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17 Cards in this Set

  • Front
  • Back
Each of the following statements regarding TTN of the newborn is true EXCEPT?

A) infants born by c-section are at increased risk of developing TTN

B) Residual pulmonary functional disability is common among infants who have TTN

C) There is a higher incidence of TTN than respiratory distress syndrome among term infants

D) TTN often improves markedly in 12-24 hours
B) Residual pulmonary functional disability is common among infants who have TTN
The primary pathophysiologic problem in RDS is...

A) Alveolar hyaline membranes
B) Prematurity
C) Strutural immaturity of the lung
D) Surfactant deficiency
D) Surfactant deficiency
Fetal surfactant maturation is enhanced by each of the following except:

A) administration of corticosteroids to the mother during pregnancy
B)elevated fetal insulin levels
C)premature rupture of the membranes
D)use of tocolytic agents to delay onset of labor
C)premature rupture of the membranes

you want to prolong them
The incidence of bronchopulomary dysplasia can be reduced by each of the following measures except:

A)administration of fluid volumes at 10% above normal requirements
B)closure of PDA
C)restriction of O2 administration
D)treatment of pulmonary infection
A)administration of fluid volumes at 10% above normal requirements

want to restrict fluids
A newborn is delivered at an estimated gestational age of 36 weeks by emergent C-section for fetal distress. The maternal history is significant for prolonged rupture of membranes. The infant has evidence of respiratory distress, and the chest radiograph shows patchy infiltrates and pleural effusion, as indicated by obliteration of both costophrenic angles. Of the following, the most likely cause of these chest radiographic findings in this infant is:

A)Hyaline Membrane disease
B)Meconium aspiration syndrome
C)Neonatal pneumonia
D)Pulmonary edema
E)Pumonary hemorrhage
C)Neonatal pneumonia

not 100% on this one..but thats what I think (note: there were no answers given)
prolonged rupture of membranes does what?
helps mature surfactant
A rare cause of respiratory distress among term newborns is a congenital abnormality of surfactant proteins. The most common of these conditions is deficiency of surfactant protein B (SP-B). Of the following, the most accurate statement regarding SP-B is that:

A) SP-B deficiency is accompanied by reductions in SP-A and SP-C in airways
B) SP-B deficiency is transmitted as an autosomal dominant trait
C)The gene for SP-B is located on chromosome 22
D) the most common defect in SP-B deficiency is a frame shift mutation
E)The typical pathological finding in SP-B deficiency is generalized alveolar atelectasis
D

a) levels are fine
b) recessive
c) on chrom 2
d) CORRECT-Frame shift!
Several developmental abnormalities of lung structure can cause respiratory distress in the newborn. Of the following, the most common structural lesion that can cause respiratory distress in the newborn is:

A) congenital cystic adenomatoid malformation
B) congenital lobar emphysema
C)primary pulmonary lymphangiectasia
D)pulmonary hypoplasia
E)Pulmonary sequestration
B) congenital lobar emphysema
A radiograph that reveals increased interstitial markings with fluid in the interloabar fissures in an infant who has respiratory distress is most likely to represent:

A) hyaline membrane disease
B) lobar pneumonia
C) meconium aspiration syndrome
D) transient tachypena of the newborn
E) transposition of the great vessels
D) transient tachypena of the newborn
The most likely diagnosis associated with the radiographic findings of a diffuse ground glass appearance to the parenchyma is an infant who has respiratory distress is:

A) hyaline membrane disease
B) lobar pneumonia
C) meconium aspiration syndrome
D) transient tachypena of the newborn
E) transposition of the great vessels
A- RSD

A) hyaline membrane disease: correct
B) lobar pneumonia: bilateral consolidations (white out)
C) meconium aspiration syndrome: patchy atelectasis with inflammation
D) transient tachypena of the newborn: interstitial fluid
E) transposition of the great vessels: increased pulmonary vascularity
The radiographic finding of patch atelectasis with areas of hyperinflation in an infant who has RDS is most indicitive of?

A) hyaline membrane disease
B) lobar pneumonia
C) meconium aspiration syndrome
D) transient tachypena of the newborn
E) transposition of the great vessels
C) meconium aspiration syndrome
For an infant who has RDS, increased pulmonary vascularity on a radiograph most likely represents?

A) hyaline membrane disease
B) lobar pneumonia
C) meconium aspiration syndrome
D) transient tachypena of the newborn
E) transposition of the great vessels
E) transposition of the great vessels
Among the following, the information that is most helpful in distinguishing cyanotic heart disease from pulmonary parenchymal disease in a newborn who has respiratory distress is:

A) Decreased PO2 in blood gas
B) Gestational age less than 32 weeks
C) Maternal infection during the third trimester
D) Respiratory rate of 70 breaths/min
E) Results of hyperoxygenation test
E) Results of hyperoxygenation test
Which of the following is the primary test used for newborn screening of CF?

A) DNA testing for CFTR genetic mutation?
B) Immunoreactive trypsinogen in blood
C) Meconium trypsin concentration
D) Nasal potential difference
E) Sweat Chloride Concentration
B) Immunoreactive trypsinogen in blood
A 2 year old girl is being evaluated for cough, loose stools, and failure to thrive. Which of the following tests has the highest sensitivity and specificity in establishing the diagnosis of CF in this child?

A) DNA testing for CFTR genetic mutation?
B) Immunoreactive trypsinogen in blood
C) Meconium trypsin concentration
D) Nasal potential difference
E) Sweat Chloride Concentration
E) Sweat Chloride Concentration
a 12 year old boy who has CF is admitted for worsening cough and difficulty in breathing of 1 month's duration. Sputum cultures are obtained and intravenous antibiotic therapy begun. Presence of which of the following pathogens in his sputum poses the greatest danger to other pts who have CF with whom he has direct contact

A) burkholderia cepacia
B) Kelb pneumo
C) PCN resistant Strep pneumo
D) Pseudomonas
E) Staph A
A) burkholderia cepacia
A 4 year old girl is being evaluated for cough, loose stools, and poor weight gain of 6 months duration. Her parents have noticed that she craves salty foods. Two separate sweat electrolyte tests performed show Cl values of 70 mEq/L and 64 mEq/L. Which of the following statements is most correct:

A) A diagnosis of CF should be confirmed by NPD
B) the management regimen for CF should begin
C) The presence of a single CFTR mutation is required to confirm the diagnosis of CF
D) The serum immunoreactive trypsinogen assay should be performed
E) The test should be repeated while the girl is eating a low-salt diet
B) the management regimen for CF should begin