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4 Cards in this Set

  • Front
  • Back

Vancomycin

Purple coccoid temples = activity against gram positive bacteria


No mercy pharaoh = activity against MRSA


Golden staph = Staph aureus


Temple wall Hieroglyphs = inhibition of cell wall synthesis by directly binding to D-ala-D-ala oligopeptides


Altered wall builder = altered penicillin binding proteins (PBPs) resistant to beta-lactams


Ineffective altered wall builder = altered PBPs ineffective against vancomycin


Ineffective Guard = beta-lactamases ineffective against vancomycin

Vancomycin Treatments

Meningitis Helmet = CNS penetration = activity against penicillin resitant Strep pneumo


Fish bones = bone penetration - treat MRSA osteomyelitits


Nurse = activity against nosocomial MRSA infection


Biofilm on line and valves worker = activity against staph epidermidis


Heart Shaped headpiece = empiric treatment of endocarditis


Diplococcus rock drums = activity against Enterococcus


Temple flowing chocolate = treats clostridium deficile

Vancomycin resistance

D-LAC hieroglyphs with dead explorer = altere peptidoglycan structure (D-ALA-D-LAC) confers resistance to vancomycin

Vancomycin Side effects

Red egyptian statue holding beehive = Red man syndrome due to released histamine


Blue vines = thromboplebitis


Gong and broken ear = oto toxicity (rare but common when also have aminoglycosides)


Falling Kidney = Nephrotoxicity


Slingshot native in dress = Eosinophilia and systemic symptoms (DRESS) syndrome