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12 Cards in this Set
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Child with erythematous macular rash, fever; started on face, then to trunk and extremities; hx of URI:
What family of virus? Transmission? Control? |
measles
Paramyxviridae respiratory droplets MMR active vaccine - live attenuated; passive immunization post exposure |
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Child with cheek swelling after fever, malaise, anorexia; discomfort with chewing/speaking:
Two surface glycoproteins? Where does it replicate? Complications? |
Mumps virus - enveloped RNA virus
humagglutinin neuraminidase (HN), Fusion protein (F) respiratory epithelial cells parotitis (most common), orchitis, meningitis/encephalitis, pancreatitis |
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What is the best test to confirm mumps?
Which Ab appears early in infection and indicates current infection? Which Ab indicates past infection, and Ab's last for years? |
Ab's against envelope Ag (V Ag, HN)
S Ab V Ab - (HN) |
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Migrant worker with fever, rash, achy joints, 2 months pregnant, 2 adults and 3 kids have similar illness - virus and family?
Greatest concern with this virus? How to check for rubella? |
Rubella - German measles - Togaviridae (+ssRNA)
effect on fetus (CRS) - can cause abortion, fetal cataracts, heart defects, deafness serum IGM, virus isolation from culture |
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Rash, no fever/illness, mother thinks it's Parvovirus; virus structure and family:
Complications? "Fifth disease", "slapped cheek" appearance: What makes up the rash? Complications? |
Parvoviridae - ssDNA virus
fetal hydrops - 10% death of fetus; aplastic crisis Erythema Infectiosum Ag-Ab complexes in skin; aplastic crisis |
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7 y/o with maculopapular rash on soles of feet, palms of hands, vesicular lesions under tongue:
What virus family? Where do enteroviruses replicate? How are they shed? Who is usually infected? |
Hand, Foot, Mouth: (Coxsackie A, Enterovirus)
Picornaviridae replicate in GI (TQTQ) respiratory, feces children |
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Symptoms from enterovirus infections are from what?
Coxsackie can cause what other illnesses? |
virus being deposited in tissues - NOT Ag-Ab complexes (different from other skin virus infections)
herpangina, summer rash |
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dsDNA, enveloped, causes oral and genital lesions:
Where does HSV stay latent in the body? Common presentation of HSV-1 infection? Problems in the immunosuppressed? |
HSV-1 - oral, HSV-2 - genitals
ganglion child - gingivostomatitis, fever, malaise, lesions; adult - severe pharyngitis for a week pneumonia, severe mucocutaneous lesions |
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Virus for chicken pox, shingles:
Pathogenesis of shingles? Why is VZV so contagious? Control? |
Varicella Zoster
latency in ganglia + impaired T-cell function = recurrence along dermatomes transmitted by respiratory AND skin lesions Vaccine - recommended for children 1 y/o, seronegative adults; passive immunization for imunocompromised |
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Common infection, associated with roseola, transmitted via saliva:
Associated with Kaposi's sarcoma: causes warts - dsDNA viruses, non-enveloped: HHV types associated with malignant lesions, included in vaccine: |
HHV-6, HHV-7
HHV-8 HPV HPV-6, 11, 16, 18 |
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First disease to be eradicated, and virus family:
How is its replication unique? Acidophilic inclusions in cytplasm: Prevention? |
Smallpox - Poxviridae
Does not involve cell nucleus - makes its own enzymes (big virus) Guarnieri bodies vaccination eradicated in 1977; Cox pox (Vaccinia) current vaccine |
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Molluscum contagiosum - where are the lesions and what do they look like?
How is this virus different from herpesvirus? |
dome shaped, translucent lesions
child - trunk, face adults - genitals AIDS - all over virus stays in skin lesions - when lesions gone, virus gone |
