Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
10 Cards in this Set
- Front
- Back
|
von Willebrand factor |
Peeling Won wille brand field = Damaged vascular epithelium exposes von Willebrand factor and collagen Holding 1b bat = factor GP1b receptors activate platelets Home plate = activated platelet degranulation Aggregated players = due to ADP(poster), 5-HT(happy face helmet), TXA2 (Batters box A2) |
|
|
Thromboxane pathway |
Coach Cox = cyclooxygenase 1 synthesizes prostanoids (prostaglandin, TXA2) within platelets Sleeping assistant coach = COX-2 expressed only in inflammation AA minor league game = Arachidonic acid precursor |
|
|
Aspirin |
ASA umpire = antaganizes coach
Acetyl-Whistle = Covalently (irreversible) acetylates COX-1 and COX-2 Swollen and red umpire = "Pseudo allergy" due to excess leukotriene synthesis Umpire Chewing = Chew aspirin in acute MI Corked bat = Aspirin + ADP receptor inhibitors prevent coronary stent thrombosis Black paint stroke - good in strokes |
|
|
Thienopyridines End with -grel |
Hot dog grill above ADP poster = ADP receptor inhibitors Greasy grill pipe = reduce cardiovascular events in patients with peripheral artery disease Grill on Angina anvil = Reduce cardiovascular events in patients with coronary artery disease Broken heart strings banjo = Good in MI Black paint stroke - good in strokes |
|
|
Ticlopidine |
TY COBB shirt ADP receptor antagonist Falling granules = Can cause granulocytopenia A CBC is needed if you use this drug |
|
|
Fibrinogen |
Fries Crowd from seats 2b-3a aggregating = surface receptor2a/3b binds fibrinogen to promote platelet aggregation |
|
|
Abciximab |
ABC sportscaster grabbing fries = blocks GP2b/3a receptor preventing platelet aggregation Antibody shaped microphones = is a monoclonal IgG antibody Broken Plates = thrombocytopenia |
|
|
Eptifibatide Tirofiban |
Tied game is a fib block GP 2b/3a receptor to prevent platelet aggregation Broken Plates = thrombocytopenia |
|
|
Phosphodiesterase inhibitors |
Don't phoster disinterest stand (dipyridamole= two pyramid stand) (cilostazol = So lost the ball, wide sleeves = vsodilation) sign up for cAMP = increase cAMP in platelets, impairing platelet function |
|
|
cilostazol |
So lost the ball wide sleeves =causes vasodilation) Dirt hitting leg = treats symptoms of claudication due to peripheral artery disease Stolen heart base = can cause coronary steal Red crown hat = coronary artery vasodilation |
