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38 Cards in this Set

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Cell Cycle

The steps that allow a cell to split into two cells.

Allows growth




Allows cells to repair damaged tissue

Mitosis

The division of the nucleus

Chromosomes separate into two identical sets




One of the most important and main process of the cell cycle

Interphase

Period of growth and DNA replication between divisions

Separated into three phases




A cell spends most of its life in this process

G1/G0

Stage where growth occurs and macromolecules are made

Stage of normal cell processes




Same as G2

S

Stage where DNA replication occurs

Synthesis




Stage between G1 and G2

G2

Second stage of growth and marcomolecule making

Same as G1/G0




Stage after S

M

Stage where mitosis and cytokinesis occur

Final stage of the cell cycle




The cell would not separate with this stage

Restriction Point

Where growth signals tell the cell to finish the entire cycle

One thing that may occur during G1




There is no longer a requirement for growth to finish the cycle

Cytokinesis

When the cytoplasm splits into two separate cells

Occurs during stage M




The very last process that occurs in the cell cycle

Daughter Cell

A cell that is created after the cell cycle is complete

Result of the cell cycle is two ______




Each ______ has one strand of DNA from the parent cell

Nucleotide Base Pairing

Each nitrogen base has a specific pair that it must be to function properly

A-T, C-G




The cells know these very well and must keep them the same

Hydrogen Bond

A bond formed between two hydrogen atoms

A and T have a double _____

A and T have a double _____





Antiparallel

When two things are parallel, but run in opposite directions

DNA strands are ________

DNA strands are ________





DNA Polymerase

Helps to build a new, matching strand for each of the original strands of DNA

Works with RNA primer




Added to the DNA synthesis process by RNA polymerase

Semiconservative Replication

Each daughter molecule has one original strand of the DNA

Means that half the strand of DNA is original


Histone

A type of protein that DNA wraps around

Forms a nucleosome

Chromosome

Made up of protein and DNA, containing genetic information


Found inside the nucleus



Chromatin

The complex of proteins and DNA that forms chromosomes

Makes up chromosomes



Mutation

A change in the sequence of a cell's DNA

There are three types of _____




The X-Men are humans with _____

Mutagen

A cause of a mutation


Chemicals, Radiation, Viruses



______ are very often carcinogens

Excision Repair

When an incorrect base pair is attached to DNA it is removed



A base pair is cut out of the DNA and replaced

Leading/Lagging Strand

The names for the strands that nucleotides are added onto

One gets nucleotides continuously




One gets nucleotides in segments

Sister Chromatids

Either of the two copies of a chromosome


Not brothers, but _____

Centromere

The piece that attaches the sister chromatids


Holds the chromosome together

Aneuploid

Cells that form when mutations occur as chromosomes are being separated

Extra or missing chromosomes

Prophase

When chromosomes become visible as pairs of chromatids

The first phase of mitosis




Nuclear envelope disappears

Metaphase

Chromosomes align themselves in the middle of the cell

Third phase of mitosis




Like a type of "tug of war" with the chromatids

Anaphase

Phase where the genetic information of the parent cell is put into the two daughter cells

Fourth phase of mitosis



Phase with the most to do with the nucleus

Telophase

When the chromatids/chromosomes move to opposite ends of the cell

Final phase of mitosis


Two nuclei are formed

Centrioles

Organelle in animal cells that develops spindle fibers


Found in most eukaryotic cells

(Mitotic) Spindle (Fibers)

Form a protein structure that divides genetic information


Connect things

Spindle Poles

Opposite ends of the cell

Similar idea to the North and South Poles



Equal to centrosome in function

Kinetochore

Proteins on chromatids that spindle fibers attach to during cell division


Help to separate sister chromatids


Cyclins

Proteins that regulate the progression of the cell cycle


Bind to and activate kinases


Kinases

Enzymes that transfer a phosphate group from ATP to other cell cycle enzymes to activate them

From the family of phosphotransferases

Cell-Cycle Arrest

When proteins stop the cell cycle until mistakes are fixed



The entire team has to stop if someone in an earlier stage makes a mistake



All processes stop

Cancer

Uncontrolled cell growth due to mutations in checkpoint proteins


A vey sad disease

Checkpoints

Proteins monitor the condition of the DNA, chromosomes, and mitotic spindle to prevent producing mutated cells

Areas where proteins check in on the cell cycle