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9 Cards in this Set
- Front
- Back
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what happens to neoplasms
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they proliferate to form new tissues.
apoptosis is not initiated. cell # is not constant signs to regullate/stop cell growth are ignored |
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when do cells divide
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when told to do so by growth factors.
they attach to receptor proteins typically on membranes of nearby cells which work by affecting G proteins to turn on intracellular messengers. those make second messengers and act inside the cell to stimlate division |
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pro-oncogenes
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normal genes that code for normal proteins used in cell division
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oncogenes
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mutated pro-oncogenes that promote autonomous cell growth
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what do tumor suppressor proteins do
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inhibit proliferation of cells in a tumor, p53 specific
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naming tumors:
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benign-
tissue name + oma malignant- epithelial tissue: tissue name + carcinoma mesenchymal tissue: tissue name + sarcoma |
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benign tumors contain cells that are..
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like normal tissue cells
they may perform the normal function of the tissue and have a capsule around them (so do not invade other tissues) |
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malignant tissues contain cells that..
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do not look like normal adult cells
the cells divide rapidly and tumors metastasize + travel in the blood or lymph nodes |
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cancer cell characteristics
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mutations in proliferative phase
if early= more undifferentiated= malignant if late= more differentiated= benign |
