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62 Cards in this Set

  • Front
  • Back

Step 1

Glucose

Step 2

G6P

Step 3

F6P

Step 4

FBP

Step 5

GAP + DHAP

Step 6

1,3 - BPG

Step 7

3PG

Step 8

2PG

Step 9

PEP

Step 10

Pyruvate

Step 1

Step 2

Step 3

Step 4

Step 5

Step 6

Step 7

Step 8

Step 9

Step 10

Glucose

G6P

F6P

FBP

GAP + DHAP

1,3 - BPG

3PG

2PG

PEP

Pyruvate

Number of Steps in in Glycolysis?

10

Number of Rxn. in Glycolysis?

10

Between which stages have two reactions?

Between 5 and 6.

Enzyme of Rxn. 1

Hexokinase


Mg+2



(Phosphorylation)

Enzyme of Rxn. 2

Phosphoglucose Isomerase (PGI)



(Isomerization)

Enzyme of Rxn. 3

Phosphofructokinase (PFK)


Mg+2



(Phosphorylation)

Enzyme of Rxn. 4

Aldolase



(Carbon-Carbon bond cleavage)

Enzymes of Rxn. 5 and 6

Triose Phosphate Isomerase (TIM)



Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)



(Oxidation-Reduxtion)

Enzyme of Rxn. 7

Phosphoglycerate Kinase (PGK)


Mg+2



(Phosphorylation)

Enzyme of Rxn. 8

Phosphoglycerate Mutate (PGM)



(Isomerization)

Enzyme of Rxn. 9

Enolase


Mg+2



(Dehydration)

Enzyme of Rxn. 10

Pyruvate Kinase


Mg+2


K+



(Phosphorylation)

Type of Rxn. of Rxn. 1

Phosphorylation

Type of Rxn. of Rxn. 2

Isomerization

Type of Rxn. of Rxn. 3

Phosphorylation

Type of Rxn. of Rxn. 4

Carbon-Carbon bond Cleavage

Type of Rxn. of Rxn. 5

Isomerization

Type of Rxn. of Rxn. 6

Oxidation-Reduction

Type of Rxn. of Rxn. 7

Phosphorylation

Type of Rxn. of Rxn. 8

Isomerization

Type of Rxn. of Rxn. 9

Dehydration

Type of Rxn. of Rxn. 10

Phosphorylation

Glycolysis vs Gluconeogenesis

Glycolysis breaks Glucose down whereas Gluconeogenesis forms glucose.

Similarities and Differences if Glycolysis and Gluconeogenesis

The only difference is reaction steps are Glycolysis steps 1,3, and 10. Which in turn are steps 1, 8, and 10.

Glycolysis Step 1 vs Gluconeogenesis Step 10

Step 1 of glycolysis involves Hexokinase transforming Glucose into G6P.



Step 10 in Gluconeogenesis involves Glucose-6-phosphatase (G6Pase) transforming G6P into Glucose.

Glycolysis Step 3 vs Gluconeogenesis Step 8

Step 3 of Glycolysis involves PFK transforming F6P into FBP.



Step 8 of Gluconeogenesis involves FBPase transforming FBP into F6P.

Energy source for Steps 10 and 8 of Gluconeogenesis...

Whereas Steps 1 and 3 of Glycolysis use ATP to phosphorylate their substrates, Steps 10 and 8 of Gluconeogenesis use Water (H20) to dephosphorylate their substrates.

Glycolysis step 10 vs Gluconeogenesis Step 1

Step 10 on Glycolysis uses Pyruvate Kinase to transform PEP to Pyruvate where as Step 1 in Gluconeogenesis is comprised of two enzymes, Pyruvate Carboxylase, and PEPCK.

The 2 enzymes of Step 1 Gluconeogenesis

Pyruvate Carboxylase and PEPCK

Step 1 Gluconeogenesis: Pyruvate Carboxylase

Converts Pyruvate to Oxaloacetate.



Energy source is ATP.


By products are ADP and Pi.

Step 1 Gluconeogenesis: PEPCK

Converts Oxaloacetate to PEP.



Energy source is GTP.


By products are CO2 and GDP.

Importance if Oxaloacetate

Any by product of Glycolysis, intermediates if the Krebs Cycle, and carbon skeletons of amino acids can be converted back to glucose, but first THEY MUST be converted to Oxaloacetate first.