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38 Cards in this Set

  • Front
  • Back
process by which a drug is transferred from its site of entry into the body to the bloodstream
Adverse drug effect
undesirable effects other than the intended therapeutic effect
Allergic effect
an immune system response that occurs when the body interprets the drug administered as a foreign substance & forms antibodies against the drug
glass flank that contains a single dose of medication for parenteral admin.
Anaphylactic reaction (anaphylaxis)
most serious allergic effect
Antagonist effect
effect either less than that of each drug alone
Cumulative effect
toxicities can occur from this; occurs when the body cannot metabolize 1 dose of a drug before another dose is administered
depends on blood flow to the tissues, the drug’s ability to leave the bloodstream, & drugs ability to enter the cells
Drug tolerance
occurs when the body becomes accustomed to the effects of a particular drug over a period of time
process of removing a drug, or its metabolites (products of metabolism), from the body. Kidneys excrete most drugs. Lungs are primary route for the excretion of gaseous substances, such as inhalation anesthetics. Many drugs are excreted through bile in the gastrointestinal tract. Sweat, salivary, & mammary glands are also routes of drug excretion
Generic name
which identifies the drug’s active ingredient, is the name assigned by the manufacturer that first develops the drug
amount of time it takes the 50% of the blood concentration of a drug to be eliminated from the body
Idiosyncratic effect
any unusual or peculiar response to a drug that may manifest itself by over response, under response, or even the opposite of the expected response
inspiration; acto of breathing in
Intradermal injection
administered into the dermis, just below the epidermis
Intramuscular injection
injection into deep muscle tissue, usually of the buttock, thigh, or upper arm
Intravenous route
most dangerous route of administration because the drug is placed directly into the bloodstream, it cannot be recalled, & its actions cannot be slowed
biotransformation, the change of a drug from its original form to a new form. Liver is primary site for drug metabolism
Mini-infusion pump (syringe pump)
for intermittent infusion is battery operated & allows medication mixed in a syringe to be connected to the primary line & delivered by mechanical pressure applied to the syringe plunger
Official name
name by which the drug is identified in the official publications, United States Pharmacopeia & National Formulary (USP & NF)
outside the intestines or alimentary canal
Peak level
highest plasma concentration; should be measured when absorption is complete
study that deals w/chemicals that affect the body’s functioning
Intravenous piggyback delivery system
requires the intermittent or additive solution to be placed higher than the primary solution container
pharmacologically inactive substance
PRN order
“as needed” order
STAT order
a single order, but it’s carried out immediately
Subcutaneous injections
administered into the adipose tissue layer just below the epidermis & dermis
Synergistic effect
effect greater than that of each drug alone
Teratogenic effect
known to have the potential to cause developmental defects in the embryo of fetus & are definitely contraindicated
Therapeutic range
concentration of drug in the blood serum that produces the desired effect w/out causing toxicity
Topical application
usually intended for direct action at a particular site, although some can have systemic effects & are given for systemic effect
Toxic effect
(toxicities) specific groups of symptoms related to drug therapy that carry risk for permanent damage or death
Trade name
referred to as the brand name or proprietary name, is selected by the drug company that sells the drug & is protected by trademark
Trough level
point when the drug is at its lowest concentration, & this specimen is usually drawn in the 30-min interval before the next dose
glass bottle w/a self-sealing stopper through which the medication is removed
Volume-control administration set
medication is diluted w/a small amount of solution & administered through the patient’s intravenous line
Z-track technique
recommended for all IM injections to ensure medication does not leak back along the needle track & into the subcutaneous tissue