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92 Cards in this Set

  • Front
  • Back

What is metabolism?

Metabolism is the sum total of all chemical reactions that take place in living cells

What are metabolic pathways?

A series of chemical reactions controlled by enzymes

What does the metabolic pathway start and finish with?

Starts with a substrate and finishes with an end product

What is an Anabolic pathway?

Requires energy and is used to build up large molecules from smaller ones (biosynthesis)

What is a catabolic pathway?

Releases energy to break down large molecules into smaller ones (degradation)

Can metabolic pathways be reversed?

Metabolic pathways can be reversible or irreversible.


Almost all pathways are reversible

What proteins are found in bedded within the membrane?

Protein Pumps


Receptor protein


Enzyme protein


Channel protein


Structural protein


Glycoproteins


By the presence or absence of a particular enzyme

By the presence or absence of a particular enzyme

What is the induced fit model?

When enzymes bind to their substrate The active site of the enzyme is slightly changed to better fit the substrate after the substrate binds

Active site affinity;

The active site has a high affinity to the substrate


The active site has a low affinity to the product

What does an enzyme do to reaction?


Biological catalyst

An enzyme binding to its substrate lowers activation energy for the reaction

The enzyme is saturated

The enzyme is saturated

What affect does increasing substrate concentration have?

Substrate concentration increases the enzyme reaction rate until all active sites are occupied by the substrate

What happens at saturation?What are the three types of inhibition

Increasing concentration of substrate will have no affect


Graph levels off

What are the three types of inhibition?

Competitive inhibition


Non-competitive inhibition


Feedback inhibition

What are inhibitors are used to do?

Inhibitors can be used for stopping enzyme from binding to its substrate


As a result inhibitors can directly control the progress of the metabolic pathway

What is competitive inhibition?

Inhibitor molecule binds to the active site of an enzyme


Increasing substrate concentration can reverse competitive inhibition

Why can A competitive inhibitor compete with the substrate?

Because they have a similar molecular shape

Why does substrate What is non-competitive competitiveconcentration reverse competitive inhibition?

The substrate eventually dilutes the inhibitor so that all enzyme molecules bind to the substrate

What is non-competitive inhibition?

Inhibitor does not bind to active site but binds to a different part of enzyme and changes the active site shape

What is feedback inhibition?

An end product in a metabolic pathway binds to an enzyme at the start of the pathway

Why does feedback inhibition occur?

Because there is a high end products concentration

What is ATP?

Adenosine triphosphate


Energy carrying molecule used in cells because it can release energy very quickly

What processes make up respiration?

Glycolysis


Citric acid cycle


Electron transport chain

Where does glycolysis occur?

The cytoplasm

Where does the citric acid cycle take place?

In the matrix of the mitochondria

Where does the electron transport chain occur?

In the inner membrane of the mitochondria

What is phosphorylation?

When ATP is re-generated from ADP plus PI

How is respiration controlled?

Respiration is the metabolic pathways of enzyme controlled reactions in which glucose is oxidised to produce ATP

What are the two types of respiration?

Aerobic respiration


Fermentation

Does glycolysis require oxygen?Why is

No it is anaerobic

Why is the regeneration of ATP described as a net gain?

Two ATP are invested


Four are generated


Resulting in a net gain of two


What enzyme removes the hydrogen ions and electrons?

Dehydrogenase enzymes remove the hydrogen ions and electrons from this cycle

What coenzyme are the hydrogen ions and electrons passed onto?

NAD


This passes them to the inner mitochondria membrane for the electron transport chain

What are the two types of fermentation?

Alcoholic fermentation


Lactate fermentation

Is oxygen needed for the citric acid cycle?

Yes it will only take place if oxygen is present as it is an aerobic process

What does acetyl CoA combine with to make citrate?

Oxaloacetate

What is the byproduct of the citric acid cycle?

Carbon dioxide is the byproduct

How many ATP are produced during citric acid cycle?

2

What is the electron transport chain?

It is the collection of proteins found on the inner membrane of the mitochondria

What releases hydrogen ions and electrons into the transport chain?

NADH

Where do the electrons transfer their energy to During the electron transport chain?

They transfer their energy to the proteins in the membrane

What does the energy from the electrons in the electron transport chain do?

Provides energy for the hydrogen ions To be pumped across the inner mitochondrial membrane

What is oxygen’s role In the electron transport chain?

Oxygen is the final hydrogen ion and electron acceptor

How much ATP is produced in total from one molecule of glucose?

38 ATP

What are the products of fermentation in plants?

Ethanol and carbon dioxide

What are the products of fermentation in animals?

Lactic acid

What is a metabolic rate?

Amount of energy expended by an organism in a given period of time

What is BMR

Basal metabolic rate


(Metabolic rate)

How can metabolic rate to be measured?

Oxygen consumption


Carbon dioxide production


Heat production

What apparatus can we use to measure metabolic rate?

Resoirometers


Oxygen probes


Carbon dioxide probes


Calorimeters

Heart


Blood vessels


Blood

Heart


Blood vessels


Blood

What does the respiratory system consist off?

Lungs Or gills


Structures involving breathing processes

Arteries;

Carry blood away from the heart


High-pressure

Capillaries;

Smallest blood vessels with exchange nutrients gases and waste products between the blood and the body tissue

Veins;

Carry blood back to the heart


Low pressure

What are the two chambers of the heart?

Atria and ventricles

Atria;

Where blood enters the heart

Ventricles;

Where blood leaves the heart

What circulatory system do mammals and birds have?

Complete double circulatory system

Complete double circulatory system;

Hello higher metabolic rates


No mixing of oxygenated and deoxygenated blood

What type of circulatory system do amphibians have?

Incomplete double circulatory system

Incomplete double circulatory system;

Three heart chambers


Two atria one ventricle


Mixing of oxygenated and deoxygenated blood

What type of circulatory system does fish have?

Single circulatory system

Single circulatory system;

Two heart Chambers


One ventricle one atrium

Maintaining an organisms metabolic rate is affected by what abiotic factors?

Temperature


PH


Salinity

What are conformers?

Dependent upon the changes in external environment

Can control internal environment regardless of external environment change

Can control internal environment regardless of external environment change

Conformers advantages And disadvantages?

Low metabolic costs


Can only exploit a narrow range of ecological niches


Less adaptable to environmental change

Regulator advantages and disadvantages?

Can exploit a wider range of ecological niche is


High metabolic costs in order to achieve homoeostasis

Internal conditions that can be controlled


Temperature, salt concentration, blood glucose levels, and water concentration

Internal conditions that can be controlled


Temperature, salt concentration, blood glucose levels, and water concentration

What is homoeostasis?

The maintenance of the bodies internal environment within tolerable limits


Despite the change in external environment

Negative feedback control

Negative feedback control

What is Thermo regulation?

And example of negative feedback control


Mammal maintains their body temperature at constant 37°

What is the hypothalamus?

The bodies temperature monitoring centre in the brain?


Sensitive to nerve impulses that come from receptors in skin

Examples of effectors for Thermo regulation;

Sweat glands, blood vessels, and muscles around the body

Order of nerve impulses for Thermo regulation;

Stimulus


Receptor


Hypothalamus


Effector


Response

What is Vascodilation?

Where blood vessels allow blood to flow to skin surface where heat is lost


Too hot

What kind of body due to stop overheating?

Vascodilation


Sweat


Decrease in metabolic rate

How can the body increase temperature?

Vasoconstriction


Hair erector muscles contract


Shivering

What is Vasoconstriction?

Blood vessels are restricted and bloodflow to the skin stop so less heat is lost

Because it insures optimal enzyme controlled reaction rates and diffusion rates to maintain metabolism

Because it insures optimal enzyme controlled reaction rates and diffusion rates to maintain metabolism

What is dormancy?

Dormancy is a period when an organism is metabolic activity decreases and allows for the conservation of energy

What happens in periods of dormancy?

Organisms metabolic rate decreases


Heart rate decreases


Breathing rate decreases


Body temperature to decreases

What are the two types of dormancy?

Predictive


Consequential

What are adverse conditions?

Conditions beyond the tolerable limits of an animal’s metabolic rate

What are some examples of dormancy

Hibernation


Aestivation


Daily torpor

Adaptation that allows an animal to escape cold water and food shortages over winter


Heart rate, body temperature, metabolic rate decreases

Adaptation that allows an animal to escape cold water and food shortages over winter


Heart rate, body temperature, metabolic rate decreases

A period of reduced activity


Reduce metabolic rate of animals with high metabolic rate


Short period of time

A period of reduced activity


Reduce metabolic rate of animals with high metabolic rate


Short period of time

What is aestivation?

Adaptation for Survival in high temperatures or drought

Involves expending energy to relocate to an environment that is more suitable


Innate or learned

Involves expending energy to relocate to an environment that is more suitable


Innate or learned

What methods can be used to track migration?

Transmitter


Geo locator


Target with a marker