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16 Cards in this Set
- Front
- Back
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What is Schilling classification?
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It was established when Victor Schilling, a german hematologist, noticed that in many diseases there is an increase in the percentage of immature neutrophils.
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What exactly was the first chart that he developed?
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It reported the percentages of the the different neutrophilic cell types and in part was arranged as follows:
Under normal conditions, myelocytes= 0 metamyelocytes= 0 Band cells= 2-6 Segmented cells= 55-75. |
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What can one notice about this chart?
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The immature cells are on the left side of the chart. If percentages of immature cells increased, Schilling referred to it as a "shift to the left".
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What is a degenerative shift to the left?
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When a shift to the left is accompanied by a low white cell count.
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A degenerative shift to the left is seen in typhoid fever. TRUE/FALSE
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TRUE. It is caused by a depression of the cell factories in the bone marrow.
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What is a regenerative shift to the left?
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When the shift to the left is accompanied by a high white cell count.
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A regenerative shift is seen in pneumonia. TRUE/FALSE
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TRUE. There is a stimulus of the marrow cell factories.
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What is the significance of a shift to the right?
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It implies an increase in hypersegmented neutrophils.
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When is a shift to the right seen?
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It can be seen in pernicious anemia, caused by the malabsorption of vit. B12.
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Normal values for differential counts vary with the age of the patient. TRUE/FALSE
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TRUE. Childrens blood normally contains 0-2% basophils, 0-5% eosinophils, 25% to 75% neutrophils, 30-70% lymphocytes, and 0-8% monocytes.
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Leukocytosis with an increase in the percentage of neutrophils indicates a severe infection with a good response of the bone marrow. TRUE/FALSE
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TRUE.
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What should a normal Schilling classification chart look like?
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Neutrophilic myelocytes-0
'' '' metamyelocytes-0 neutrophilic band cells-2-6 '' '' segmented cells-55-75 lymphocytes-20-35 monocytes-2-6 eosinophilic segmented cells-1-3 basophilic segmented cells-0-1 |
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What is the significance of the appearance of numerous juvenile cells?
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Metamyelocytes, indicates irritation of the bone marrow with regeneration.
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A falling white cell count with the number and maturity of neutrophils progressing means what?
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Indicates recovery.
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In tbc, an increase in monocytes indicates activity in the infected area. TRUE/FALSE
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TRUE. An increase in lymphocytes indicates healing.
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Eosinophils increase in allergic and parasitic infections. TRUE/FALSE
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TRUE.
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