******infectious agent(s) (include type of agent, virulence factors and life cycle): HSV-1 infections are highly contagious.
******when was the disease first described:
mode(s) of transmission: HSV-1 is generally transmitted through oral-to-oral contact when coming into contact with the virus in saliva, surfaces in or around the mouth, or other sores. It can also be transmitted to the genital area trough oral-to-genital contact, …show more content…
People who are immunocompromised are more susceptible to recurring HSV-1 outbreaks with more severe and obscure complications, such are keratitis or encephalitis. HSV-1 often times does not result in noticeable symptoms, but people will experience "cold sores" that can tingle, itch, or burn. These unpleasant sensations often precede the appearance of such sores. These sores can reappear throughout a person's lifetime with the frequency of outbreaks varying among individuals. Genital HSV-1 infections can also be asymptomatic or have mild symptoms, characterized by one or more genital or anal blisters or ulcers. Varying in severity, the frequency of the recurrence of symptoms from genital HSV-1 is spread out. HSV-2 causes infections inside of or on the surface of the genital or anal area. Like HSV-1, the often asymptomatic occurrence of HSV-2 result in a lack of diagnosis and can remain unnoticed. 10-20% of people with HSV-2 report a prior diagnosis of genital …show more content…
Most HSV-1 infections are acquired during childhood before the age of sexual activity, as with the case for Africa, but can be acquired in adulthood. As of 2012, 3.7 billion people under the age of 50, which compile 67% of the population, were estimated to be infected with HSV-1. The prevalence of the infection was the highest in Africa at 87% and the lowest in North and South America, ranging from 40-50%. As of 2012, 140 million people worldwide aged 15-49 were estimated to have genital HSV-1 infections, but the occurrence of such infections varied substantially from region to region. Most genital HSV-1 infections are thought to occur in North America, South America, Europe, and the Western