from OTCs in early 1980's
-belladonna, mandrake, henbane
anticholinergic