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30 Cards in this Set

  • Front
  • Back

Sir Charles Scarburgh

Doctor that treated King Charles II in 1685 to rid him of convulsions. Eventually went into a coma and died.


-Shaved his head


-Placed mustard plasters withirritants containing the Spanish fly


-Fed a substance from a crushed skull of an‘innocent man’


-Given extracts of all theherbs and animals of the kingdom


-Lastly, given a stone from the stomach of agoat.



Misao Okawa

Oldest women alive in the world:


- 116


- from Japan

Marie-Louise Meilleur

Oldest women in Canada ever:


-117


- from Kamouraska, Quebec

Jeanne Calment

Oldest women of all time:


- 122


- Died in 1997


- Smoked until she was 100


- Ate chocolateevery day.





Dr. Harpps Father

Survived the Flu Epidemic of 1911.


- Recorded the death of 5 people in a diary.


- 14yrs old at the time.


- Kemps Balsam was the 'cure'.

Sir William Osler

"Father of Medicine"


- Founded McGill Faculty of Medicine in 1874.


- Helped found Johns Hopkins Faculty of Medicine.



Sumerians

2 200 B.C had 16 beer recipes.

Friedrich Serturner

First person to extract morphine pure.

Hippocrates

Focused on excluding superstition.




ex.


- solution for baldness - rub the fat of a snake on your head


- solution for 'night blindness' - eating of liver.


- solution for child birth pain - bark of willow.

Dioscorides

Documented plants that hold true today for medical purposes:


- Wormwood - absinthe


- Saffron - diuretic

Paracelcus

"A poison can be a potion, depending on the concentration"


- All drugs are poisons and only the right dosage makes it stop being a poison.


Blood - Air


Phlegm - Water


Black Bile - Earth


Yellow Bile - Fire



Jakob Bohme

Shoemaker in Germany


" Signature of all things"


- God marked everything with a sign, that gives an indication for their purpose.


ex.


- Walnuts look like a brain - good for brain.


- Willow trees grow in marshy areas - extract is for wound inflammation and pain.



William Withering

Discovered the solution to dropsy (congestive heart failure)


- Foxglove

Pelletier and Caventou

First purified Quinine, derived from Cinchona plant to cure Malaria.

Joseph Lister

- Discovered Phenol as an antibacterial agent and sprayed it on women to survive birth better.


- 1950s used for dandruff control, bad breath and deoderant.


Led to thymol in mouthwash - Listerine.



Thomas Roddick

Discovered antisepsis.


- McGill's Roddick Gates.

Paul Ehrlich

Discovered Salversan.


- Remedy for syphilis.


- Nobel Prize winner in 1908.

Dr. Frances Kelsey

- Didn't allow Thalidomide into the USA.


- It then caused birth defects.


- Received her Ph.D from McGill.


- Died at 101 last month.


- Discovered connection between sulphonamide and diethylene glycol using rats.

Durham Humphrey

Added in 1951 to the 1938 FDA Act, 2 sets of categories- OTC and Prescription Drugs.


- Before, the only prescription drugs were narcotics and cocaine.

Julian Adams

Helped put Velcade on the market to treat multiple myeloma. (Bone marrow cancer)


- Dr. Harpp's student at McGill.



Henry Leroux

1829 first extracted Salicin from willow bark.


- impure substance

Rafaelle Piria

Purified Salicin to make Salicylic Adic.


-Side effects: Bitter, and severe stomach pain.

Felix Hoffman

Chemist at Bayer that decided to add the acetyl group to make Acetyl Salicylic Acid (ASA).


- Easier on the stomach.


- To treat his father's arthritis pain.





Duisberg

Directer of Hoffman's lab - first person to promote use of Aspirin.

Sir Walter Raleigh

Evaluated darts used in the "Three Tree Poison"


- Discovered curare a substance from vines of a tree. (chondodendron tomentosum)

Sir Charles Waterton

Discovered that curare can be used to cause muscle relaxation without causing death.


- Led to Claude Bernard's discovery.

Claude Bernard

Discovered that curare blocks nerve impulses that connected the central nervous system to the muscles.


- Curare can cause paralysation.


- Active ingredient = Tubocurarine

Harold Griffith

First to apply curare into surgery in 1942.


- At the Queen Elizabeth Hospital on an appendectomy.


- Major breakthrough in physiology because surgeons can now perform surgeries without muscles moving.


- "Preand Post-Griffith eras"



Dr. Harold Watkins

Turned sulfanimide (pill form) into an elixir for the southern USA.


- Drug dissolved in diethylene glycol not water or alcohol.


- Interactions were fatal and led to over 100 deaths.


Point: Similarly structured molecules can have dramatic differences.


***Caused 1938 FDA act for drug testing.

Harvey W. Wiley

Organized "Poison Squad"


- 12 individuals fed "gourmet meals" although gelatine capsules with substances were added into random foods.


- Caused acute symptoms (nausea, vomiting...)


Result: Many foods were taken off the market.


- Pure Food and Drug Act of 1906.