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15 Cards in this Set

  • Front
  • Back

What are haemoglobin's?

Molecule, oxygen binding sites, similar in all organisms (although different affinities depend on different shape)

What molecule is haemoglobin?

Protein with quaternary structure

Describe the role of haemoglobin and red blood cells in the transport of oxygen?

haem (or heme) group which is an inorganic group containing one iron ion.


4 iron ions in each haemoglobin molecule, and iron ions are directly responsible for binding the oxygen molecules



  • Readily associates with oxygen where gas exchange takes place rapidly

Describe the role the loading, transport and unloading of oxygen in relation the oxyhaemglobin dissociation?

  • Oxygen diffuses across the alveoli into the haemoglobin in red cells Haemoglobin has a high affinity for oxygen in the high oxygen concentration that exist there
  • Readily dissociates at the tissues requiring it

Coordination of heartbeat

1. SAN sends wave of electrical activity / impulses (across atria) causing atrial contraction;Accept excitation2. Non-conducting tissue prevents immediate contraction of ventricles / prevents impulses reaching the ventricles;3. AVN delays (impulse) whilst blood leaves atria / ventricles fill;4. (AVN) sends wave of electrical activity / impulses down Bundle of His;4. Allow Purkyne fibres / tissue5. Causing ventricles to contract from base up;

Left ventricle to aorta

1. Atrium has higher pressure than ventricle (due to filling / contraction) causing atrioventricular valves to open;Start anywhere in sequence, but events must be in the correct order.1. Accept bicuspid, reject tricuspid1. Allow: blood passes through the valve = valve open / blood stopped from passing through the valve = valve closed2. Ventricle has higher pressure than atrium (due to filling / contraction) causing atrioventricular valves to close;3. Ventricle has higher pressure than aorta causing semilunar valve to open;Points 1, 2 and 3 must be comparative: eg higher 3. Allow aortic valve4. Higher pressure in aorta than ventricle (as heart relaxes) causing semilunar valve to close;4. Allow aortic valve5. (Muscle / atrial / ventricular) contraction causes increase in pressure;

What is the general pattern of circulation in an organism?

Mammals have closed, double circulatory system


(reduction in pressure in the lungs)


Arteries, capillaries and veins


Pulmonary viens and arteries


Renal vein and artery


Vena cava and Aorta


Diffusion within tissues (due to large surface area)

Describe the gross structure of the human heart?

Blood is supplied by the coronary arteries


Blood flow is controlled by atria-ventiruclar valves (bicuspid, left, tricuspid, right)


Left deoxygenated, right oxygenated


Two chambers, atrium, ventricle

Why do organisms require a circulatory system?

Large, multi-cellular


Low S/A volume ratio


Transport system


Raw materiais


Specialised exchange surfaces


High enough rate maintained

What do the valves do?

Maintain a unidirectional flow of blood

What is the structure of an artery in relation to it's function?

1. thickest wall, enabling it to carry blood at high pressure / withstand
pressure surges;
2. most elastic tissue, which smoothes out flow / maintains pressure;
3. most muscle which maintains pressure;
4. muscle in wall to control blood flow;



What is the structure of a vein in relation to it's function?

Thin wall does not have to withstand high pressure

What is the structure of the capillary in relation to function?

Thin wall, allowing diffusion/exchange;





only endothelium present, allowing short diffusion pathway;



What do all blood vessels have in common?

Have endothelium that reduces friction;

How is tissue fluid formed?

Arterial end


High hydrostatic pressure


Net movement out


Small molecules (ultrafiltration)


Exchange of metabolic substances


Water potential lowers in capillary and higher in tissues


Osmosis


Loss of hydrostatic pressure in the venous end


Lymph vessels


Hydrostatic pressure


Contraction of body muscles (aided by valves in the lymph vessels)