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9 Cards in this Set

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Liver Function test

Liver Specificity

ALT More Specific

ALT levels

In acute viral hepatitis there is a significant increase in ALT lower levels in Chronic Hepatitis.

Cardiac function test

AST is useful

Location of ALT & AST

Useful indicator of hepatocellular damage. AST is present in mitochondria and cytosol.


ALT found in cytosol

AST/ALT ratio

Albumin and liver

Not a good indicator in early stage liver disease. Half life 20 days. Good indicator of chronic liver disease.

Alpha fetoprotein

Elevated in primary hepatocellular carcinoma. Also in non neoplastic liver disease synthesized by fetal liver cells


Produce by yolk


.6-6.65 normal range in adults


Elevation chronic hepatitis so it limits its diagnostic test for hepatocellular carcinoma.

Immunoglobulins

Serum IgA alcoholic liver disease (cirrhosis)


IgG auto immune hepatitis (chronic)


IgM primary biliary cirrhosis


These changes are non specific