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9 Cards in this Set

  • Front
  • Back

Cholesterol follows which other metabolic pathway just with two additional steps?

Cholesterol synthesis begins with the same first three steps as Ketone Bodies Synthesis.



Cholesterol deviates from this pathway after the formation of HMG-CoA.

Step 1

Step 2

Step 3

Step 4

What is the Enzyme for Step 1?


Additional Reactant?


And Byproduct?

E: Thiolase


AR: None


BP: Releases CoA-SH

What is the enzyme for Step 2?


Additional reactant?


And Byproduct?

E: HMG CoA Synthase


AR: Acetyl-CoA


BP: CoA-SH

What is the Enzyme for Step 3?Additional Reactant?


And Byproduct?

E: HMG-CoA Reductase


AR: (2) NADPH


BP: (2) NAD+ and CoA

What is the Enzyme for Step 4?Additional Reactant?


And Byproduct?

E: Mevalonate-5-Phosphotransferase


AR: ATP


BP: ADP