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36 Cards in this Set

  • Front
  • Back
Needs as hetertrophs
i. Reduced organic compounds (can’t make their own)
ii. Essential nutrients – those that must be supplied in the diet
Heterotrophs essential nutrients
1. Are not the same for all animals
2. Amino acids – 9 – 10 cannot be synthesized by humans
3. Fatty acids – it is hard, but not impossible, to become deficient in the two essential (to mammals) fatty acids, linoleate and linolenate
4. Vitamins – nutrients needed for metabolism; usually act as coenzymes
5. Minerals
Modes of acquisition
Absorbtion: in medium that has nutrients present you can absorb nutrients; example tapeworm.


Filter Feeding: opens mouth and filters it. Filters large volumes usually of a liquid.
Fluid feeders: sucking mouth parts acess fluid meal
Substrate feeder: consumes substrate.

Swallowers. : animals that don’t have the components to bite eat only things that fit in mouth.

Biters: can tear into pieces to eat.

Pre-digesters: prey digested outside body.

Symbioses: bacteria.
Alimentary Canals
deal with processing, digestion and secretion
Alimentary canals (processes)
Oral Cavity - mastication, start of digestion

Stomach - storage, mixing, acidification, more digestion

Small intestine - i. Near – duodenum, secretion of many enzymes, lots of digestion, secretion of bicarbonate to neutralize stomach acid
ii. Far – jejunum and ileum, responsible for more digestion, uptake of nutrients


LArge Intestine - water absorbtion

rectum - feces storage.
Mouth
Mechanical and chemical processing
Chewing reduces size
siliva digests carbohydrates
esophogus
transports food
Stomach
Mechanical and chemical processing
(digestion of proteins)
Small intestine
Chemical processing and absorption
(digestion of proteins, fats, carbohydrates;
absorption of nutrients and water)
large intestine
Water absorption and feces
formation
Rectum
holds feces
anus
eliminates feces
Digestion
Breaks down polymers and macromolecules into monomers
to basic building blocks nothing less then five monomers

ii. All forms of life (that is, all kinds of food) share the same chemical structures, and therefore the same monomers

Each biologic polymer has a hydrolytic enzyme to break it down
Carbohydrate digestion types
polymers are starches, glycogen, and cellulose (and chitin). No animal can digest cellulose (without help)
Carbohydrate digestion process
ii. Salivary amylase starts to digest polysaccharides in mouth, continues in stomach

iii. Pancreatic amylase (more than salivary) continues to digest polysaccharides down to the disaccharide level. Secreted into small intestine

iv. Disaccharidases digest specific disaccharides into simple sugars
Disaccharidases
bound to S.I. endothelium (brush border)

2. Maltase for maltose, Sucrase for sucrose, Lactase for lactose, etc.
Protein Digestion
i. Proteins are polymers built up of 20 different amino acids
ii. Proteases are responsible for digestion. Can be specific or non-specific
Protein Digestion Process step 1
Starts in stomach Pepsin is secreated by chief cells, inactive form is pepsinogen

is a specific protease only cleaves to certain amino acids

Acidity plus pre-existing pepsin converts inactive to active form
Protein digestion process step 2
iv. Acidity in stomach due to secretion of gastric juice (containing hydrochloric acid) by parietal cells lowers pH to 2.
1. Kills bacteria
2. Denatures proteins, allowing easier access for hydrolytic enzymes and breakdown of ECM
3. Stomach wall protected by mucus coat, rapid turnover of cells
Protein digestion process step 3
v. After a few hours in the stomach, “acid chyme” is released by the pyloric sphincter, a small amount at a time, into duodenum.
Protein digestion process step 4
vi. Proteases secreted into small intestine (S.I.)
Enzymes in small intestin
1. Trypsin (from trypsinogen) specific protease, secreted by pancreas
2. Chymotrypsin (from chymotrypsinogen) specific protease, secreted by pancreas
3. Carboxypeptidase (from procarboxypeptidase), non-specific (attacks C-terminal), secreted by pancreas.
4. Aminopeptidase, non-specific (attacks N-terminal), secreted by S.I. epithelium.
5. Enteropeptidase – secreted by S.I. epithelium; activates trypsin, which activates others.
6. Dipeptidases – bound to epithelium, split dipeptides into single amino acids
Fat Digestion
i. Fats are not polymers – three fatty acids attached to glycerol via ester bonds.
ii. Digested by lipase (from pancreas), secreted into S.I.
iii. Fat needs to be emulsified for hydrolysis to occur
1. Bile salts are detergents that break up fat globules
2. Bile salts are produced in the liver and stored in the gallbladder
Nucleic acid digestion
in lumen of small intestine i. Nucleases (from pancreas) break down DNA, RNA

ii. Nucleotidases: nucleotide to nucleoside and phosphate
iii. Nucleosidases: nucleoside to bases and sugars
Anatomy of Intestinal lining
ii. Each villus contains capillaries, lacteal (lymph vessel), covered with carbohydrate-rich glycocalyx filaments
iii. Coated with bound digestive enzymes that produce monomers near point of uptake
Absorbtion of nutrients in S.I.
i. Simple diffusion -- fatty acids, monoglycerides through membrane, some sugars and alcohols through pores
ii. Carrier-mediated transport – hydrophilic, large molecules like amino acids and larger sugars
iii. Active transport – amino acids, glucose
Lipid uptake
i. After diffusion, fats are recreated in the epithelium from monoglycerides and fatty acids. These are packaged with cholesterol and coated with protein to form chylomicrons.
ii. Chylomicrons are transported by exocytosis from epithelium to lacteal, and enter the bloodstream from the lymphatic system
uptake of nutrients in the blood
i. Other than fats, nutrients mainly enter the blood in the capillaries of the villus
ii. These capillaries rejoin to form the hepatic portal vein, which empties into the liver.
iii. The liver modifies the composition of the blood, storing excess sugars and amino acids
Reabsorption of water
a. Large intestine reabsorbs water and inorganic ions from the lumen
b. Adds mucus to help form feces
c. Symbiotic bacteria in the L.I. form necessary vitamins (especially K), in many animals help in digestion through fermentation
Hormonal control
A complex mixture of possitive and negative feedback controls include:

b. Gastrin

Secretin

d. Cholecystokinin
Gastrin
is secreted by the stomach into the blood stream, in response to the presence of food, induces further secretion of HCl
secretin
is secreted by the duodenum, targets pancreas (release bicarb) and stomach (lower motility) in response to food
cholecystokinin
secreted by the duodenum in response to fatty acids or amino acids, targets pancreas and gallbladder
Gastric inhibitory peptide
in response to high levels of fatty acids, inhibits gastric activity
Cellullous digestion
can be digested by Rumimants.
which include cattle, shep, deer, giraffs
Rummamint stomach structure
i. Rumen – site of fermentation; rumination
ii. Rumen + reticulum = first division
iii.Omasum + abomasum = second division.
Abomasum is true stomach with digestive enzymes.